Cetyl Phosphate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Cetyl Phosphate?

Cetyl Phosphate is the cosmetic name for hexadecyl dihydrogen phosphate, a compound made by reacting cetyl alcohol with phosphoric acid. Cetyl alcohol is a fatty alcohol that can be sourced from coconut or palm oil, so the final ingredient often starts with renewable plant material though it is finished in a lab for purity and consistency. Chemists introduced Cetyl Phosphate to skin care in the late 1970s when they were looking for gentle surfactants that could also stabilize oil and water mixes. Production involves heating the fatty alcohol with phosphoric acid, then neutralizing and purifying the result to create a fine powder or viscous liquid that disperses easily in water.

Formulators like Cetyl Phosphate because it does two jobs at once, so it shows up in many product types: facial cleansers, make up removers, lightweight lotions, richer creams, sunscreens, masks and even tinted moisturizers. Its dual action lets brands simplify ingredient lists without giving up performance.

Cetyl Phosphate’s Cosmetic Benefits/Uses

This multitasker improves both how a product feels and how well it works

  • Cleansing: The ingredient lowers surface tension so water can mix with oil and dirt lifting them away from skin. It creates a mild foam and leaves a fresh finish which is why it appears in face washes and micellar waters.
  • Emulsifying: Cetyl Phosphate keeps oils and waters blended, preventing separation during storage and use. This stability helps creams stay silky, stops sunscreens from clumping and gives lotions a smooth glide.

Who Can Use Cetyl Phosphate

Cetyl Phosphate is gentle enough for most skin types. Its mild cleansing action and low likelihood of clogging pores make it a good fit for oily, combination, normal and even sensitive skin. Dry skin can also benefit because it helps formulas hold moisture in place. People with very reactive or highly compromised skin should introduce any new product slowly, as they would with any ingredient, to make sure it does not trigger redness or stinging.

The ingredient is usually produced from plant derived cetyl alcohol so it is suitable for vegans and vegetarians. Brands that source cetyl alcohol from palm or coconut often state this on the label for added peace of mind.

No data shows that Cetyl Phosphate poses a special risk to pregnant or breastfeeding women when used topically. This is not medical advice and anyone who is pregnant or nursing should still discuss any skincare routine with a physician to be safe.

Cetyl Phosphate does not make skin more sensitive to sunlight so it will not increase the risk of sunburn. It also plays well with most other common skincare ingredients and does not interfere with actives like vitamin C, niacinamide or retinoids.

Potential Side Effects/Adverse Reactions

Reactions to Cetyl Phosphate are rare but every skin is different. The following points list potential side effects that could occur, though most people will not experience them when the ingredient is used correctly in a finished product.

  • Mild skin irritation Some users with very sensitive skin may notice temporary redness or a tingling sensation
  • Contact dermatitis In extremely uncommon cases an allergic response could appear with itching or small bumps
  • Eye irritation If a cleanser containing Cetyl Phosphate gets into the eyes it may cause brief stinging or watering

If you experience any of the above stop using the product and consult a healthcare professional.

Comedogenic Rating

Rating: 2 out of 5

Cetyl Phosphate is made from a fatty alcohol but its phosphate group helps it rinse or rub off the skin more easily than straight oils. It is normally used at low levels, often in rinse-off cleansers or light emulsions, so it has a low to moderate chance of clogging pores. Most acne-prone users tolerate it well, though those with very reactive or severely congested skin might still prefer true non-comedogenic options. Formulation matters too: paired with heavy oils the overall product could still be pore-clogging.

Summary

Cetyl Phosphate works as a mild cleanser and as an emulsifier that keeps oil and water mixed. It lowers surface tension so dirt lifts away then locks formulas into a smooth uniform texture, which is why it shows up in face washes, lotions, sunscreens and makeup removers.

The ingredient is fairly popular with formulators because it lets them cut down on extra surfactants and stabilizers while keeping products lightweight. It is less famous with shoppers but you will spot it on many ingredient lists once you start looking.

Overall safety data look good: irritation and allergy are rare and it has a low comedogenic rating. As with any new skincare product it is smart to patch test first so you can be sure your skin gets along with the full formula.

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