2-Bromo-2-Nitropropane-1,3-Diol: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 22, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is 2-Bromo-2-Nitropropane-1,3-Diol?

2-Bromo-2-Nitropropane-1,3-Diol, sometimes called bronopol, is a lab-made compound created from propylene glycol that is treated with nitrous acid then brominated. The result is a white crystalline powder that dissolves well in water and mixes smoothly into creams and gels. Chemists first introduced it in the 1960s while looking for an easy, reliable way to keep personal care products free of harmful microbes. Its success in that role led to fast adoption in skin care, hair care and toiletries.

You will most often see it listed near the bottom of ingredient lists in face moisturizers, serums, cleansers, masks, shampoos and liquid soaps. Because only a small amount is needed to do its job it rarely affects the look or feel of the finished product.

2-Bromo-2-Nitropropane-1,3-Diol’s Cosmetic Benefits/Uses

In cosmetics 2-Bromo-2-Nitropropane-1,3-Diol serves a single but vital purpose as a preservative. It stops the growth of bacteria, yeast and mold in water-based formulas which keeps the product safe and extends its shelf life. Without a preservative many of the lotions and cleansers we rely on every day would spoil within weeks making this ingredient an important guardian of product quality.

Who Can Use 2-Bromo-2-Nitropropane-1,3-Diol

This preservative is generally well tolerated by most skin types including oily, normal, combination and dry because it is used at very low levels and stays dissolved in the water phase of a formula rather than sitting on the skin’s surface. People with very sensitive skin, active eczema or a known allergy to formaldehyde-releasing preservatives may want to steer clear since bronopol can release trace amounts of formaldehyde inside a finished product.

Because 2-Bromo-2-Nitropropane-1,3-Diol is fully synthetic and not derived from animals it fits vegan and vegetarian lifestyles. Ethical status can still vary by brand based on overall animal testing policies so check with the manufacturer if that is a concern.

Current safety assessments show no special restrictions for use during pregnancy or breastfeeding when the ingredient is present at the legally allowed concentrations. Absorption through intact skin is minimal yet this is not medical advice and anyone pregnant or nursing should review their skin care routine with a doctor before use just to be safe.

The ingredient does not increase photosensitivity so it will not make skin more likely to burn in the sun. No other major lifestyle or product conflicts are known beyond the sensitivity issues mentioned above.

Potential Side Effects/Adverse Reactions

Reactions to topical 2-Bromo-2-Nitropropane-1,3-Diol vary from person to person. The following are potential side effects that have been noted in the scientific literature yet they are uncommon in everyday use when the ingredient is included at permitted levels.

  • Skin irritation mild stinging or burning can occur especially on compromised skin
  • Contact dermatitis red itchy patches in people already sensitized to bronopol or to formaldehyde-releasing preservatives
  • Allergic reaction rare cases of swelling hives or blistering
  • Eye irritation tearing or redness if the product accidentally gets into the eyes
  • Cross-reaction with other formaldehyde donors increased chances of sensitivity for users already allergic to imidazolidinyl urea DMDM hydantoin or similar ingredients

If any of these effects occur stop using the product immediately and consult a healthcare professional for guidance.

Comedogenic Rating

Rating: 0/5

2-Bromo-2-Nitropropane-1,3-Diol is fully water soluble and used at very small concentrations so it does not leave an oily film that could clog pores. For that reason it sits at the bottom of the scale for causing breakouts.

This makes the ingredient generally suitable for acne-prone or congested skin.

No studies link it to worsening blackheads or whiteheads and its quick rinse-off in cleansers and shampoos further lowers any risk.

Summary

2-Bromo-2-Nitropropane-1,3-Diol is a preservative that keeps bacteria, yeast and mold out of water-based beauty products. It works by slowly releasing small amounts of active agents that damage microbial cells so lotions, gels and shampoos stay safe and fresh for months.

While once a staple in many mainstream formulas its use has dipped as brands explore newer options yet it still appears in a fair number of cleansers hand soaps and travel-friendly products that need strong protection.

Safety reviews find it low risk for most users when kept within legal limits though very sensitive skin can react. As with any new ingredient a quick patch test on a small area helps catch problems early and keeps your routine worry free.

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