I Tried “Advanced PDRN Repair Cream” by REJUALL: Here’s My Review

Is REJUALL's overnight treatment worth the money? I used it myself to see.
Updated on: June 19, 2025

Image courtesy of Song of Skin

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REJUALL may not have the same global name recognition as the big legacy houses yet insiders at Seoul’s skin clinics speak of it with the kind of hushed respect usually reserved for cult formulas. The brand positions itself as a premium K-beauty line dedicated to “rejuvenating from all damage,” a lofty claim that instantly piqued my curiosity.

Enter the Advanced Pdrn Repair Cream, a title that sounds equal parts laboratory experiment and futuristic elixir. According to REJUALL, it is a revitalizing night cream for oily, dry and combination skin that promises hydration, glow and overnight firmness via a hefty 1 200 ppm of PDRN plus niacinamide and panthenol. In other words, it is marketed as the one-stop night treatment you never knew you needed.

I gave the cream a full two-week trial, weaving it into my nightly routine to see whether those claims held up in real-world conditions and, more importantly, whether it merits a spot on your vanity.

Disclaimer: This review is neither paid nor sponsored. All thoughts shared here are my own observations. Skin is personal and results can differ based on individual concerns, routines and sensitivities.

What Is Advanced Pdrn Repair Cream?

Advanced Pdrn Repair Cream is a night focused moisturizer from Rejuall that targets multiple skin types including oily dry and combination. It is positioned as a single step finishing product in the evening routine delivering hydration regeneration and a subtle boost in firmness while you sleep. The formula relies on 1 200 ppm of PDRN for visible repair supported by niacinamide panthenol and a gel based texture that aims to feel nourishing yet light.

The cream sits in the overnight treatment category meaning it is designed to work during the skin’s natural nighttime renewal window. Unlike day creams that prioritize sunscreen compatibility or makeup layering an overnight treatment can lean into richer actives and longer absorption times since there is no need to rush out the door. You apply it as the final step on clean dry skin let it soak overnight then rinse or go straight into your morning cleanse. This approach allows actives like PDRN and niacinamide to remain undisturbed for several hours which in theory boosts their efficacy.

Did It Work?

In the spirit of rigorous science I benched my usual overnight treatment for the first three nights of testing so the Advanced Pdrn Repair Cream could take the stage solo. Fourteen days felt like a reasonable window to judge short term performance without drifting into placebo territory.

Night one the gel cream melted in quickly and left a faint silicone slip that vanished within ten minutes. My combination skin woke up looking rested though not wildly different. By the third application I noticed a slight uptick in surface hydration around my nose and no new congestion along the oilier T zone which is already a small victory.

Through the first week the most consistent payoff was comfort: tight post shower dryness stopped nagging before bedtime and stayed quiet till morning. The promised glow took longer. Around day eight I could skip my usual vitamin C on lazy mornings without feeling sallow yet the brightness was more polite than spotlight.

Week two was where results plateaued. The cream kept delivering steady moisture and a soft bouncy feel but the vaunted firmness claim never quite materialized. Fine lines on my forehead looked slightly blurred after a full night’s sleep then reappeared by lunch. No irritation though, even with the niacinamide percentage likely sitting in the mid range.

Overall the formula did what any competent night cream should: hydrate soothe and leave skin even toned by dawn. It did not replace the deeper plumping effect I get from my peptide serum or the glass skin finish of my go to sleeping mask. So while Advanced Pdrn Repair Cream works well enough to earn a respectable seven out of ten I will probably admire it from afar rather than slot it into my permanent lineup.

Main Ingredients Explained

The headline act is PDRN at 1 200 ppm, a DNA fragment usually sourced from salmon that has been shown in clinical wound healing to speed up skin regeneration and calm inflammation. Think of it as a signal booster that tells sluggish cells to repair damage faster. Because it is animal derived the cream is not suitable for vegans or strict vegetarians, although pescatarians may feel comfortable with it.

Supporting PDRN is a familiar K-beauty duo: niacinamide plus panthenol. Niacinamide sits somewhere around the 2-5 percent mark judging by the INCI placement and over two weeks it quietly handled dullness, tempered redness and kept sebum in check. Panthenol works as the soothing counterpart, reinforcing the moisture barrier so hydration stays locked in overnight.

Sodium hyaluronate, glycerin and butylene glycol form the humectant backbone that draws water into the skin then the silicone blend of cyclopentasiloxane, cyclohexasiloxane and dimethicone creates that silky finish people either love or avoid. These silicones rank low on the comedogenic scale, meaning they are unlikely to clog pores for most users, but if you are highly acne prone patch test first. Cetearyl olivate and sorbitan olivate rate around 2 on the same scale so still mild but worth noting.

The gel-cream slip comes from a trio of texture builders: acrylates crosspolymer, polyacrylamide and cellulose gum. They keep the formula lightweight while preventing the water phase from evaporating too quickly. Hydrolyzed collagen offers a temporary plump at the surface however it cannot replace your own collagen deeper down so manage expectations.

No outright pregnancy red flags such as retinoids or high-level salicylic acid appear here but because research on topical PDRN in pregnancy is scarce the safest route is to run the ingredient list by a doctor before use.

Fragrance sits toward the end which explains why the scent disappears after a minute. There is also a small amount of adenosine for wrinkle smoothing and a cocktail of botanical extracts from neem and red algae that round out the antioxidative angle.

Overall the INCI list balances science staples with a few clinic grade touches though the animal origin of PDRN and collagen keeps it off any vegan shelf. Comedogenic risk is low for most skin types, pregnancy use calls for professional clearance and the absence of harsh actives makes the cream relatively safe for nightly use even on sensitive skin.

What I Liked/Didn’t Like

Here is the quick breakdown after two weeks of nightly use.

What Works Well:

  • Refreshing gel-cream texture sinks in fast yet keeps skin comfortably hydrated till morning
  • PDRN, niacinamide and panthenol combo calms redness and delivers a steady, natural looking glow
  • No clogging or stinging on my combination sensitive skin which makes it easy to slot into most routines

What to Consider:

  • Firming effect is subtle so those chasing a dramatic lift may feel underwhelmed
  • Animal sourced PDRN means the formula may not suit vegan users
  • Cool packaging plus a premium price point could be a drawback for shoppers who prefer pumps or budget friendly options

My Final Thoughts

Advanced Pdrn Repair Cream slots neatly into that Goldilocks zone of night moisturisers – not too light, not too rich, respectably science forward yet comfort driven. After two weeks of uninterrupted use I can confirm it behaved like a disciplined straight-A student: always handed in the hydration assignment on time, never talked back, occasionally surprised me with an extra-credit glow but never quite aced the firming pop quiz. I have tested enough overnight treatments to know that a reliable seven out of ten is nothing to sniff at, although it does mean the product will live in my rotation rather than earn valedictorian status.

Who will enjoy it most? Combination or normal-leaning-dry skin types who crave a soothing gel cream that stays put till morning without suffocating pores. Sensitive souls should appreciate the absence of known aggressors while anyone strictly plant based will need to avert their gaze because of the salmon-derived PDRN. If your wish list includes dramatic lifting, heavy resurfacing or a vegan seal you will find more targeted formulas elsewhere.

Would I recommend it to a friend? Yes, with caveats. I would hand it to someone asking for a calming overnight all-rounder and add a friendly heads up that the firmness promise reads louder on the press release than on the face.

If you are shopping around, a few other jars I have emptied might intrigue you. Nocturnal Revive Cream by Deascal is the dependable multitasker that marries rich nourishment with a gentle price tag, suiting every skin personality I have thrown at it. Squalane + Ectoin Overnight Rescue by BIOSSANCE feels like wrapping the complexion in a weightless cocoon and excels at barrier support when winter heaters wreak havoc. Intelligent Retinol Smoothing Night Cream by Medik8 serves a measured dose of retinol for those craving a touch more refinement than PDRN alone can offer without tipping into peeling territory. All three deliver comparable comfort with slightly different extracurricular strengths so choose according to your report card goals.

Before you slather with wild abandon, a few nagging reminders (sorry to play over-protective parent). Patch test behind the ear or on the jaw for a couple of nights, give actives at least a month for full credit and remember that any glow you earn needs regular attendance to stay enrolled. Skin likes consistency, not cramming.

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