C12-16 Pareth-6 Phosphate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is C12-16 Pareth-6 Phosphate?

C12-16 Pareth-6 Phosphate is a synthetic surfactant made by taking medium-chain fatty alcohols (with 12 to 16 carbon atoms) usually sourced from coconut or palm oil, adding an average of six ethylene oxide units to create a water-loving chain then attaching a phosphate group. This combination of oil-like and water-loving parts lets the ingredient mix oil and water with ease. The material entered mainstream personal care formulas in the late 1980s when brands looked for milder alternatives to traditional sulfates. Its production involves three main steps: purification of the natural fatty alcohols, controlled reaction with ethylene oxide to reach the target six-unit average then phosphoric acid treatment to give the final phosphate ester. You will commonly spot it in face cleansers, micellar waters, body washes, exfoliating scrubs, makeup removers, lightweight lotions, hair shampoos and scalp treatments where gentle yet effective cleansing is needed.

C12-16 Pareth-6 Phosphate’s Cosmetic Benefits/Uses

This multitasking ingredient brings several practical benefits to everyday beauty products:

  • Cleansing: Lowers surface tension so water can lift away dirt, excess oil and makeup without harsh rubbing which helps deliver a fresh comfortable feel after rinsing
  • Emulsifying: Keeps oil and water phases blended in stable creams and gels so the formula stays smooth distributes active ingredients evenly and has an appealing texture

Who Can Use C12-16 Pareth-6 Phosphate

This ingredient is generally well tolerated by most skin types including normal oily dry and combination skin. Its mildness compared with harsher sulfates makes it a good choice for sensitive skin too, though individuals with a known sensitivity to ethoxylated surfactants should proceed carefully. Because it is produced from plant-derived fatty alcohols and contains no animal by-products it is suitable for both vegans and vegetarians.

Current data does not raise specific concerns for pregnant or breastfeeding women when the ingredient is used in rinse-off or leave-on cosmetics at typical levels. Still this is not medical advice and anyone who is pregnant or nursing should review any skincare routine with a qualified healthcare professional to be certain.

C12-16 Pareth-6 Phosphate is not known to cause photosensitivity so it will not make skin more prone to sunburn. It is also odorless and free of common fragrance allergens which can be a plus for fragrance-sensitive users.

Potential Side Effects/Adverse Reactions

Reactions to topical C12-16 Pareth-6 Phosphate differ from person to person. The points below list potential issues only and most people will never experience them when the ingredient is used at the levels found in finished products.

  • Mild skin dryness
  • Temporary stinging or redness on very sensitive skin
  • Eye irritation if the product accidentally gets into the eyes
  • Contact dermatitis in individuals with an allergy to ethoxylated surfactants

If any irritation or discomfort develops stop using the product and consult a healthcare professional if symptoms persist or worsen.

Comedogenic Rating

Rating: 1 (very low likelihood of clogging pores)

C12-16 Pareth-6 Phosphate is highly water-soluble and typically used in rinse-off cleansers so it does not sit on skin long enough to block follicles. Its molecular structure is large and hydrophilic which further reduces the chance of forming comedones. Because of these factors it is generally suitable for people who are prone to acne or breakouts.

Formulas that pair this surfactant with heavy oils or waxes could still trigger congestion so the overall product makeup matters more than the single ingredient.

Summary

C12-16 Pareth-6 Phosphate works primarily as a gentle cleanser and emulsifier. The phosphate-ended ethoxylated chain lowers water’s surface tension so grime lifts away easily, while the balanced oil-loving and water-loving segments keep oil and water phases mixed for uniform, stable textures.

Although not as famous as sodium laureth sulfate or cocamidopropyl betaine it has carved out a niche in modern skincare and haircare as a milder alternative that still foams well.

Overall safety data show low irritation potential for most users at standard use levels. As with any cosmetic ingredient it is wise to patch test new products to rule out personal sensitivities and enjoy worry-free use.

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