3-Ethylamino-P-Cresol Sulfate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 22, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is 3-Ethylamino-P-Cresol Sulfate?

3-Ethylamino-P-Cresol Sulfate is a lab-made ingredient created by joining a modified form of cresol, a small aromatic molecule, with ethylamine and then pairing the result with a bit of sulfuric acid to form a stable salt. This salt structure keeps the ingredient water-friendly so it blends smoothly into hair care formulas.

The compound first drew attention in the mid-1900s when chemists were searching for agents that could soften hair after harsh coloring steps. They noticed that this cresol-based salt left strands easier to comb and gave a healthy look, so it soon found a place in rinse-off conditioners and salon treatments. Today it is produced in large batches through a straightforward three-step process: react p-cresol with ethylamine, purify the resulting ethylamino cresol, then neutralize it with food-grade sulfuric acid and dry it into a fine powder.

You will mostly spot 3-Ethylamino-P-Cresol Sulfate in leave-in or rinse-off conditioners, repair masks, color-care creams and smoothing serums aimed at taming frizz or boosting shine. It is rarely used in skin products and is not found in makeup.

3-Ethylamino-P-Cresol Sulfate’s Cosmetic Benefits/Uses

When added to hair products this ingredient serves one main purpose.

Hair conditioning: The sulfate salt carries a mild positive charge that is attracted to the slightly negative surface of hair fibers. It forms a thin, even layer that smooths raised cuticles, reduces static and helps each strand glide against the next, making detangling easier. With the cuticle lying flat light bounces off more evenly, so hair looks shinier and feels softer from root to tip.

Who Can Use 3-Ethylamino-P-Cresol Sulfate

This conditioner is gentle enough for all hair and scalp types, including dry, oily, color treated and sensitive. Because it stays mainly on the outer surface of hair and is rinsed or left on in small concentrations, it seldom poses problems for most skin types either.

The molecule is fully synthetic and does not rely on animal by-products so it fits vegan and vegetarian lifestyles. Its production process is also free of common animal-derived processing aids such as gelatin filters or tallow based surfactants.

No specific warnings exist for pregnant or breastfeeding women when the ingredient is used in rinse-off or leave-in products. Systemic absorption is expected to be minimal, yet this is not medical advice and anyone who is pregnant or nursing should confirm suitability with a physician before adding new hair care products to their routine.

3-Ethylamino-P-Cresol Sulfate is not known to cause photosensitivity and does not interact with sunlight, so there is no added need for sun protection beyond normal habits.

Potential Side Effects/Adverse Reactions

Reactions to topical 3-Ethylamino-P-Cresol Sulfate vary from person to person. The points below cover potential issues only. When used at the low concentrations typical of hair products most users experience none of these effects.

  • Mild scalp irritation such as itching or redness in very sensitive individuals
  • Contact allergy presenting as small bumps or rash
  • Eye stinging or watering if the product accidentally runs into the eyes
  • Product buildup that can leave hair feeling heavy if not rinsed thoroughly

If any unwanted effect occurs discontinue use and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 0/5. 3-Ethylamino-P-Cresol Sulfate is a small, water soluble salt that rinses off easily and does not leave an oily film on skin. Because it lacks heavy lipids or waxes it is very unlikely to clog pores, so it earns a zero on the comedogenic scale.

Those prone to acne or breakouts can generally use products containing this ingredient without added concern.

Since it is almost always found in hair care products that are kept on the hair shaft rather than massaged into facial skin, real-world exposure to pore linings is minimal.

Summary

3-Ethylamino-P-Cresol Sulfate is a lab made hair conditioner that smooths cuticles, reduces static and boosts shine by depositing a thin positively charged layer along each strand. Its water friendly sulfate form helps it disperse evenly and rinse clean without heaviness.

The ingredient sees moderate use, mainly in specialized shampoos, masks and color care lines, while more common quats still dominate mass market formulas.

Safety data show low irritation potential, negligible absorption and no comedogenicity, making it suitable for most users. As with any new cosmetic though, do a quick patch test first to confirm personal tolerance.

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