Ampelopsis Grossedentata Leaf Extract: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Ampelopsis Grossedentata Leaf Extract?

Ampelopsis Grossedentata Leaf Extract comes from the leaves of Ampelopsis grossedentata, a climbing plant in the grape family that grows mainly in the warm mountain areas of China and Southeast Asia. The leaves are packed with plant compounds called flavonoids, the most talked about one being dihydromyricetin, which is known for its strong antioxidant power. For hundreds of years locals brewed the leaves as a herbal tea to cool the body and ease discomfort, a tradition that drew the attention of modern skin-care scientists looking for gentle botanical ingredients.

To make the extract, farmers pick the leaves when their flavonoid content is at its peak. The leaves are then dried and crushed before going through a water or water-glycol soak that pulls out the active compounds. The liquid is filtered, concentrated and refined to meet cosmetic grade standards. The finished extract is a light amber liquid or fine powder that blends well with both water-based and some oil-based formulas.

Thanks to its soothing and antioxidant qualities, Ampelopsis Grossedentata Leaf Extract is now found in a range of leave-on and rinse-off products. You will see it in daily moisturizers, anti-aging serums, calming masks, after-sun gels and toners aimed at sensitive or redness-prone skin.

Ampelopsis Grossedentata Leaf Extract’s Cosmetic Benefits/Uses

This plant extract brings mainly one care-boosting feature to a formula.

Skin conditioning: The flavonoid-rich extract helps soften and smooth the skin surface while supporting its natural moisture barrier. Its antioxidant content also fights free radicals caused by sun and pollution, which can make the skin look tired or dull. Formulas that use the extract often feel soothing on application making it a good pick for products that promise comfort and daily defense.

Who Can Use Ampelopsis Grossedentata Leaf Extract

The extract is gentle enough for most skin types, including dry, normal, combination and oily. Its light texture and antioxidant profile can be especially helpful for sensitive or easily flushed skin since it brings a calming feel without heavy oils or fragrances. There are no known reasons to avoid it if you have acne-prone skin as it does not clog pores or add excess oil.

Ampelopsis Grossedentata Leaf Extract is plant based with no animal derivatives, which makes it suitable for vegans and vegetarians. Production typically relies on water or plant-derived glycols for extraction rather than animal solvents.

Current data shows no specific concerns for pregnant or breastfeeding women when the extract is used topically in normal cosmetic amounts. Still, this is not medical advice. Anyone who is pregnant or nursing should review any skin care product with a qualified health professional to be safe.

The ingredient does not increase photosensitivity so it will not make skin more prone to sunburn. Standard daytime sun protection is still smart practice.

Potential Side Effects/Adverse Reactions

Responses to topical Ampelopsis Grossedentata Leaf Extract can vary from person to person. The points below list potential issues even though most users experience none of them when the ingredient is properly formulated and used as directed.

  • Mild redness or stinging in very sensitive skin, usually short lived and rare
  • Allergic contact dermatitis in individuals with an allergy to grape family plants or specific flavonoids
  • Interaction with strong actives such as high levels of acids or retinoids that may already irritate the skin, potentially compounding sensitivity

If you notice any persistent irritation discontinue use and consult a healthcare professional

Comedogenic Rating

Rating: 0 / 5

Ampelopsis Grossedentata Leaf Extract is almost entirely made up of water-soluble flavonoids with virtually no oils, waxes or fatty acids that could block pores, so it earns the lowest possible score. In most formulations it is added at low percentages and is often dissolved in water or light glycols, which further limits any pore-clogging potential. Because of this it is considered suitable for skin that is prone to acne or breakouts. As always the final product matters too, so a heavy cream containing the extract can still feel greasy even if the extract itself is not.

Summary

Ampelopsis Grossedentata Leaf Extract is mainly valued for skin conditioning. Its rich supply of flavonoids helps neutralize free radicals, support the skin barrier and leave the surface feeling soft and calm. Antioxidant action defends against the dulling effects of sun and pollution while the soothing nature of the plant makes it a welcome addition to products aimed at sensitive or stressed skin.

Although not as famous as green tea or chamomile this extract is quietly gaining traction in modern formulas, especially in Asia-inspired brands that highlight traditional botanicals. You will spot it most often in lightweight gels, toners and day creams that market themselves as gentle yet protective.

Current research and consumer use suggest Ampelopsis Grossedentata Leaf Extract is low risk with minimal chances of irritation or pore congestion. Still, skin is personal so it is wise to patch test any new product that contains the extract before applying it to your entire face.

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