Buteth-2 Acetate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Buteth-2 Acetate?

Buteth-2 Acetate is the acetate ester of diethylene glycol monobutyl ether, a clear liquid produced by reacting diethylene glycol, butanol and acetic acid. Because it is fully man-made, supply is stable and free from seasonal or geographic limits. The ingredient appeared in industrial cleaners in the 1950s thanks to its gentle solvency and low odor, then formulators noticed it worked well in personal care where strong solvents would irritate skin. Today manufacturers create it by acetylating 2-(2-butoxyethoxy)ethanol with acetic anhydride under controlled heat, followed by purification to cosmetic grade standards.

You will most often spot Buteth-2 Acetate in lightweight leave-on products that need to spread easily without feeling greasy, such as facial mists, toners, hydrating serums, quick-dry hair sprays, fragrance mists, nail polish removers, micellar waters and some silicone-free primers.

Buteth-2 Acetate’s Cosmetic Benefits/Uses

Formulators like this ingredient because it pulls double duty inside a single bottle.

  • Fragrance/Perfuming – its faint sweet scent can soften harsh raw material odors or boost a perfume blend helping products smell more pleasant straight out of the package and after application
  • Solvent – dissolves oils, resins and fragrance molecules so actives stay evenly distributed which prevents separation, improves clarity and ensures each pump or swipe delivers the intended mix of ingredients
  • Viscosity controlling – thins down thick bases making creams spreadable and sprays mist smoothly which gives the final formula the light elegant feel consumers look for

Who Can Use Buteth-2 Acetate

Because it is a lightweight solvent that evaporates cleanly, Buteth-2 Acetate is generally well tolerated by normal, oily, combination and even most dry skin types. Its non-greasy slip can leave very dry skin wanting an extra occlusive layer afterward, while extremely sensitive or compromised skin should approach with caution since any solvent can heighten stinging if the barrier is already damaged.

The ingredient is fully synthetic and contains no animal-derived matter so it is considered suitable for both vegans and vegetarians. As always, shoppers concerned about animal testing laws should verify the brand’s cruelty-free status rather than the raw material itself.

No published data link topical Buteth-2 Acetate to problems in pregnancy or while breastfeeding. The amounts left on skin after normal cosmetic use are minimal and systemic absorption is expected to be low. This is not medical advice and pregnant or nursing individuals should show any product they plan to use to their healthcare provider to be on the safe side.

Buteth-2 Acetate does not cause photosensitivity so it will not make skin more prone to sunburn. Routine daytime sun protection is still recommended for overall skin health.

Potential Side Effects/Adverse Reactions

Reactions to topical Buteth-2 Acetate vary from person to person. The points below list potential side effects that could occur though most users should not expect to experience them when the ingredient is used correctly in a finished formula.

  • Mild transient stinging on cracked or freshly exfoliated skin
  • Temporary dryness or tightness if overused in leave-on products
  • Contact irritation or redness in individuals sensitive to glycol ethers
  • Eye watering or burning if the liquid or spray mist gets into the eyes
  • Headache or lightheadedness from inhaling concentrated vapors in poorly ventilated areas

If any discomfort, irritation or other unexpected reaction occurs discontinue use and seek advice from a medical professional.

Comedogenic Rating

Rating: 1 / 5

Buteth-2 Acetate is a light glycol ether that evaporates quickly and contains no heavy oils or waxes, so it is unlikely to block pores. It still earns a 1 instead of 0 because very high use levels could leave a slight residue that mixes with skin sebum, though this is rare in finished cosmetics.

People prone to acne or breakouts can generally use products containing this ingredient without added risk.

Its quick flash-off means it is most often paired with other low-clogging ingredients, further reducing pore-blocking potential.

Summary

Buteth-2 Acetate works as a subtle fragrance enhancer, an effective solvent that keeps formulas uniform and a viscosity controller that thins thick bases for a weightless feel. It does all of this while leaving minimal scent and zero greasy after-feel.

The ingredient pops up in niche categories like facial mists, lightweight serums and quick-dry hair sprays but it is not as widespread as classic alcohols or silicones, mainly because formulators reach for it when they want a gentle solvent with low odor.

Current data show it is low risk for skin irritation and non-sensitizing when used at cosmetic levels. As with any new product, do a quick patch test before full-face or full-body use to confirm personal compatibility.

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