Copper Aminoacetylamino Imidazolyl Propanoate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Copper Aminoacetylamino Imidazolyl Propanoate?

Copper Aminoacetylamino Imidazolyl Propanoate is a lab made copper peptide, meaning a small protein fragment that has a copper ion attached to it. The peptide part helps guide copper, an essential trace mineral, into the upper layers of the skin where it can be put to work. Scientists began looking at copper peptides in the late 1970s for their potential to support wound healing; from there, formulators noticed the same properties could give skin care products an edge and the ingredient started appearing in cosmetics in the early 2000s.

The ingredient is created through a controlled reaction that bonds copper with a custom built peptide made from amino acids like glycine, alanine and histidine derivatives. Once the bonding is complete, the compound is purified, dried and milled into a fine blue green powder that dissolves easily in water based formulas.

You will most often spot Copper Aminoacetylamino Imidazolyl Propanoate in leave on products where it gets enough contact time to be effective. Common formats include anti aging serums, hydrating lotions, sheet masks and overnight treatments that promise smoother, firmer looking skin.

Copper Aminoacetylamino Imidazolyl Propanoate’s Cosmetic Benefits/Uses

This ingredient is valued for one main function in skin care formulas.

As a skin conditioning agent, Copper Aminoacetylamino Imidazolyl Propanoate helps improve the overall feel and appearance of skin. It supports a smoother surface, promotes a healthy looking tone and can leave skin feeling soft and supple after use.

Who Can Use Copper Aminoacetylamino Imidazolyl Propanoate

This peptide is gentle enough for most skin types, including dry, normal, combination and oily. Because it is lightweight and water soluble, it will not leave a greasy film which makes it comfortable even for acne-prone or sensitive complexions. Those with highly reactive skin or a known copper allergy should approach with caution as the mineral component could trigger irritation.

Copper Aminoacetylamino Imidazolyl Propanoate is synthesized entirely in a lab without animal-derived inputs so it is suitable for both vegans and vegetarians.

Current research does not link topical copper peptides to pregnancy or breastfeeding risks, but data is limited. This information is not medical advice and anyone who is pregnant or nursing should check with a doctor before adding new products to a routine.

The ingredient does not increase photosensitivity, so daytime application is safe when paired with regular sun protection. It also plays nicely with most other common skincare actives, although pairing it with very low pH acids could reduce its stability.

Potential Side Effects/Adverse Reactions

Individual responses to Copper Aminoacetylamino Imidazolyl Propanoate can differ. The points below outline potential side effects that could occur, but most users will not experience them when the ingredient is formulated and used correctly.

  • Mild redness or warmth shortly after application
  • Temporary tingling or stinging on very sensitive skin
  • Rare allergic contact dermatitis in those sensitive to copper
  • Discoloration of light fabrics if the product transfers before fully drying

If any discomfort or unusual reaction develops, discontinue use and seek guidance from a healthcare professional.

Comedogenic Rating

Rating: 0. Copper Aminoacetylamino Imidazolyl Propanoate is a small, water-soluble peptide that leaves no oily residue and does not clog pores. It lacks the heavy lipids and waxes that typically spark breakouts which keeps its pore-blocking potential at virtually zero. This makes it suitable for skin that is prone to acne or congestion. Because the peptide is often used at low concentrations and is quickly absorbed, it poses minimal risk of building up inside follicles. If the finished formula includes other richer ingredients, their presence rather than the copper peptide will determine the overall comedogenicity.

Summary

Copper Aminoacetylamino Imidazolyl Propanoate is mainly a skin-conditioning agent that helps skin feel smoother, look healthier and stay comfortably hydrated. The attached copper ion supports surface renewal while the peptide guides it into the skin for better efficacy. Although not as common as vitamin C or retinol, it has a loyal following in targeted serums and masks where users appreciate its lightweight texture and supportive benefits.

Current data places the ingredient in the low-risk category for topical use with only rare reports of irritation or allergy. As with any new skincare addition it is wise to perform a quick patch test to confirm personal tolerance before full-face application.

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