Cetyl Hexacosyl Dimethicone: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Cetyl Hexacosyl Dimethicone?

Cetyl Hexacosyl Dimethicone is a silicone-based compound created by bonding long-chain fatty alcohols, most notably cetyl and hexacosyl groups, to a dimethicone backbone. The result is a hybrid molecule that combines the silky glide of dimethicone with the rich, cushiony feel of natural waxy alcohols. It originated in the late 1990s when formulators searched for silicones that could mimic the comforting texture of plant oils without the greasiness. The ingredient is made through a controlled reaction where the fatty alcohols are chemically attached to dimethicone in a clean, solvent-free process, then purified into a soft, semi-solid material.

You will spot Cetyl Hexacosyl Dimethicone in moisturizers, night creams, anti-aging serums, conditioning hair masks, lightweight facial oils, primers, and occasional lip balms. Brands favor it for the smooth, non-sticky finish it lends to formulas, making products feel luxurious while helping them spread evenly across skin or hair.

Cetyl Hexacosyl Dimethicone’s Cosmetic Benefits/Uses

Cetyl Hexacosyl Dimethicone mainly acts as an emollient, giving products a plush feel while supporting skin softness. By filling in microscopic gaps on the skin surface it leaves a smooth, supple finish and helps lock in moisture without a heavy oily residue. Its silicone backbone adds slip, which lets creams glide on effortlessly and improves overall sensorial appeal.

Who Can Use Cetyl Hexacosyl Dimethicone

Cetyl Hexacosyl Dimethicone is gentle enough for most skin types. Dry and mature complexions often benefit the most because the ingredient softens rough spots and seals in moisture, while normal and combination skin enjoy its light silky feel that does not leave a greasy film. Oily or very acne-prone skin can usually tolerate it too since it is less occlusive than many plant oils, yet those who break out easily might prefer to patch-test first because any rich emollient has the potential to trap debris in pores.

The ingredient is produced synthetically from fatty alcohols that are typically sourced from coconut or palm and then bonded to a silicone base, so there is no animal input. This makes it suitable for vegans and vegetarians looking to avoid animal-derived additives.

No data suggest that Cetyl Hexacosyl Dimethicone poses a risk during pregnancy or while breastfeeding. Topical silicones are considered inert and absorb minimally, but this is not medical advice and anyone who is pregnant or nursing should run any skincare product past their doctor to be on the safe side.

Cetyl Hexacosyl Dimethicone does not increase photosensitivity, so there is no special sun-related caution beyond standard daily sunscreen use. It also plays nicely with most active ingredients and has no known incompatibilities worth highlighting.

Potential Side Effects/Adverse Reactions

Side effects and reactions to topical Cetyl Hexacosyl Dimethicone can vary from person to person. The following points outline potential issues that could occur, yet they are unlikely to reflect the average user experience when the ingredient is used correctly in a well-formulated product.

Contact irritation – A small percentage of users with highly reactive skin may notice redness, itching or a mild burning sensation

Clogged pores or comedones – Although uncommon, very acne-prone individuals might experience congestion if the formula is heavy or layered with several occlusive products

Product buildup on hair – In rinse-off conditioners and masks the silicone component can accumulate over time making strands look limp or dull if not clarified periodically

Eye discomfort – If a facial product migrates into the eyes it can cause temporary blurriness or stinging because of the silicone film

If any adverse reaction occurs stop using the product and seek advice from a qualified healthcare professional.

Comedogenic Rating

Rating: 1/5 Cetyl Hexacosyl Dimethicone sits low on the comedogenic scale because its silicone backbone forms a breathable film that is less likely to block pores than heavier plant oils or waxes. The attached fatty alcohol chains boost softness yet stay chemically bound, so they do not separate out and settle in follicles.

Most people prone to acne or breakouts can use products containing this ingredient without major concern.

Overall pore-clogging potential depends on the finished formula: a light gel cream with a small dose of this silicone will behave very differently from a dense balm packed with multiple occlusive agents.

Summary

Cetyl Hexacosyl Dimethicone acts mainly as an emollient, gliding over the skin surface to fill tiny gaps, soften rough spots and slow moisture loss. Its silicone side brings slip while the long chain fatty alcohols add plush body so creams spread effortlessly and leave a refined, non-greasy finish.

The ingredient shows up in a fair number of moisturizers, primers and hair masks yet it is not as widespread as basic dimethicone or common plant oils. Brands looking for a luxe feel without extra shine often reach for it.

Decades of topical use plus available safety data point to a low irritation risk and negligible absorption. Even so it is always smart to patch test any new product to confirm personal tolerance before full-face or daily use.

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