Brassica Oleracea Italica Vesicles: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Brassica Oleracea Italica Vesicles?

Brassica Oleracea Italica Vesicles come from the broccoli plant, known botanically as Brassica oleracea italica. Scientists isolate tiny membrane-bound sacs, called vesicles, from the whole plant. These vesicles are naturally packed with sugars, amino acids, antioxidants and lipids that help the plant hold water and defend itself against stress. The idea of using plant vesicles in skin care emerged in the early 2010s when researchers noticed they could mimic some of the skin’s own protective structures. To obtain them, fresh broccoli is blended with water, filtered then put through a series of centrifugation steps that separate the vesicles without harsh solvents. The resulting concentrate is dried or kept in a buffered liquid so formulators can add it to creams, serums and sheet masks. Because of its water-binding and soothing profile it shows up most often in moisturizers, barrier-repair blends, after-sun lotions and anti-aging treatments.

Brassica Oleracea Italica Vesicles’s Cosmetic Benefits/Uses

This plant-derived ingredient offers two key actions that improve both product performance and skin feel.

  • Humectant – The vesicles draw moisture from the environment and hold it at the skin’s surface which helps keep the complexion soft, plump and comfortable
  • Skin Protecting – Their lipid shell forms a light, breathable shield that reduces transepidermal water loss and helps protect against daily irritants like pollution or harsh weather

Who Can Use Brassica Oleracea Italica Vesicles

The ingredient is generally well tolerated by all major skin types including dry, oily, combination and sensitive because its main job is to boost moisture while reinforcing the skin’s natural barrier. Very acne-prone users also tend to do well since the vesicles are lightweight and non greasy. There are no known reasons it would be unsuitable for any specific skin type.

Since the vesicles are sourced from broccoli and involve no animal derivatives or animal testing in their manufacture, formulas containing them are usually considered vegan and vegetarian friendly. Always check the finished product label for any additional non-plant ingredients.

Pregnant or breastfeeding individuals can usually apply products with Brassica Oleracea Italica Vesicles without special restrictions, however this is not medical advice. Anyone who is expecting or nursing should run the full ingredient list of any skin care product past a qualified health professional just to be safe.

The vesicles do not make skin more sensitive to sunlight so they do not increase the risk of sunburn. Standard daily sunscreen use is still recommended for overall skin health.

Potential Side Effects/Adverse Reactions

Reactions to topical Brassica Oleracea Italica Vesicles vary from person to person. The points below reflect potential side effects but most users have no issues when the ingredient is properly formulated and preserved.

  • Allergic response: itching rash or swelling in individuals with a known sensitivity to broccoli or other cruciferous vegetables
  • Irritation: mild stinging or redness on very reactive or compromised skin especially if the formula also contains strong acids or fragrances
  • Contact dermatitis: rare cases of eczematous irritation when the vesicles break down and release proteins a person is allergic to
  • Product spoilage related irritation: discomfort or breakouts if a poorly preserved formula allows microbial growth that the skin then reacts to

If you notice any of these effects discontinue use and seek guidance from a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 0–1 (very low)

Brassica Oleracea Italica Vesicles are mostly water based with only trace lipids, so they sit lightly on the skin and rinse away cleanly. They do not contain the heavy waxes or thick oils that normally block pores, which keeps the clogging risk close to zero. Because of this very low rating the ingredient is generally suitable for people who break out easily. If the finished product also includes rich butters, silicones or occlusive oils, pore-clogging potential will depend on those added materials, not on the vesicles themselves.

Summary

Brassica Oleracea Italica Vesicles act as a humectant by pulling water toward the skin and holding it there while their natural lipid shell adds a light barrier that helps cut water loss and shields against daily irritants. These two actions make formulas feel more hydrating and calming without added weight.

Though not yet a household name, the ingredient is gaining traction in moisturizers and soothing serums as brands look for gentle plant tech that improves skin feel. It is considered safe for all skin types, with very few reports of irritation or allergy. As with any new skincare product a quick patch test is still smart before full-face use.

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