Agastache Rugosa Callus Culture: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Agastache Rugosa Callus Culture?

Agastache Rugosa Callus Culture is an extract obtained from the lab-grown cells of Korean mint, a fragrant herb in the Lamiaceae family. In the wild the plant has long been valued in East Asia for its fresh aroma and calming tea, qualities that inspired researchers to explore it for skin care. To create the ingredient technicians take tiny pieces of the plant and place them in a nutrient-rich medium, prompting the cells to multiply into a soft mass called a callus. These cells are then filtered and blended into a water or glycerin base, yielding a stable extract free from seasonal or environmental fluctuations. Thanks to its gentle nature and skin-friendly profile the extract is now found in lightweight serums, soothing masks, daily moisturizers, anti-aging creams and post-procedure treatments.

Agastache Rugosa Callus Culture’s Cosmetic Benefits/Uses

In formulas Agastache Rugosa Callus Culture serves as a skin-conditioning agent, meaning it helps keep skin soft, supple and balanced. By supporting the skin barrier and adding a touch of moisture it can enhance overall comfort, leaving the complexion looking smoother and more refreshed.

Who Can Use Agastache Rugosa Callus Culture

This gentle extract is generally suitable for all skin types including dry, oily and combination. Its soothing profile makes it especially helpful for sensitive or easily irritated skin, as it does not contain the volatile oils that can sometimes trigger redness in essential oil–rich botanicals. No particular skin type is known to react poorly to it, though anyone with a documented mint allergy should approach with caution.

Because the material is grown entirely from plant cells in a controlled setting and no animal-derived agents are used in the process, products featuring Agastache Rugosa Callus Culture are appropriate for both vegans and vegetarians.

Current data suggests the ingredient is mild and non systemic, so it should be fine for pregnant or breastfeeding women when applied topically. That said this is not medical advice and expecting or nursing mothers should always clear any skincare routine with a healthcare provider before use.

The ingredient does not increase photosensitivity and can be used both day and night without raising the risk of sun-related irritation. It also plays well alongside common actives like niacinamide or hyaluronic acid, making it easy to slot into most routines.

Potential Side Effects/Adverse Reactions

Side effects from topical Agastache Rugosa Callus Culture differ from person to person. The points below outline potential reactions, but they are uncommon when the ingredient is properly formulated and most users will not notice any problems.

  • Mild stinging or tingling
  • Temporary redness at the application site
  • Itchiness or dryness in very sensitive individuals
  • Allergic contact dermatitis in those with mint family allergies

If any adverse reaction occurs stop using the product and consult a medical professional for guidance.

Comedogenic Rating

Rating: 0 / 5

Agastache Rugosa Callus Culture is supplied in a light water or glycerin base and contains virtually no oils or waxes that could block pores. The molecule size and hydrophilic nature make it unlikely to linger inside follicles or mix with sebum, so it earns the lowest comedogenic score.

Because of this it is considered suitable for acne-prone or breakout-prone skin.

Only the finished formula can determine clogging potential, so if the product also contains heavy butters or silicones its overall rating could shift upward.

Summary

Agastache Rugosa Callus Culture primarily acts as a skin-conditioning agent, keeping the surface soft, hydrated and comfortable by supporting the moisture barrier. The lab-grown cells provide consistent levels of beneficial plant compounds while avoiding the essential oils that can irritate delicate skin.

Although not yet a mainstream buzzword, the ingredient is slowly gaining fans among formulators who want a gentle botanical that plays nicely with actives and fits clean beauty claims.

Current data shows it is low risk for irritation or clogging. Still, skin can be unpredictable so it is wise to patch test any new product that features this extract before full-face use.

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