Dermaceutic Laboratoire may not yet have the mass-market fame of some beauty giants, but within professional skincare circles its science-first approach is whispered about with genuine respect. The French lab prides itself on dermatologist-tested formulas that often feel more clinical than cosmetic, a reputation that instantly raised my expectations when its Turn Over Rejuvenating Night Cream landed on my bathroom shelf.
The name “Turn Over” practically winks at you, hinting at its promise of speeding up skin renewal. According to the brand, this fragrance-free overnight treatment leans on a high dose of glycolic acid to whisk away dull surface cells, soften wrinkles and restore radiance for all skin types. Lofty claims indeed, especially for something that looks deceptively plain in its white tube.
I committed to a full two-week trial, applying it nightly to face and neck while obeying the strict no-eye-area rule, to see if the cream could live up to its science-backed pedigree and whether it deserves a spot in your routine or your budget.
Disclosure: This is not a paid or sponsored review. The product was purchased with personal funds and every opinion here reflects my own experience. As always with skincare, individual results can vary.
What Is Turn Over Rejuvenating Night Cream?
Turn Over sits in the overnight treatment category, a group of products designed to work while you sleep when skin naturally shifts into repair mode. Unlike day creams that focus on hydration or protection, overnight treatments often deliver active ingredients in higher concentrations with the aim of encouraging cell renewal and addressing concerns like texture, tone and early signs of aging.
This particular formula relies on glycolic acid, an alpha hydroxy acid known for dissolving the glue that holds dead surface cells in place. By loosening that layer, the cream helps fresh skin come forward more quickly which can translate into smoother texture and a bit more radiance over time. The brand positions it as suitable for all skin types and skips added fragrance to reduce the risk of irritation.
Beyond glycolic acid, the ingredient list includes familiar emollients such as caprylic/capric triglyceride and squalane to counter possible dryness, plus glycerin for lightweight hydration. Dermaceutic recommends applying a thin layer to face and neck each evening while steering clear of the eye area then letting the product work undisturbed until morning.
Did It Work?
In the name of scientific rigor I shelved my usual retinoid night lotion for three days before the test run, a move that made me feel like I deserved a lab coat. Fourteen nights felt like a reasonable window to judge real, not placebo, results so I stuck to a strict routine: pea sized amount after cleansing, neck included, no other actives layered on top.
Night one delivered the classic glycolic sizzle. A subtle prickling lingered for five minutes then settled, leaving my skin touchably soft by morning. Encouraged, I pressed on. By the third application I noticed faint dryness along my cheekbones, nothing dramatic but enough to warrant an extra pump of my usual ceramide moisturizer on top. The cream stayed true to its fragrance free promise which I appreciated at 11 p.m. when scents can feel suffocating.
Midway through the fortnight a few tiny clogged pores on my chin surfaced and cleared within two days, the kind of micro purge that tells me exfoliation is actually happening. Texture on my forehead looked smoother under bathroom lighting and makeup glided with less patchiness, an improvement that friends claimed only I could spot but that still counts in my book.
Where the formula fell short was tone and wrinkle depth. My light post-summer sun spot near the temple remained basically unchanged and the fine line between my brows still waved back in the mirror. I suspect a longer trial or a bump in glycolic percentage might shift that needle yet Dermaceutic’s promise of visibly reduced wrinkles in weeks felt optimistic.
By night fourteen my complexion did look a touch brighter and definitely felt polished. No irritation beyond that initial dryness occurred so sensitive-leaning users may fare well. Still, the results felt incremental rather than transformative and I already own acids that deliver similar payoff at a lower price.
So did it work? Partly. Turn Over kept its word on smoothing and gentle resurfacing but stopped short of the dramatic rejuvenation the tube implies. I will finish the tube when my skin needs a mild reset though I am unlikely to crown it a permanent fixture on my shelf.
Turn Over Rejuvenating Night Cream’s Main Ingredients Explained
The star here is glycolic acid, an alpha hydroxy acid with the smallest molecular weight in its family which lets it slip easily into the upper layers of the epidermis. At the relatively high concentration Dermaceutic favors, it breaks down the bonds between dull surface cells so they shed more quickly, nudging fresh skin to the top and helping fine lines look softer over time. Because glycolic can sting or dehydrate, the formula pairs it with classic cushioning agents like glycerin and squalane. Glycerin pulls water into the skin while squalane, a lightweight lipid now commonly sourced from olives rather than shark liver, seals that moisture without leaving a greasy film.
Caprylic/capric triglyceride and dimethicone sit next on the label acting as emollients that give the cream its silky glide. Both are largely well tolerated though caprylic/capric triglyceride has a moderate comedogenic rating which means acne-prone users could see clogged pores if they already struggle with congestion. Comedogenicity is simply a measure of how likely an ingredient is to block pores and trigger breakouts so patch testing is smart if blackheads are a recurring headache for you.
Cetearyl alcohol and PEG-40 stearate thicken the texture and help water and oil components stay happily married. The polymer duo of hydroxyethyl acrylate and sodium acryloyldimethyl taurate keeps the formula stable over months of use while polysorbates act as surfactants that further homogenize the blend. Disodium EDTA chelates metal ions to stop the cream from oxidizing too fast and octadecyl di-t-butyl-4-hydroxyhydrocinnamate is an antioxidant that protects delicate oils from rancidity.
One red flag for strict vegans sits halfway down the list: cholesterol. This skin-identical lipid is excellent for reinforcing the natural barrier yet it is typically derived from lanolin or other animal sources which rules the product out for anyone avoiding animal derivatives entirely. Vegetarians may feel comfortable given the minute amount though sourcing transparency would still be appreciated.
As for moms-to-be, glycolic acid under 10 percent is generally viewed as the gentler alpha hydroxy option during pregnancy yet opinions differ and doctors often advise pressing pause on most exfoliating acids. If you are expecting or nursing, check with your dermatologist before adding Turn Over to the nightstand.
Finally the cream is fragrance free which lowers irritation risk, contains no added colorants, and stays within the safe pH window for glycolic activity so you get results without unnecessary fluff. All in all, the ingredient list reads like a careful balance between clinical potency and barrier respect though it is not flawless for every ethical stance or skin type.
What I Liked/Didn’t Like
After two weeks here is the straightforward rundown of highs and lows.
What Works Well:
- Noticeably smooths texture and leaves skin feeling refined by morning
- Fragrance free formula and balanced emollients kept irritation minimal for me
- Lightweight cream sinks in fast so layering a richer moisturizer on top is easy
What to Consider:
- Results on discoloration and deeper lines were subtle during the trial period
- Those prone to congestion may want to patch test given the presence of caprylic/capric triglyceride
- Price sits at the higher end of glycolic night creams so value depends on personal priorities
My Final Thoughts
After two weeks of dutiful night-time slathering Turn Over settles into that curious middle ground I call “solid but not soulmate.” The glycolic polish is undeniable, the texture is pleasant and my skin woke up feeling smoother, yet the bigger promises of wrinkle softening and spot fading are still waiting in the wings. If you are new to acids or crave a gentle, fragrance free starter this is a respectable option. If you already flirt with stronger AHAs or retinoids you may find the fireworks a little tame. I would hand it a perfectly decent 7/10 and tell a friend to try it only if their budget is comfortable and their goals lean toward maintenance rather than miracles.
For anyone weighing their overnight options I have road-tested plenty of contenders and a few deserve a shout-out. Nocturnal Revive Cream by Deascal is my current all-rounder crush, delivering hydration, gentle exfoliation and barrier support at a wallet-friendly price that makes repeat purchases painless. Those who like a richer, peptide-laced formula might appreciate Advanced Night Restore by Medik8 which leaves skin feeling plush by dawn without clogging pores. Fans of lightweight gel textures could veer toward the cult Water Sleeping Mask by LANEIGE which consistently rescues my face after dehydrating travel days. Lastly, when I want a cosy lavender-tinged cream that tackles fine lines while encouraging blissful sleep, Confidence in Your Beauty Sleep by IT Cosmetics earns its place on the nightstand.
Before you dive in a quick nagging note from your over-protective reviewer: patch test on the jawline for a couple of nights, especially if you are sensitive or layering other actives. Remember that bright smooth skin is a rental not a one-time purchase, so keep using your chosen night cream consistently and protect your results with daytime SPF. Apologies for sounding like your mother, but future you will thank us both.