Acetylated Hydrogenated Lanolin: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Acetylated Hydrogenated Lanolin?

Acetylated Hydrogenated Lanolin is a specially processed form of lanolin, the natural waxy substance obtained from sheep’s wool. Regular lanolin is rich in fatty acids that closely resemble the skin’s own lipids. To make it more stable and pleasant to use, manufacturers first hydrogenate lanolin, which means they add hydrogen to its fatty acids. This step helps reduce odor and improve shelf life. The hydrogenated lanolin is then acetylated, a reaction that attaches acetate groups to its structure, giving the ingredient a lighter feel and better spreadability on skin.

Lanolin has been valued for skin care since the late 1800s, but early forms could feel greasy or have a strong scent. Advances in chemistry during the mid-20th century led to hydrogenated and acetylated versions that kept the original moisturizing power while making the material more cosmetically elegant. Today, Acetylated Hydrogenated Lanolin appears in many leave-on and rinse-off products, including face creams, body lotions, hand balms, lip balms, makeup primers, tinted moisturizers, hair styling waxes and barrier creams aimed at very dry or rough skin.

Acetylated Hydrogenated Lanolin’s Cosmetic Benefits/Uses

In formulas, Acetylated Hydrogenated Lanolin offers two main functions that enhance both product performance and user experience:

  • Skin conditioning – forms a soft, flexible film that helps keep water in the outer skin layers so skin feels supple and comfortable
  • Emollient – fills in tiny gaps between skin cells to smooth rough patches and give products a rich, silky glide during application

Who Can Use Acetylated Hydrogenated Lanolin

This ingredient suits most people with normal, dry or mature skin because its rich fatty acid profile helps lock in moisture and soften rough areas. Those with very oily or acne-prone skin may find it too occlusive and could notice clogged pores or breakouts, so lighter emollients might be better for them.

Because it is sourced from sheep wool it is not considered vegan friendly. Vegetarians who are comfortable with wool-derived ingredients may still choose to use it.

Current research shows no specific concerns for topical use during pregnancy or while breastfeeding. Still, this is not medical advice and anyone who is pregnant or nursing should have a doctor review any skincare products they plan to use.

Acetylated Hydrogenated Lanolin does not increase sensitivity to sunlight so it will not make skin more prone to sunburn. People with a known lanolin or wool allergy, however, should avoid it to prevent an allergic flare-up.

Potential Side Effects/Adverse Reactions

Responses to Acetylated Hydrogenated Lanolin vary from person to person. The following list covers possible side effects, but most users will not encounter them when the ingredient is formulated and used correctly.

  • Contact allergy – redness, swelling or rash in those sensitive to lanolin
  • Pore clogging – whiteheads or blackheads in individuals prone to acne
  • Skin irritation – mild stinging or burning on compromised or very sensitive skin
  • Folliculitis – inflamed hair follicles from trapped bacteria under an occlusive film
  • Eye irritation – watering or stinging if the product migrates into the eyes

If any of these issues appear stop using the product and seek advice from a qualified healthcare professional.

Comedogenic Rating

Rating: 2 / 5

Acetylated Hydrogenated Lanolin sits in the low-to-moderate range because its waxy fatty acids can block pores in some users yet the acetylation step reduces greasiness compared with raw lanolin. Most people with balanced or dry skin experience no issues, but those who break out easily might notice congestion, especially if the product is left on skin for long hours or layered under heavy makeup. The rating can shift upward if the final formula is thick or paired with other occlusives, so the full product context matters.

Bottom line: not the best choice for acne-prone skin, though many tolerate it without trouble.

Summary

Acetylated Hydrogenated Lanolin is prized for two core jobs: conditioning skin and acting as an emollient. Its fatty acid profile mimics the skin’s own lipids so it fills microscopic gaps between cells, smooths rough texture and slows water loss to keep skin soft. The added hydrogen and acetate groups lighten the feel, boost stability and cut down on the distinctive lanolin scent, making it easier to blend into modern creams, balms and even some makeup.

While not as trendy as plant oils or silicone alternatives, this refined lanolin derivative still shows up in many rich moisturizers and lip products aimed at dry skin where its cushioning, long-lasting moisture is hard to beat. Safety data are solid with only isolated allergy or clogging concerns. Most users can enjoy it worry-free but, as with any new skincare ingredient, patch test first to ensure your individual skin stays happy.

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