Cetyldimethylsiloxy Trimethylsiloxysilicate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Cetyldimethylsiloxy Trimethylsiloxysilicate?

Cetyldimethylsiloxy Trimethylsiloxysilicate is a specialty silicone resin formed when tetramethyldicetyldisiloxane, chlorotrimethylsilane and tetraethylorthosilicate are mixed with water under carefully controlled conditions. The water breaks their bonds in a process called hydrolysis, then the fragments link together again through condensation to create a stable network of silicon oxygen chains decorated with cetyl and trimethyl groups. The end result is a clear flexible resin that is usually supplied as a powder or dispersed in volatile silicone fluid.

Silicones started appearing in cosmetics in the 1950s because they glide easily on skin and resist water. Chemists kept tweaking their structures to get better wear times, softer feel and stronger films. Cetyldimethylsiloxy Trimethylsiloxysilicate is one of those later tweaks, first showing up in long wear makeup and high performance sunscreens in the early 2000s.

Manufacturers produce it in closed reactors so moisture levels, temperature and pH stay within tight limits. After reaction they strip off alcohol and hydrochloric acid byproducts, filter out any solids then standardize the viscosity. The purified resin ends up in drums ready for cosmetic labs.

You will most often find this ingredient in long wear liquid foundations, transfer resistant lipsticks, waterproof mascaras, facial primers, sunscreen creams, skin protectant ointments and occasionally in sheet mask essences for an extra occlusive boost.

Cetyldimethylsiloxy Trimethylsiloxysilicate’s Cosmetic Benefits/Uses

In cosmetic formulas Cetyldimethylsiloxy Trimethylsiloxysilicate serves as a skin protecting agent. When spread on the face it forms a thin breathable film that locks in moisture and shields skin from wind, pollutants and sweat. The film helps pigments and UV filters stick to the skin so makeup lasts longer and sunscreens stay effective after swimming or exercise. At the same time the silicone structure gives products a silky slip without feeling greasy which improves overall application comfort.

Who Can Use Cetyldimethylsiloxy Trimethylsiloxysilicate

This silicone resin suits most skin types including dry, normal and combination skin because it forms a light film that keeps moisture from escaping without feeling heavy. Oily or acne-prone skin can also use it since the ingredient itself is non-greasy and lets skin breathe, though very oil-rich formulas that contain it might still feel too occlusive for some. Sensitive skin generally tolerates it well because it is chemically inert and fragrance free.

Cetyldimethylsiloxy Trimethylsiloxysilicate is a lab-made compound with no animal-derived parts so products that rely on it are usually fine for vegans and vegetarians. Always check the full ingredient list to make sure the rest of the formula meets personal ethics.

Current safety data show no special risks for pregnant or breastfeeding women when the ingredient is used on the skin. That said this is not medical advice and anyone who is expecting or nursing should have a doctor review all skin or makeup products just to be safe.

The ingredient does not increase sensitivity to sunlight and will not lower the protection of a sunscreen. In fact it often boosts water resistance so SPF products stay on the skin longer.

Potential Side Effects/Adverse Reactions

Reactions to topical Cetyldimethylsiloxy Trimethylsiloxysilicate differ from person to person. The points below outline potential issues though they are uncommon when the ingredient is used in a well-made product.

  • Mild skin irritation
  • Redness or itching in people with a silicone allergy
  • Eye stinging if a product containing the resin gets into the eye
  • Temporary clogged pores if layered with very rich creams

If any irritation or other unwanted effect appears stop using the product and consult a healthcare professional.

Comedogenic Rating

Rating: 1 / 5. Cetyldimethylsiloxy Trimethylsiloxysilicate is a large inert silicone resin that sits on top of the skin rather than seeping into pores, so it is unlikely to trap oil and bacteria the way heavier plant oils or waxes can. It forms a flexible breathable film that water can still pass through which further reduces the chance of pore blockage. For most acne-prone users this ingredient is considered low risk.

Its comedogenic impact depends on the full formula. Products that pair the resin with rich butters or heavy mineral oils may feel more occlusive than the resin alone so the overall breakout risk will rise with those added components.

Summary

Cetyldimethylsiloxy Trimethylsiloxysilicate acts mainly as a skin protectant and film former. Once applied it creates a thin even layer that locks in moisture shields skin from sweat and pollution and anchors pigments or UV filters so makeup and sunscreen last longer. The silicone backbone gives a silky glide making products feel smoother during application.

While not a household name it is a quiet workhorse in long wear foundations waterproof mascaras and high-performance sunscreens where durability matters more than a flashy label.

Current research and decades of cosmetic use show it to be safe non-sensitizing and generally well tolerated by all skin types. As with any new product though it is wise to patch test first so you can catch any individual sensitivity before applying it over larger areas.

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