My 2-Week Review of Regentiv’s Oxygenating Night Cream

Is Regentiv's new overnight treatment the secret to sunrise-ready skin?
Updated on: June 17, 2025
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Regentiv has built a quiet but loyal following in the professional skincare world, celebrated for formulas that feel clinical yet comforting on a bathroom shelf. If the name has slipped your radar till now consider this night cream your formal introduction and the brand’s gentle flex of expertise.

Oxygenating Night Cream arrives with a title that sounds equal parts space mission and spa menu, promising to flood skin with moisture, defend against daily aggressors and generally make beauty sleep live up to its name. In short Regentiv says it hydrates, softens and shields thanks largely to a dose of pure vitamin E and a cocooning texture meant for lights-out repair.

I put those claims to the test over a full two-week stint, swapping out my usual overnight treatment so I could track changes with unfiltered honesty and see if it deserves a place in your routine or just your wish list.

Disclaimer: this is not a paid or sponsored review. The jar came from my own wallet, the verdicts are mine alone and, as ever with skincare, your mileage may vary.

What Is Oxygenating Night Cream?

Oxygenating Night Cream is Regentiv’s entrant in the overnight treatment category, the group of products designed to stay on skin while you sleep and take advantage of the hours when cell repair naturally peaks. Overnight treatments are typically richer than a daytime moisturiser, creating a film that locks in water and counters the moisture loss that can happen under bedroom air or central heating. They also give active ingredients an uninterrupted window to work because there is no makeup or sunscreen sitting on top.

This formula aims to replenish hydration and reinforce what dermatologists call the barrier function, the lipid layer that keeps irritants out and moisture in. It blends occlusive emollients like petrolatum and shea butter, humectants such as glycerin plus a straightforward dose of vitamin E for antioxidant support. The brand positions it as a nightly step after cleansing: smooth a layer over face and neck then leave it to get on with its job until morning.

Did It Work?

Like any serious scientist with a bathroom cabinet I benched my usual overnight treatment for a full three nights before starting Regentiv so my skin could hit a little baseline reset. Fourteen days felt like a fair window to observe real change without drifting into placebo territory.

Each evening I scooped out a blueberry-sized blob, warmed it between palms then pressed it over face and neck. The texture sits between a classic cold cream and a modern gel cream: thick at first touch yet it slips across skin without the waxy drag I half expected from petrolatum on the ingredient list. It left a slight sheen that never migrated onto my pillowcase which I counted as an early win.

First morning results were textbook: plumpness, no tight patches around the nostrils and that soft-focus look you get after a humidifier sleep. By night four the hydration boost felt consistent but not compounding. My skin stayed comfortable through a blustery school-run but redness on my cheeks, usually a stress barometer, looked unchanged.

Heading into week two I paid close attention to barrier signs like flaky corners or sudden sting from my vitamin C serum. None appeared so the cream certainly cushioned against daily aggressors as promised. The promised glow however never pushed past a polite whisper. Fine lines around my eyes looked identical in the magnifying mirror and any antioxidant protection proved impossible to measure outside a lab.

So did it work? Yes on overnight hydration and basic barrier support, less so on delivering a visible next-level radiance. At seven out of ten it earns a respectful nod but I will finish the jar rather than rush to repurchase. My regular night treatment, pricier but livelier on results, is already waiting in the wings.

Main Ingredients Explained

Top of the bill is tocopherol acetate, better known as vitamin E. Its main job is to act as an antioxidant, scavenging the free radicals produced by UV light or pollution so they do not nibble away at your collagen. Vitamin E is also a mild anti-inflammatory and a decent emollient which helps explain the calmed, cushioned feel I woke up with.

Hydration comes from a trio of workhorses: glycerin pulls water into the upper layers of skin, petrolatum locks that water in by forming an almost-impermeable seal and shea butter lends a buttery finish that smooths rough texture. Petrolatum is considered non-comedogenic despite its thick feel but the formula also contains isopropyl myristate, an oil with a high comedogenic rating. If you are acne-prone that means there is a chance of clogged pores because comedogenic ingredients can trap dead cells inside the follicle. I did not see new breakouts but those with very reactive or oily skin might prefer to patch test first.

Dimethicone and jojoba oil add slip so the cream spreads without tugging while still reinforcing the barrier. Carbomer and triethanolamine form the gel-cream structure and keep the pH comfortable. The preservative system relies on phenoxyethanol, ethylhexylglycerin and glyceryl caprylate which are all broadly considered safe at the low concentrations used here.

Colourants CI 19140, CI 42090 and CI 14700 give the cream its pastel tint. They do nothing for skin health and can occasionally trigger sensitivity in rosacea-prone complexions, something to note if you prefer dye-free formulas.

No lanolin, beeswax or other animal derivatives show up on the INCI so the product is suitable for vegans and vegetarians. As for pregnancy, the absence of retinoids or high-dose salicylic acid makes it relatively low risk but every obstetrician will remind you that topical routines should be cleared with a medical professional first, especially during the first trimester.

One final observation: the jar packaging means vitamin E will gradually oxidise once exposed to air. Keeping the lid tightly closed and storing it away from direct sunlight will stretch its shelf life but if you notice a crayon-like smell it is time to retire the pot.

What I Liked/Didn’t Like

After two weeks of nightly use these are the practical highs and lows I noted

What Works Well:

  • Locks in moisture so skin wakes up plump and comfortable even after central-heating nights
  • Creamy texture spreads easily yet stays put so no greasy imprint on pillowcases
  • Plays nicely with potent serums used the next morning since barrier feels soothed not smothered

What to Consider:

  • Jar packaging exposes vitamin E to air meaning potency can dip before you hit the bottom
  • Contains isopropyl myristate and pastel dyes which may not suit acne-prone or sensitive complexions
  • Hydration is solid but visible glow or line-softening remains modest so some may find results underwhelming

My Final Thoughts

Seven out of ten feels exactly right for Regentiv Oxygenating Night Cream. It is the sort of dependable but not dazzling friend who always remembers to bring snacks to movie night yet never steals the show. If your main objective is to wake up with skin that feels quenched and protected from radiator air or city grit this will do the job with minimal fuss. Those chasing a dramatic brightening effect or wrinkle blurring worthy of a portrait lens may be underwhelmed, in which case a retinoid-laced or peptide-packed formula will scratch that itch more efficiently.

I have worked my way through a small army of overnight treatments over the years so I am comfortable saying I gave this jar a fair shake. For normal to dry skin that values comfort over fireworks it is a safe bet, especially if fragrance and essential oils usually cause you grief. Oily or congestion-prone types might find the isopropyl myristate a gamble and results-hungry skincare magpies may crave more active punch per scoop. Would I recommend it to a close friend? Yes, but with the caveat that they know exactly what they want: a straightforward moisture blanket rather than a multi-tasking powerhouse.

If you want a little more oomph or simply like exploring the night-cream galaxy here are three alternatives I have rotated through my own bedside lineup. Nocturnal Revive Cream by Deascal behaves like a Swiss Army knife for skin, covering hydration barrier support and a gentle brightening lift at a price that does not sting. Water Sleeping Mask by LANEIGE is a feather-light gel that still delivers a satisfying bouncy feel by morning which makes it ideal for combination skin or hot-weather months. Advanced Night Restore by Medik8 leans into ceramides and antioxidants for those who want barrier repair plus an extra shot of environmental defence in one clever pot.

Before you dive in a quick public-service reminder: patch test on the jawline or behind an ear first, sorry to sound like a helicopter parent. Keep expectations realistic, maintain regular use and remember skincare results are like gym gains ‑ stop showing up and they quietly wander off.

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