Beta-Glucan: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Beta-Glucan?

Beta-Glucan is a long chain of glucose molecules that link together in patterns known as β(1-3), β(1-4) and β(1-6). These links give the polysaccharide its thick, gel-like feel and its ability to hold water. Most cosmetic-grade Beta-Glucan is sourced from oats, barley or certain types of yeast, although some manufacturers obtain it from fungi such as mushrooms. Interest in Beta-Glucan began in the 1960s when scientists noticed that oat-based poultices soothed irritated skin. Over time, extraction techniques improved, allowing the ingredient to be isolated in pure form for creams and serums.

To make Beta-Glucan for skincare, producers first mill the raw plant or yeast material, then use water or mild solvents to separate the polysaccharide. The extract is filtered, concentrated and dried into a fine powder that dissolves easily in water-based formulas. Thanks to its moisturizing and texturizing qualities, Beta-Glucan shows up in sheet masks, hydrating toners, anti-aging creams, soothing after-sun gels, barrier-repair ointments and even some makeup primers.

Beta-Glucan’s Cosmetic Benefits/Uses

Formulators choose Beta-Glucan because it delivers more than one practical benefit in a skin care product.

  • Bulking: Adds desirable thickness and body, creating a rich, cushiony feel without relying on heavy oils or waxes. This helps stabilize watery gels and lotions so they spread smoothly and stay in place.
  • Skin Conditioning: Forms a lightweight film that pulls water to the surface of the skin, leaving it soft and plump. It can also calm temporary redness and support the skin barrier, making it useful in products aimed at sensitive or mature skin.

Who Can Use Beta-Glucan

Beta-Glucan is gentle enough for almost every skin type. Dry, sensitive, mature and even combination skin can benefit from its water-binding and soothing feel. Very oily skin can use it too because the ingredient itself is light and non-greasy, although the overall formula still matters.

The ingredient is usually sourced from oats, barley, yeast or mushrooms, none of which come from animals, so Beta-Glucan is considered suitable for vegans and vegetarians. Anyone who follows a plant-based lifestyle can feel comfortable using products that feature it, provided the rest of the formula also meets their standards.

No studies show problems for women who are pregnant or breastfeeding when Beta-Glucan is used on the skin. Because every pregnancy is unique, this is not medical advice and expectant or nursing mothers should run any skincare product past their doctor just to be on the safe side.

Beta-Glucan does not make skin more sensitive to sunlight, so it does not raise the risk of sunburn. It also plays well with most other common skincare ingredients such as vitamin C, niacinamide and retinol.

Potential Side Effects/Adverse Reactions

Side effects from topical Beta-Glucan differ from person to person. The points below cover potential reactions, but most users will not notice any problems when the ingredient is used at normal amounts in a well-made product.

  • Allergic contact dermatitis – rare itching, redness or rash in people who are sensitive to oats, barley or yeast
  • Mild stinging or burning – can occur if the skin barrier is already damaged or highly reactive
  • Breakouts – unlikely but possible if the overall formula is heavy or occlusive on acne-prone skin
  • Fungal acne flare – very uncommon yet possible in those prone to malassezia issues since the polysaccharide could act as a food source

If any of these effects show up stop using the product and consult a healthcare professional or dermatologist

Comedogenic Rating

Rating: 1 out of 5. Beta-Glucan is a large water-soluble sugar molecule that does not sink into pores the way oils or waxes can. It forms a lightweight surface film that holds moisture rather than clogging follicles, which is why it earns a very low score.

This makes the ingredient generally suitable for people who are prone to acne or breakouts. The only caveat is that a finished product’s overall formula can still be problematic if it contains heavier emollients or occlusives.

Because Beta-Glucan may act as a minor food source for malassezia, a tiny number of users with fungal acne could react, though this is uncommon.

Summary

Beta-Glucan serves mainly as a bulking and skin-conditioning agent. Its long chain structure thickens watery formulas, giving creams and gels a plush feel, while its film-forming ability attracts and locks in water to keep skin soft and calm.

The ingredient has grown steadily more popular thanks to the current focus on barrier support and hydration, though it is still less talked about than hyaluronic acid.

Topical use is considered very safe with few reported reactions. Still, it is wise to patch test any new product that contains Beta-Glucan to make sure your skin agrees with the full formula.

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