3-Aminopropane Sulfonic Acid: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 22, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is 3-Aminopropane Sulfonic Acid?

3-Aminopropane sulfonic acid, sometimes written as 3-aminopropane-1-sulphonic acid, is a small water-soluble molecule that combines an amino group with a sulfonic acid group. This dual nature lets it interact well with both water and oily substances, making it handy in personal care formulas. The ingredient is typically synthesized in a lab through a controlled reaction that attaches a sulfonic acid group to a three-carbon chain carrying an amino group. Because the process is straightforward and yields a high-purity powder, manufacturers can produce it consistently at scale.

The cosmetic world started paying attention to 3-aminopropane sulfonic acid in the late 1990s when formulators sought alternatives to harsher surfactants. Its mild yet effective cleansing ability and its knack for improving the way other ingredients dissolve made it a practical choice for gentle products. Today you can spot it in facial cleansers, micellar waters, shampoos, body washes, sheet masks and even some lightweight gel moisturizers where a clear low-irritation formula is desired.

3-Aminopropane Sulfonic Acid’s Cosmetic Benefits/Uses

Below are the key ways this ingredient supports a beauty formula

  • Cleansing: Its amphiphilic structure helps lift dirt, oil and daily buildup from the skin or hair without stripping natural moisture, giving products a gentle yet thorough cleanse
  • Hydrotrope: Acts like a solubility enhancer, allowing otherwise stubborn oily or scented ingredients to dissolve evenly in water-based formulas which keeps products clear, stable and easy to rinse off

Who Can Use 3-Aminopropane Sulfonic Acid

This ingredient is generally well tolerated by all skin types including sensitive, oily, dry and combination because its cleansing action is mild and its pH is close to skin friendly levels. Those with very compromised or broken skin may feel a slight tingle if a formula contains a higher concentration but most leave-on products use low amounts to avoid that issue.

3-Aminopropane sulfonic acid is synthesized entirely from non-animal raw materials so it is suitable for vegans and vegetarians. No animal by-products are involved in its production or purification steps which also appeals to brands seeking cruelty-free status.

Current safety data show no specific concerns for topical use during pregnancy or while breastfeeding. Still this is not medical advice and anyone who is pregnant or nursing should have a doctor review the full ingredient list of any product they plan to use.

The molecule does not make skin more sensitive to sunlight so extra photosensitivity is not expected. Users should of course keep up a regular sunscreen habit for overall skin health.

Potential Side Effects/Adverse Reactions

Reactions to topical 3-Aminopropane sulfonic acid differ from one person to another. The points below outline potential side effects that could occur yet they are uncommon when the ingredient is used at the levels typically found in cosmetics.

  • Transient stinging or tingling, especially on freshly exfoliated or compromised skin
  • Mild redness or irritation if the formula is left on the skin for an extended period
  • Dryness when combined with other strong surfactants in high-foaming cleansers
  • Allergic contact dermatitis in individuals already sensitized to sulfonic acid derivatives
  • Eye irritation if product accidentally gets into the eyes before rinsing

If any of these effects occur stop using the product and seek advice from a qualified healthcare professional

Comedogenic Rating

Rating: 0 / 5

3-Aminopropane sulfonic acid is fully water soluble, has no oily or waxy backbone and rinses off easily so it does not linger inside pores. Because it lacks the large hydrophobic chains that typically cause clogging it is considered non-comedogenic.

Suitable for acne-prone or breakout-prone skin.

Its ability to help dissolve oily ingredients can even improve the clarity of formulas aimed at blemish control, though results still depend on the overall product blend.

Summary

3-Aminopropane sulfonic acid works as a mild cleanser and a hydrotrope. Its amphiphilic structure latches on to both water and oil allowing it to lift grime while also helping fragrance oils actives and other lipophilic ingredients stay dissolved in watery bases.

The ingredient has a quiet presence rather than superstar status, showing up mostly in gentle cleansers micellar waters and clear gels where a low-irritation profile is valued.

Overall safety data are strong with low irritation and no pore-clogging risk, yet it is always smart to perform a quick patch test whenever you add a new product to your routine, especially if your skin is sensitive.

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