Camellia Sinensis Callus Culture Lysate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
Share:
Inside this article:

All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Camellia Sinensis Callus Culture Lysate?

Camellia Sinensis Callus Culture Lysate comes from the tea plant Camellia sinensis, the same plant that gives us green, black and white tea. Scientists take a tiny piece of the plant, encourage it to grow as a mass of undifferentiated cells called a callus, then break those cells open to release their contents. The resulting lysate is rich in tea-derived polyphenols such as epigallocatechin gallate, along with amino acids, sugars and minerals that support skin health.

The beauty world has long leaned on tea extracts for their antioxidant punch. Advances in plant tissue culture during the early 2000s allowed labs to grow tea cells under controlled conditions, creating a sustainable supply free from pesticides and seasonal swings. By lysing the cultured cells, formulators gain access to concentrated active molecules that can be standardized for consistency batch after batch.

After the callus cells are grown in a sterile nutrient medium, they are harvested, gently disrupted with enzymes or ultrasound, then filtered to remove debris. The clear lysate can be blended into water-based phases, making it easy to insert into finished products without heavy processing.

You will spot Camellia Sinensis Callus Culture Lysate in antioxidant serums, anti-aging creams, calming masks, daily moisturizers and protective after-sun formulas where brands want the benefits of tea actives in a stable user-friendly form.

Camellia Sinensis Callus Culture Lysate’s Cosmetic Benefits/Uses

Below are the main roles this ingredient plays inside a formula and what each one means for your skin

  • Antioxidant: Helps neutralize free radicals generated by UV light and pollution which in turn supports a brighter more even-toned complexion and may slow the look of premature aging
  • Skin Conditioning: Supplies amino acids and sugars that help soften skin and improve its ability to hold water leaving it feeling smoother and more supple
  • Skin Protecting: Forms a gentle shield that reinforces the skin barrier reducing the impact of daily environmental stressors and supporting overall resilience

Who Can Use Camellia Sinensis Callus Culture Lysate

This tea-derived lysate is gentle enough for most skin types including dry, sensitive, combination and oily skin. Its soothing antioxidant profile brings extra value to easily irritated or redness-prone complexions without adding heaviness that might weigh on oily skin. There are no components in the ingredient itself that inherently clash with any specific skin type although, as with any botanical, extremely reactive skin could still find it stimulating.

The lysate is produced entirely from plant cells grown in a lab so it is suitable for both vegans and vegetarians. No animal-derived media or by-products are required for the culture process.

No data suggests a particular risk for pregnant or breastfeeding individuals when this ingredient is applied topically in cosmetic concentrations. Still this is not medical advice and anyone who is pregnant or nursing should have their doctor review their skincare routine before use.

Camellia Sinensis Callus Culture Lysate does not make skin more sensitive to sunlight so it can be used morning or night without increasing the need for SPF beyond regular daily protection.

Potential Side Effects/Adverse Reactions

Reactions to topical Camellia Sinensis Callus Culture Lysate differ from person to person. The points below outline potential side effects which remain uncommon when the ingredient is properly formulated and used as directed.

  • Mild redness or stinging
  • Itchiness or burning on very sensitive or compromised skin
  • Allergic contact dermatitis in individuals allergic to tea plant compounds
  • Cross-reactivity with other botanical allergens leading to localized rash

If any irritation or discomfort develops stop using the product and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 0/5

Camellia Sinensis Callus Culture Lysate is a water soluble extract with no oily or waxy residues that could clog pores. The molecules it delivers, chiefly tea polyphenols, amino acids and sugars, sit lightly on the skin and rinse away easily. Because it does not form an occlusive film or feed surface bacteria it earns a zero on the comedogenic scale.

In practical terms this means the lysate is considered safe for acne prone or breakout prone skin.

The only caveat is that overall formula design matters. If the product containing this lysate is packed with heavy oils or butters pore clogging can still occur though the lysate itself remains non-comedogenic.

Summary

Camellia Sinensis Callus Culture Lysate acts as an antioxidant, skin conditioner and skin protectant. The concentrated tea polyphenols mop up free radicals, helping to keep tone bright and signs of early aging at bay. Natural sugars and amino acids draw moisture and smooth texture while a gentle bio-film reinforces the barrier so skin can better fend off daily environmental stress.

The ingredient is gaining attention as brands look for sustainable plant actives that are both effective and consistent, though it is not yet as common as traditional green tea extracts.

Topical use is considered very safe with a low risk of irritation or pore clogging. As with any new skincare product, patch testing on a small area first is always a smart idea to be sure it suits your individual skin.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search