Chitosan Glycolate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Chitosan Glycolate?

Chitosan glycolate is a water-friendly form of chitosan, a substance obtained from chitin, the fibrous material that makes up the shells of shrimp, crab and other crustaceans. By reacting chitosan with glycolic acid scientists create chitosan hydroxyacetate, a salt that dissolves easily in water and stays stable in a wide range of skin-care formulas.

Chitosan itself has been studied since the 1960s for medical dressings because it can form breathable films that protect skin. In the 1990s cosmetic chemists began exploring its gentler salts, including chitosan glycolate, to bring the same protective qualities to beauty products without a sticky feel.

Manufacturing starts with cleaned shell powder. The shells are treated with alkali to remove proteins then with acid to strip out minerals. The resulting chitin is de-acetylated to make chitosan. Finally glycolic acid is added, turning it into chitosan glycolate, which is filtered and dried into a fine powder.

Because it is water soluble and has a soft, non-tacky finish, chitosan glycolate appears in sheet masks, serums, anti-aging creams, after-sun gels and lightweight moisturizers. It also shows up in hair sprays and conditioners where a flexible film is needed.

Chitosan Glycolate’s Cosmetic Benefits/Uses

This ingredient pulls double duty in many formulas thanks to its varied properties

  • Antioxidant: Helps neutralize everyday free radicals produced by UV light and pollution so skin looks fresher and less dull
  • Film forming: Creates a thin breathable layer on skin or hair that locks in moisture, boosts smoothness and gives a soft touch finish without feeling heavy
  • Skin conditioning: Binds water to the surface and leaves a silky feel helping rough or dehydrated areas feel smoother and more comfortable

Who Can Use Chitosan Glycolate

Because it is lightweight and water soluble chitosan glycolate suits most skin types including oily, combination, dry and even sensitive skin that dislikes heavy occlusive films. Its breathable coating helps hold moisture without trapping excess oil so it can be a good pick for breakout-prone complexions as well. The main group that should pause are people with known shellfish allergies since the raw material comes from shrimp or crab shells and trace proteins can linger even after purification.

Chitosan glycolate is not considered vegan or vegetarian friendly because it is sourced from animal shells. While some laboratories make fungal-derived chitosan, the glycolate form sold for cosmetics is typically marine in origin so anyone avoiding animal products will want to skip it.

No studies have flagged problems for pregnant or breastfeeding women when using chitosan glycolate topically, but this is not medical advice. Expectant or nursing mothers should run any skincare product past their doctor to be safe.

The ingredient does not cause photosensitivity and will not make skin more vulnerable to sunburn. Standard daytime sun protection is still recommended, but extra precautions are unnecessary.

Potential Side Effects/Adverse Reactions

Responses to topical chitosan glycolate differ from person to person. The effects listed below are possible yet unlikely for most users when the ingredient is included at normal cosmetic levels.

  • Contact allergy in individuals sensitive to shellfish
  • Mild redness or itching on very reactive skin
  • Temporary tight or dry feel if used in a high-film formula without added humectants
  • Eye irritation if the product accidentally gets into the eyes

If any discomfort, swelling or persistent irritation develops stop using the product and consult a healthcare professional.

Comedogenic Rating

Rating: 1/5

Chitosan glycolate dissolves in water and forms an airy moisture-holding film rather than a heavy waxy layer, so it rarely blocks pores. It is normally used at just one or two percent of a formula which further limits any build-up.

Most people with acne or breakout-prone skin can use products containing this ingredient without added risk.

If a formula pairs it with thick oils or butters that already sit on the skin the overall product could still feel occlusive, but that would be due to the companions not the chitosan glycolate itself.

Summary

Chitosan glycolate acts as an antioxidant, a film former and a skin-conditioning agent. Its positive charge attracts it to the skin surface where it binds water, creates a flexible veil that slows moisture loss and helps neutralize everyday free radicals produced by sunlight and pollution.

Although chitosan has been studied for decades the glycolate salt remains a bit of a niche player in beauty lines, turning up mostly in Korean sheet masks, light gels and a handful of leave-in hair products rather than on every drugstore shelf.

Topical safety data show a very low rate of irritation with the main caveat being potential issues for people allergic to shellfish. For everyone else it is considered gentle, yet as with any new skincare ingredient it is wise to do a small patch test before adding it to a routine.

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