Cetyl Myristoleate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Cetyl Myristoleate?

Cetyl Myristoleate is an ester formed when cetyl alcohol, a fatty alcohol usually derived from coconut or palm oil, reacts with myristoleic acid, a monounsaturated fatty acid most often sourced from plant oils such as avocado or macadamia. First noted in the 1990s for its lubricating qualities in wellness circles, it soon caught the attention of cosmetic chemists looking for skin friendly emollients that blended well with other ingredients and left a smooth non-greasy finish. Today it is produced through a controlled esterification process where purified cetyl alcohol and myristoleic acid are combined under heat with a catalyst then filtered and refined to yield a waxy solid or flakes. Because of its silk-like feel and stability, Cetyl Myristoleate shows up in moisturizers, facial masks, anti-aging creams, body lotions, hand balms and targeted treatment products that aim to soften dry or mature skin.

Cetyl Myristoleate’s Cosmetic Benefits/Uses

In topical formulas Cetyl Myristoleate serves a single key role: skin conditioning. By forming a light breathable layer on the surface it helps trap moisture, smooth rough patches and enhance the overall feel of a product. This improves spreadability so creams glide on easily and gives skin a soft supple finish without a heavy residue.

Who Can Use Cetyl Myristoleate

Cetyl Myristoleate is generally suitable for normal, dry, combination and mature skin thanks to its light occlusive properties that lock in moisture without a greasy feel. Those with very oily or easily congested skin may find it a bit too rich and could prefer lighter emollients instead.

The ingredient is synthesized from cetyl alcohol and myristoleic acid that are usually sourced from plant oils, so most cosmetic-grade material is vegan friendly. If a strictly vegan or vegetarian routine is important, look for brands that clearly confirm a plant origin because older manufacturing methods sometimes relied on animal fats.

No specific warnings exist for pregnant or breastfeeding women, and Cetyl Myristoleate is not known to penetrate deeply or act hormonally. Even so this is not medical advice and expectant or nursing mothers should have any skincare product they plan to use reviewed by their doctor just to be safe.

Cetyl Myristoleate does not increase photosensitivity, so there is no extra need for sun avoidance beyond standard daily SPF practice.

Potential Side Effects/Adverse Reactions

Responses to topical Cetyl Myristoleate differ from person to person. The following are potential side effects that have been reported, but most users tolerate the ingredient well when it is properly formulated in a product.

  • Mild redness or stinging in very sensitive skin
  • Itching or localized irritation for people allergic to fatty alcohols or esters
  • Allergic contact dermatitis presenting as small bumps or rash
  • Temporary clogged pores or breakouts in individuals prone to acne
  • Rare cases of hives or swelling if a true allergy exists

If any of these reactions occur stop using the product and seek guidance from a healthcare professional.

Comedogenic Rating

Rating: 2/5

Cetyl Myristoleate is a mid-weight fatty ester that sits on the skin to reduce moisture loss. Its molecular size is smaller than heavier plant butters yet larger than light silicones, so it has a mild tendency to nestle into pores if used in very rich concentrations or layered under occlusive products. Most formulations use it at levels low enough to stay comfortable on normal and dry skin without causing widespread congestion.

Suitable for acne-prone skin: generally yes in low to moderate amounts, but very oily or highly clog-prone users may prefer lighter alternatives.

Products that pair Cetyl Myristoleate with non-film-forming humectants or oil-absorbing powders usually minimize any pore-clogging risk.

Summary

Cetyl Myristoleate conditions skin by forming a thin breathable film that slows water loss, smooths rough patches and gives creams a silkier glide. Its popularity is modest; formulators reach for it when they want a plant-derived emollient that feels richer than cyclomethicone yet less greasy than pure oils.

Safety records show a low rate of irritation or allergy and no evidence of systemic effects, making it a largely safe addition to skincare. As with any new ingredient it is smart to patch test first to make sure your skin agrees with it.

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