What Is Bis-Hexacosyl Dimethicone?
Bis-Hexacosyl Dimethicone is a silicone-based ingredient created by bonding dimethicone with two long chains of hexacosyl groups, each containing 26 carbon atoms. This pairing gives the molecule its silky texture and water-resistant character, qualities that make silicones popular in modern skin care. Silicones entered cosmetics in the 1950s for their smooth feel and protective finish, and chemists have since modified them to fine-tune performance. Bis-Hexacosyl Dimethicone is produced through a controlled reaction that links high-purity dimethicone with fatty alcohol chains, followed by purification steps that remove unreacted materials and ensure cosmetic-grade quality.
Because it forms a flexible, breathable film on the skin, Bis-Hexacosyl Dimethicone is often included in moisturizers, night creams, anti-aging serums, hydrating masks, soothing lotions and even some makeup primers. Its velvety glide helps formulas spread evenly while leaving a soft, non-greasy afterfeel.
Bis-Hexacosyl Dimethicone’s Cosmetic Benefits/Uses
This ingredient brings multiple texture-enhancing perks to a formulation.
- Skin Conditioning – It forms a lightweight barrier that helps hold moisture on the skin surface, improving softness and reducing the appearance of dryness.
- Emollient – Its smooth, cushiony touch fills in tiny surface gaps so skin feels silky and looks more even, which can boost the overall sensory appeal of creams and lotions.
Who Can Use Bis-Hexacosyl Dimethicone
Bis-Hexacosyl Dimethicone works well for most skin types including dry, normal and combination skin because its breathable film helps trap moisture without feeling heavy. Oily or acne-prone users usually tolerate it too since the molecule is large and tends to sit on the surface rather than sinking into pores however those who notice that rich silicones trigger breakouts may prefer lighter textures.
The ingredient is produced from synthetic silicone and plant-derived fatty alcohols, so it is suitable for vegans and vegetarians. No animal by-products or animal testing are required for its manufacture by reputable suppliers.
Current research shows no specific risks for people who are pregnant or breastfeeding when Bis-Hexacosyl Dimethicone is applied topically in cosmetic concentrations. This is not medical advice and anyone who is expecting or nursing should review all skincare products with a qualified healthcare provider to be safe.
The compound does not make skin more sensitive to sunlight and it has no known phototoxic effects. It is odorless and colorless, making it unlikely to interfere with fragranced or tinted formulas.
Potential Side Effects/Adverse Reactions
Side effects from topical Bis-Hexacosyl Dimethicone vary between individuals. The points below outline potential reactions only and most users will not experience them when the ingredient is used correctly in a well-formulated product.
- Mild pore congestion or breakout in those extremely prone to silicone buildup
- Rare contact dermatitis presenting as redness, itching or swelling
- Stinging or warmth if applied to broken or highly compromised skin
- Interaction with highly occlusive products that can create an overly heavy feel on very oily skin
If any discomfort or irritation occurs stop using the product and seek advice from a healthcare professional.
Comedogenic Rating
Rating: 1/5. Bis-Hexacosyl Dimethicone sits mostly on the skin surface, forms a breathable film and has a large molecular size that makes it unlikely to wedge into pores, so it earns a low score. Most acne-prone users can use it without issues, though exceptionally clog-sensitive skin might still prefer lighter textures. Because this silicone is typically blended at modest levels and is easy to wash off with a standard cleanser, the risk of persistent buildup is minor.
Summary
Bis-Hexacosyl Dimethicone conditions skin and acts as an emollient by laying down a thin flexible veil that locks in moisture, softens rough patches and gives creams a silky glide. Its smooth finish and water resistance explain why formulators reach for it in moisturizers, masks and primers, yet it remains a niche silicone rather than a household name.
Overall safety is high with very low irritation potential, no phototoxicity and a minimal likelihood of clogging pores. Still, skin can be unpredictable so it is wise to patch test any new product containing this ingredient before using it on the entire face.