Potassium Glycyrrhizinate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What is Potassium Glycyrrhizinate?

Potassium Glycyrrhizinate is an ingredient commonly used in cosmetic products for its skin conditioning properties.

It is derived from licorice root through an extraction process. This process involves isolating glycyrrhizic acid from the root and converting it into its potassium salt form. This conversion enhances the ingredient’s stability and solubility, allowing for seamless integration into various cosmetic formulations.

In cosmetic formulations, this ingredient serves to enhance the skin’s condition by promoting softness, smoothness, and overall health. It achieves this by forming a protective film on the skin’s surface, which helps to lock in moisture and prevent water loss. This film also acts as a barrier against environmental stressors, contributing to the maintenance of skin health and resilience over time.

Its primary benefits stem from its anti-inflammatory and soothing qualities, making it particularly valuable in products designed for sensitive or easily irritated skin types.

Who Can Use Potassium Glycyrrhizinate?

Potassium Glycyrrhizinate is suitable for all skin types, including sensitive and irritated skin. Its soothing and anti-inflammatory properties make it a great choice for anyone looking to calm their skin.

For vegans and vegetarians, this ingredient is generally suitable because it is derived from licorice root, a plant-based source. However, it’s always a good idea to check the overall formulation of the product to ensure there are no other animal-derived ingredients.

Women who are pregnant and/or breastfeeding can typically use products containing Potassium Glycyrrhizinate. However, as with any cosmetic ingredient, it’s always best to consult with a healthcare provider to ensure it is safe for individual circumstances.

Potential Side Effects/Adverse Reactions

Side effects and reactions to the topical application of Potassium Glycyrrhizinate can vary from person to person.

  • Redness
  • Itching
  • Swelling
  • Rash
  • Burning sensation

If you experience any of these side effects while using Potassium Glycyrrhizinate or a product containing it, discontinue use immediately and consult a healthcare professional.

We get it, these side effects can sound extreme or scary, but adverse reactions to Potassium Glycyrrhizinate are actually quite rare.

That’s why patch testing is so important when it comes to using cosmetic products. It helps ensure that your skin won’t have an adverse reaction to new ingredients.

Comedogenic Rating

Comedogenicity refers to the potential of a cosmetic ingredient to cause comedones, which are skin lesions commonly known as blackheads or whiteheads. Ingredients with high comedogenic ratings are more likely to clog pores and lead to acne breakouts, while those with low ratings are less likely to do so.

Potassium Glycyrrhizinate has a comedogenic rating of 0. This means it is considered non-comedogenic and is unlikely to clog pores or cause acne breakouts. The rating is based on its chemical structure and its general use in formulations, which do not typically contribute to pore-clogging.

Given its non-comedogenic nature, Potassium Glycyrrhizinate is suitable for those who are prone to acne or breakouts.

Conclusion

Potassium Glycyrrhizinate primarily functions as a skin conditioning agent, helping to soothe and improve the appearance of the skin. While it may not be as widely known or popular as some other cosmetic ingredients, it is similar to other skin-soothing agents in its category.

Overall, Potassium Glycyrrhizinate is considered safe to use in cosmetic formulations. Its non-comedogenic nature makes it a suitable choice for individuals with sensitive or acne-prone skin.

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