Avenanthramides: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Avenanthramides?

Avenanthramides are natural compounds found almost exclusively in oats. Chemically they are a group of phenolic acids that give oats much of their soothing power. Although scientists have known about them since the 1980s, skin-care brands started spotlighting them in the early 2000s after research showed their calming and antioxidant traits.

To get avenanthramides for cosmetics, manufacturers start with high-quality oat kernels. The oats are cleaned, ground and mixed with food-grade solvents that pull the active molecules out of the grain. The liquid extract is then filtered, concentrated and gently dried into a fine powder that can be blended into creams, lotions or serums.

You will most often see avenanthramides in products aimed at calming or protecting the skin. Common formats include soothing face masks, daily moisturizers for sensitive skin, after-sun gels, anti-aging serums and scalp treatments that target irritation or dryness.

Avenanthramides’s Cosmetic Benefits/Uses

Formulators reach for avenanthramides because they pack several skin-friendly talents into one ingredient.

  • Antioxidant – They neutralize free radicals that come from UV light and pollution. This helps slow the look of premature aging like fine lines and dullness
  • Hair Conditioning – When added to shampoos or leave-in sprays they coat the hair shaft, making strands feel softer and look smoother while easing scalp discomfort
  • Skin Protecting – Avenanthramides calm redness and itch by blocking signals that trigger irritation. This makes them ideal for sensitive or freshly shaved skin and helps reinforce the skin’s barrier so it holds on to moisture longer

Who Can Use Avenanthramides

Avenanthramides are gentle enough for all skin types, including oily, dry, combination and especially sensitive or eczema-prone skin. Those with a confirmed oat allergy should steer clear since the ingredient is extracted from oats and could trigger a reaction.

Because avenanthramides are plant derived and processed without animal by-products, they are suitable for vegans and vegetarians.

Current research shows no specific risks for pregnant or breastfeeding women when using avenanthramide-containing products. This is not medical advice and anyone who is pregnant or nursing should check with a healthcare professional before adding new skincare just to be safe.

The ingredient does not cause photosensitivity; in fact its antioxidant action can help defend skin against sun-induced free radicals. It can be used morning or night and pairs well with daily sunscreen.

Potential Side Effects/Adverse Reactions

Side effects from topical avenanthramides vary from person to person. The following are potential reactions and remain uncommon when the ingredient is properly formulated.

  • Allergic contact dermatitis – rare redness, itching or rash in people sensitive to oats
  • Mild stinging or burning – usually temporary and more likely on compromised or freshly exfoliated skin
  • Eye irritation – watering or discomfort if product accidentally gets into the eyes
  • Hives or swelling – very uncommon but possible in those with severe oat or grain allergies

If any of these reactions occur stop using the product and consult a healthcare professional.

Comedogenic Rating

Rating: 0 (non-comedogenic)

Avenanthramides are small water-soluble molecules that do not leave an oily film on the skin or clog pores. They absorb quickly, have no waxy residues and are typically used at low concentrations, so the risk of blocking follicles is minimal.

Suitable for acne-prone or breakout-prone skin.

Avenanthramides are usually delivered in light emulsions or gels, which further lowers the chance of pore congestion compared with heavy creams.

Summary

Avenanthramides bring three standout benefits: antioxidant power that fights free radicals, skin protecting action that calms redness and reinforces the barrier and hair conditioning properties that smooth strands and soothe the scalp. They achieve these effects by neutralising unstable molecules and modulating the signals that drive irritation.

While oats are a household name, the specific avenanthramide fraction is less of a buzzword, yet its use is quietly growing in sensitive skin formulas and after-sun products.

Overall avenanthramides are considered very safe for topical use, with side effects rare except in people who have oat allergies. As with any new skincare ingredient it’s wise to perform a small patch test first to check for personal sensitivity.

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