Cetoleth-15: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Cetoleth-15?

Cetoleth-15 is a synthetic ingredient made by attaching about fifteen units of ethylene oxide to fatty alcohols that come mainly from cetyl and oleyl sources. These fatty alcohols are usually derived from plant oils or sustainably sourced animal fats, giving the final material a partly natural backbone with added lab-made parts that improve its performance. Cosmetic chemists began using ethoxylated fatty alcohols in the late 1960s when they were looking for gentler yet effective surface-active agents. Over time Cetoleth-15 earned a place in many formulas because it mixes oil and water smoothly and helps rinse dirt away without stripping skin.

The manufacturing process starts with purified cetyl and oleyl alcohols that react with ethylene oxide gas under controlled heat and pressure. The reaction is carefully timed to hit an average of fifteen ethylene oxide units per molecule. After neutralization and filtration the result is a waxy to pasty solid that melts into liquids during production.

Formulators reach for Cetoleth-15 in products where a light, non-heavy feel is important. You will often see it in facial cleansers, micellar waters, daily moisturizers, wash-off masks, body lotions, light conditioners and anti-aging serums that need to keep water and oil phases stable.

Cetoleth-15’s Cosmetic Benefits/Uses

In skin and hair products Cetoleth-15 pulls double duty that improves both texture and performance

  • Cleansing: Its surface-active nature loosens makeup, sebum and grime so they can be rinsed away with water. Because it is milder than many sulfate-based surfactants it helps cleansers feel gentle and leave skin soft
  • Emulsifying: The ingredient acts as a bridge between oil and water phases, creating stable emulsions that resist separating on the shelf or on the skin. This lets formulators craft lightweight lotions and creams that spread evenly, absorb well and deliver active ingredients more consistently

Who Can Use Cetoleth-15

Cetoleth-15 is generally suitable for most skin types including dry, normal, combination and oily because it cleanses without harsh stripping and leaves little residue. People with very sensitive or compromised skin may still want to monitor how their skin feels, as any surfactant can occasionally cause tightness in those conditions.

The ingredient itself is vegan friendly when the base fatty alcohols are sourced from plants, which is common in modern supply chains. Some batches can come from sustainably harvested animal fats, so strict vegans or vegetarians should look for brands that specify vegetable origin or carry a certified vegan logo.

Cetoleth-15 has no known hormonal activity and is not readily absorbed through intact skin, so it is generally considered safe for use during pregnancy or while breastfeeding. This is not medical advice and anyone who is pregnant or nursing should always run their skincare routine past a doctor to be sure.

The molecule does not make skin more sensitive to sunlight and has no documented phototoxic effects. It is also compatible with most other common skincare ingredients, so formulators can include it without special restrictions.

Potential Side Effects/Adverse Reactions

Individual responses to topical Cetoleth-15 can vary. The effects listed below are potential outcomes, not the typical user experience. When properly formulated most users will notice no negative effects.

  • Transient skin irritation mild redness stinging or itching can occur in very sensitive individuals or if the formula contains a high concentration of Cetoleth-15
  • Allergic contact dermatitis rare cases of true allergy have been reported with ethoxylated alcohols leading to persistent rash or swelling
  • Eye irritation accidental contact may cause watery eyes or a brief burning sensation especially in cleansers that are rinsed too slowly
  • Dryness or tightness overuse of products rich in surfactants can disrupt the skin barrier making it feel dry or rough

If you experience any of the above stop using the product and seek advice from a qualified healthcare provider or dermatologist.

Comedogenic Rating

Rating: 1/5. Cetoleth-15 is an ethoxylated fatty alcohol, so the water-loving ethoxy groups keep it from lodging in pores the way raw cetyl or oleyl alcohol sometimes can. It usually sits on the skin only briefly in cleansers or is used at low levels in lotions, which further lowers any clogging risk.

Because of this low score it is generally considered suitable for people who are prone to acne or breakouts.

As with any ingredient, very heavy formulas or high percentages could tip the balance for some users, yet that is uncommon given how formulators dose this material.

Summary

Cetoleth-15 works mainly as a mild cleanser and an emulsifier. Its surfactant side breaks up oil and dirt so they rinse away easily while its oil-friendly tail grabs onto the oily phase of a lotion and its water-friendly head holds on to the watery phase, keeping the mix smooth and stable.

It is a solid mid-tier helper that shows up in many mainstream face washes, light creams and micellar waters, though it is not a headline ingredient that brands advertise heavily.

Performance and safety data show a low irritation profile, no hormone action and a very small risk of pore clogging. Most people tolerate it well, yet everyone’s skin is different so it is smart to patch test any new product that contains Cetoleth-15.

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