Acetone: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Acetone?

Acetone is a clear, highly volatile liquid belonging to the ketone family of organic compounds. It occurs naturally in small amounts in the human body, trees and some fruits, yet most of the acetone used in cosmetics is produced synthetically for consistency and purity. Modern manufacturing relies on the cumene process, where benzene and propylene react to form cumene that is later oxidized and split into acetone and phenol; the result is a stable ingredient that meets cosmetic grade standards.

The cosmetic world adopted acetone in the early twentieth century when formulators realized its swift ability to dissolve oils, resins and film formers. Nail technicians were among the first to embrace it for efficient polish removal. Today you will find acetone in nail polish removers, nail prep pads, some quick-dry top-coats, fragrance concentrates and certain aerosol styling or cleansing sprays where rapid evaporation is desired.

Acetone’s Cosmetic Benefits/Uses

Below are the roles acetone can play in a formulation and the advantages each role provides.

  • Denaturant: Acetone can be added to cosmetic alcohols to make them unfit for drinking, helping brands comply with regulations while keeping consumer costs lower.
  • Fragrance: In small amounts acetone lends a crisp, slightly sweet scent and also helps disperse aromatic oils evenly, giving perfumes or scented polishes a balanced initial impression.
  • Solvent: Its fast-acting dissolving power breaks down oils, pigments and polymers, making it invaluable for removing nail lacquer, cleaning brushes and thinning viscous formulas so they spread smoothly then flash off without residue.

Who Can Use Acetone

Acetone suits most skin types when used briefly and in low concentrations, though very dry or sensitive skin can feel tight or irritated because the solvent strips natural oils. Oily or resilient skin usually tolerates it well, and it will not clog pores for acne-prone users.

The ingredient is vegan and vegetarian friendly as the cosmetic grade material is synthesized from petrochemical feedstocks, with no animal-derived additives or processing aids.

For pregnant or breastfeeding individuals, topical exposure from nail polish removers or similar products is considered low risk thanks to rapid evaporation and minimal skin penetration. This is not medical advice, and anyone expecting or nursing should confirm product use with a healthcare professional.

Acetone does not make skin more sensitive to sunlight and has no known phototoxic effects. Keep in mind its high flammability and strong odor, so use it in a well-ventilated space away from open flames.

Potential Side Effects/Adverse Reactions

Responses to topical acetone vary from person to person. The points below list potential but uncommon side effects. When products are formulated and used correctly most people will experience none of these issues.

  • Dryness and tightness
  • Stinging or burning sensation, especially on broken skin
  • Redness or inflammation in sensitive areas
  • Cracking or peeling with repeated, prolonged exposure
  • Allergic contact dermatitis in rare cases
  • Dizziness or headache from inhaling concentrated vapors during extended use

If any discomfort or adverse reaction occurs stop using the product immediately and consult a medical professional.

Comedogenic Rating

Rating: 0/5 (non-comedogenic)

Acetone flashes off the skin within seconds and leaves no film or residue that could block pores. It contains no oils or waxes and does not interact with sebum, which is why it earns the lowest possible comedogenic score.

Because it poses virtually no risk of clogging pores this solvent is generally considered suitable for people who are prone to acne or breakouts.

Its rapid evaporation means it is rarely left on the skin for long, further reducing any chance of pore problems. That said, very frequent use might over-dry the skin which can sometimes trigger rebound oiliness in some individuals.

Summary

Acetone acts in formulas as a denaturant to render alcohol undrinkable, a fragrance aid that gives a quick fresh opening note, and above all a solvent that dissolves stubborn varnishes, oils and resins then evaporates cleanly. These abilities make it a staple in nail polish removers, prep pads and certain fast-dry cosmetic sprays.

While not the trendiest ingredient on the market its sheer effectiveness keeps it popular in professional nail salons and DIY manicure kits alike.

Topical use is considered safe for most people when products are applied as directed, though its strong drying action can irritate very sensitive or already compromised skin. As with any new product it is wise to perform a quick patch test first to be sure your skin reacts well.

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