Bifida/Nonfat Milk Ferment Lysate Filtrate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Bifida/Nonfat Milk Ferment Lysate Filtrate?

Bifida/Nonfat Milk Ferment Lysate Filtrate comes from nonfat milk that has been fermented with the friendly bacterium Bifidobacterium longum. During fermentation the bacteria break down milk proteins and sugars into smaller parts like peptides, amino acids and vitamins. Afterward the mix is gently broken open, or lysed, to release the inner contents of the bacteria, then filtered to remove large particles. The result is a clear liquid rich in nutrients and bioactive fragments that can be easily absorbed by skin.

Skin care brands became interested in this ingredient after seeing how traditional fermented foods helped keep skin calm and supple. Early Korean and Japanese beauty companies began adding milk ferments to lotions in the late 1990s, and research followed showing improved hydration and comfort. Modern processing methods now allow large-scale production that meets cosmetic safety standards.

The filtrate is most often blended into leave-on products where its skin-loving components can stay in contact with the surface. You will find it in lightweight essences, sheet masks, serums, anti-aging creams, soothing moisturizers and eye treatments. Because it is water-soluble it pairs well with gels and emulsions and does not affect a formula’s texture or scent.

Bifida/Nonfat Milk Ferment Lysate Filtrate’s Cosmetic Benefits/Uses

In formulas this ingredient serves one main purpose: skin conditioning. It helps skin feel softer, smoother and more balanced by supporting the surface barrier, drawing in moisture and supplying small nutrients that tired or stressed skin can use. Over time regular use can lead to a healthier-looking complexion with less dryness and visible irritation.

Who Can Use Bifida/Nonfat Milk Ferment Lysate Filtrate

This ferment filtrate is gentle and water based so it suits most skin types including dry, sensitive, combination and oily skin. Its soothing nature makes it a good pick for skin that flushes easily or feels tight. People with a known milk or lactose allergy should proceed with caution since trace proteins from dairy could remain in the finished ingredient, even though the chance of reaction is low.

Because the source material is nonfat milk, the ingredient is not suitable for vegans. It is vegetarian friendly since no animal is harmed in the process and dairy is permitted in a vegetarian lifestyle.

Current data shows no specific risks for women who are pregnant or breastfeeding when the ingredient is used topically at cosmetic levels. This is not medical advice and anyone expecting or nursing should check with a doctor before starting any new skincare product just to be safe.

The filtrate does not increase sensitivity to sunlight, so special daytime precautions are not needed beyond normal daily sunscreen use. It also plays well with common actives like vitamin C, niacinamide and retinoids, making it easy to slot into most routines.

Potential Side Effects/Adverse Reactions

Responses to topical Bifida/Nonfat Milk Ferment Lysate Filtrate differ from person to person. The following points list potential side effects, but they are uncommon when the ingredient is formulated and used as intended.

  • Mild redness or stinging
  • Localized itching
  • Hives or rash in individuals with a milk allergy
  • Breakouts in very acne prone skin if the overall formula is heavy or occlusive
  • Contact dermatitis in rare cases of heightened sensitivity

If any of these effects occur stop using the product and seek guidance from a healthcare professional.

Comedogenic Rating

Rating: 0–1

Bifida/Nonfat Milk Ferment Lysate Filtrate is water based, contains no heavy oils or waxes and absorbs quickly, so it has little tendency to block pores. Any lingering dairy peptides are highly soluble and rinse away easily, keeping residue minimal. Because the raw material is used at low percentages and remains lightweight, most experts place it at the very bottom of the comedogenic scale.

Suitable for acne-prone or breakout-prone skin.

Keep in mind that the overall formula matters; if the product also contains rich emollients it could still feel heavy despite this ingredient’s low rating.

Summary

Bifida/Nonfat Milk Ferment Lysate Filtrate is a gentle skin-conditioning agent that helps reinforce the surface barrier, improve moisture retention and soothe visible irritation thanks to its mix of peptides, amino acids and vitamins created during fermentation. These small molecules are readily accepted by the skin, making the ingredient an efficient hydrator and comfort booster.

While not as famous as hyaluronic acid or niacinamide, it enjoys steady popularity in Korean and Japanese formulas and is gaining attention in Western serums and essences for its barrier-friendly reputation.

Topical use is considered very safe for the general population with only rare reports of sensitivity, mainly among those with milk allergies. As with any new skincare ingredient, patch test first to confirm compatibility.

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