Bis-Methoxy Peg-13 Peg-438/Ppg-110 Smdi Copolymer: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Bis-Methoxy Peg-13 Peg-438/Ppg-110 Smdi Copolymer?

Bis-Methoxy PEG-13 PEG-438/PPG-110 SMDI Copolymer is a lab-made ingredient created by linking two different kinds of water-loving polymers (polyethylene glycol and polypropylene glycol) with a small bridging molecule called saturated methylene diphenyldiisocyanate. The ends of the chain are capped with methoxy PEG-13, which helps keep the whole structure stable and easy to blend into water-based formulas. Because each part of the chain has a different weight and texture, chemists can fine-tune the final material to give a predictable, silky flow in creams and gels.

This type of copolymer came into cosmetic use in the late 1990s when brands wanted gentler options to control thickness without relying on heavy waxes or high amounts of salt. Its production is done in closed reactors where the PEG and PPG segments are reacted with SMDI under carefully controlled heat and pressure. After the chain is built to the right length, the ends are sealed with methoxy PEG-13, then the mixture is purified and dried into a pourable liquid or soft solid.

You will most often spot Bis-Methoxy PEG-13 PEG-438/PPG-110 SMDI Copolymer in lightweight moisturizers, anti-aging serums, sheet mask essences, hair conditioners and rinse-off cleansers that need to feel rich yet rinse clean.

Bis-Methoxy Peg-13 Peg-438/Ppg-110 Smdi Copolymer’s Cosmetic Benefits/Uses

This ingredient plays a single but important role in formulas.

As a viscosity controller it helps set the thickness of a product so it spreads evenly, stays stable on the shelf and gives a pleasing, non-greasy texture on the skin or hair. By fine-tuning flow it can prevent runny serums from dripping or heavy creams from feeling stiff, creating a smooth application experience every time.

Who Can Use Bis-Methoxy Peg-13 Peg-438/Ppg-110 Smdi Copolymer

Because it is a neutral viscosity controller with no active skin altering properties, this copolymer is generally suitable for all skin types including oily, combination, normal and dry skin. Sensitive or compromised skin usually tolerates it well since it does not penetrate deeply or change the skin’s pH, though anyone with a history of reacting to polyethylene glycol derivatives should proceed cautiously.

The material is synthesized entirely from petrochemical feedstocks so it contains no animal derived components, making it acceptable for both vegans and vegetarians.

No data suggest the ingredient poses specific risks during pregnancy or while breastfeeding when used topically in cosmetic amounts. This is not medical advice and people who are pregnant or nursing should still review any skincare routine with their healthcare provider to be safe.

Bis-Methoxy PEG-13 PEG-438/PPG-110 SMDI Copolymer does not make the skin more sensitive to sunlight and can be worn day or night without increasing the chance of sunburn.

Potential Side Effects/Adverse Reactions

Individual responses to topical Bis-Methoxy PEG-13 PEG-438/PPG-110 SMDI Copolymer vary. The points below outline potential side effects, though most users experience none when the ingredient is correctly formulated.

  • Mild transient redness or stinging in extremely sensitive skin
  • Contact allergy marked by itching or small rash in people allergic to PEG based ingredients
  • Eye irritation if a product accidentally gets into the eyes
  • Rare clogging or heaviness when used at high levels in leave-on formulas on very oily skin

If any irritation, rash or discomfort occurs discontinue use and seek medical advice if symptoms persist or worsen.

Comedogenic Rating

Bis-Methoxy PEG-13 PEG-438/PPG-110 SMDI Copolymer scores a 0-1 on the comedogenic scale. Its large water soluble polymer chains stay mainly on the skin’s surface and rinse away easily so they rarely block pores. Formulators also use it in low amounts aimed at adjusting texture rather than coating skin in a heavy film.

Given this low rating the ingredient is generally suitable for people who are prone to acne or frequent breakouts.

The finished product still matters. If the copolymer sits in a base loaded with rich oils or waxes the overall formula could feel occlusive even though the copolymer itself is lightweight.

Summary

Bis-Methoxy PEG-13 PEG-438/PPG-110 SMDI Copolymer acts chiefly as a viscosity controller that lets chemists fine-tune how runny or creamy a product feels. Its mixed PEG and PPG backbone pulls in water while the SMDI links add flexible strength so the formula glides on smoothly then leaves almost no residue.

You will spot it in a modest number of skin and hair products such as gel creams, light lotions and conditioners though it is not as common as staples like carbomer or xanthan gum.

Overall it has a strong safety profile with only occasional reports of irritation or allergy. Still, it is smart to do a quick patch test whenever you try a new product containing this copolymer to make sure it agrees with your skin.

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