Ceteareth-16: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Ceteareth-16?

Ceteareth-16 is a synthetic compound created by reacting a blend of cetyl and stearyl fatty alcohols with about sixteen units of ethylene oxide. The starting fatty alcohols are commonly sourced from vegetable oils like coconut or palm, though they can also come from petroleum derivatives. The controlled addition of ethylene oxide turns these otherwise oily alcohols into a waxy, water-compatible ingredient that can mix oil and water phases with ease.

Interest in ethoxylated fatty alcohols grew in the mid-20th century when formulators looked for safer alternatives to harsh soaps. Ceteareth-16 quickly became popular for its balanced ability to clean skin while keeping textures smooth. Production involves heating the fatty alcohol blend, introducing ethylene oxide gas under pressure, then purifying the resulting material to remove residual reactants.

You will most often see Ceteareth-16 in rinse-off cleansers, facial masks, lightweight moisturizers, exfoliating scrubs, hair conditioners, styling creams and sun care products where a stable, creamy texture is desired.

Ceteareth-16’s Cosmetic Benefits/Uses

Formulators rely on Ceteareth-16 for a couple of key jobs that improve both product performance and the user experience

  • Cleansing: Its amphiphilic structure lets it surround dirt and excess oil so they can be rinsed away without stripping skin or hair, resulting in a gentle yet effective clean
  • Emulsifying: By lowering the surface tension between oil and water, it creates stable emulsions that stay smooth and homogenous, which means creams that do not separate and lotions that feel consistently silky

Who Can Use Ceteareth-16

Ceteareth-16 is generally well tolerated by most skin types, including normal, oily, combination and dry skin, because it cleanses without stripping natural oils and helps keep formulas lightweight. Very sensitive or severely compromised skin may find any surfactant, including Ceteareth-16, a bit irritating if used at high levels or left on for extended periods, so extra caution is advised for those groups.

The ingredient is usually suitable for vegans and vegetarians since the fatty alcohols in modern manufacturing are most often sourced from plant oils such as coconut or palm. If animal-derived feedstocks matter to you, check with the brand for confirmation.

No published data show that Ceteareth-16 poses specific risks to women who are pregnant or breastfeeding when used topically in cosmetics. Still, this is not medical advice and anyone who is pregnant or nursing should run any skincare product past a qualified healthcare professional to be on the safe side.

Ceteareth-16 does not induce photosensitivity and there are no known interactions with sun exposure, so it will not make skin more prone to sunburn. It is also odorless and nonvolatile, making it friendly for users sensitive to strong scents.

Potential Side Effects/Adverse Reactions

Reactions to Ceteareth-16 can vary from person to person. The points below list potential side effects but they are uncommon when the ingredient is used correctly by reputable manufacturers.

  • Mild skin irritation such as redness stinging or itching, especially on sensitive or broken skin
  • Allergic contact dermatitis in individuals with a specific sensitivity to ethoxylated fatty alcohols
  • Eye irritation if a product containing Ceteareth-16 accidentally gets into the eyes
  • Barrier disruption or dryness if used in very high concentrations or in multiple products layered together
  • Trace residues of 1,4-dioxane from inadequate purification, though reputable brands remove these to below safety thresholds

If you notice any of these reactions stop using the product and consult a healthcare professional

Comedogenic Rating

Rating: 2/5 (low)

Ceteareth-16 is derived from fatty alcohols, yet the ethoxylation process makes it more water compatible and less likely to clog pores than straight oils or waxes. Most formulators use it at modest levels simply to stabilize emulsions, further reducing any pore-blocking risk. That said, it still has a mild lipid backbone so very oily or congestion-prone skin could notice a small increase in blackheads if the rest of the formula is rich or occlusive.

Overall it is generally fine for acne-prone users when used in lightweight cleansers or lotions, but those extremely sensitive to buildup may prefer ingredients rated 0 or 1.

Comedogenicity can be influenced by the entire formula, application frequency and individual skin chemistry, so the same product may behave differently from person to person.

Summary

Ceteareth-16 mainly acts as a gentle cleanser and a reliable emulsifier. Its amphiphilic structure latches onto oil and water at the same time, letting it lift grime from skin or hair while holding emulsions together so creams stay smooth and lotions stay fluid.

It remains a staple in many mainstream cleansers, masks, conditioners and sunscreens because it is cost-effective, versatile and easy to formulate with. You will not see the ingredient headlining trendy marketing campaigns, yet behind the scenes it quietly does the heavy lifting in countless everyday products.

When produced and purified correctly Ceteareth-16 is considered safe for topical use by the cosmetic industry and regulatory bodies worldwide. Still, everyone’s skin is unique, so it is wise to patch test any new product containing this or any other surfactant before committing it to full-face use.

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