1-Methylhydantoin-2-Imide: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 22, 2025
Share:
Inside this article:

All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is 1-Methylhydantoin-2-Imide?

1-Methylhydantoin-2-Imide is a lab-created molecule belonging to the hydantoin family, a group of small ring-shaped compounds often used in personal care formulas. Chemically described as 4H-Imidazol-4-one, 2-amino-1,5-dihydro-1-methyl-, it features a compact five-membered ring with both nitrogen and oxygen atoms that readily interact with water. The ingredient was first explored in the late twentieth century when researchers were looking for gentle, water-soluble skin conditioners to replace heavier animal-derived proteins. Today it is synthesized by reacting methylhydantoin with mild oxidizing agents under controlled temperature and pH, yielding a stable white powder that dissolves easily in water-based formulations.

Because it is lightweight and non-oily, 1-Methylhydantoin-2-Imide shows up in a variety of leave-on and rinse-off products. You will most often find it in facial moisturizers, hydrating sheet masks, soothing lotions for sensitive skin, after-sun gels and some anti-aging serums where a smooth, soft finish is desired without adding grease.

1-Methylhydantoin-2-Imide’s Cosmetic Benefits/Uses

This ingredient is prized by formulators for one key role.

As a skin conditioning agent, 1-Methylhydantoin-2-Imide binds to the outer layer of the skin and helps it hold on to water. This boosts immediate softness and suppleness, reduces the look of surface roughness and supports a comfortable, hydrated feel throughout the day. It does all this without leaving a heavy film so it suits lightweight or gel-based products as well as richer creams.

Who Can Use 1-Methylhydantoin-2-Imide

This lightweight conditioning agent plays nicely with almost every skin type. Oily and acne-prone complexions appreciate its water-binding ability without added grease, while dry or mature skin gains an extra layer of moisture retention. Sensitive skin tends to tolerate it too since it is free of fragrance and known irritants. There are currently no reports suggesting it is unsuitable for any specific skin type.

Because 1-Methylhydantoin-2-Imide is made entirely in the lab from non-animal feedstocks it is considered suitable for vegans and vegetarians. No animal-derived enzymes or by-products are used in its synthesis.

Available safety data do not flag special concerns for women who are pregnant or breastfeeding when the ingredient is used topically at the low concentrations found in cosmetics. Still this is not medical advice and anyone expecting or nursing should run any skincare routine past a qualified healthcare provider to be on the safe side.

The molecule is not known to increase photosensitivity so it does not make skin more prone to sunburn. Standard daytime sun protection is still recommended for overall skin health.

Potential Side Effects/Adverse Reactions

Individual responses to topical 1-Methylhydantoin-2-Imide can vary. The effects listed below are only potential outcomes and are unlikely for most users when the ingredient is formulated correctly.

  • Mild redness or warmth at the application site

If any of these effects occur stop use immediately and seek medical advice if discomfort persists

Comedogenic Rating

Rating: 0/5. 1-Methylhydantoin-2-Imide is fully water soluble, has no oily or waxy components and does not leave an occlusive film that could clog pores. For that reason it is considered non-comedogenic and is generally suitable for people who are prone to acne or breakouts. One thing to remember is that the overall formulation matters, so a product packed with heavy oils could still trigger congestion even if this particular ingredient does not.

Summary

1-Methylhydantoin-2-Imide is used mainly as a skin conditioning agent that helps the outer layer of skin latch onto moisture. By forming a light, water-attracting veil it boosts softness and suppleness without adding grease, making it flexible for gels, lotions and creams.

It is a bit of a behind-the-scenes player rather than a household name, popping up in some hydrators and calming formulas but not yet enjoying the buzz of trendier actives.

Available research and industry reports show a very low risk of irritation, allergy or pore clogging, so most people can use it with confidence. Still, every complexion is unique so it is wise to patch test any new product that features this ingredient just to be safe.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search