Cyclodextrin Crosspolymer: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 24, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Cyclodextrin Crosspolymer?

Cyclodextrin Crosspolymer is a network of ring-shaped sugar molecules called cyclodextrins that have been linked together with a gentle photo-initiated process. The result is a stable three-dimensional structure that is water loving yet able to grab onto oils and active ingredients. Originally studied in the 1990s for its ability to trap odors and flavors, the polymer soon drew the attention of skincare chemists looking for a safe way to form thin breathable films on the skin. Manufacture starts with plant-derived starch that is converted into cyclodextrin rings, then reacted with 2-acryloyloxyethylisocyanate. A light-activated catalyst, 2-hydroxy-4′-hydroxyethoxy-2-methylpropiophenone, triggers the rings to link together into a solid but flexible mesh. You will spot Cyclodextrin Crosspolymer in sheet masks, leave-on gels, anti-aging serums, soothing lotions and makeup primers where it boosts texture and wear.

Cyclodextrin Crosspolymer’s Cosmetic Benefits/Uses

In formulas Cyclodextrin Crosspolymer performs several helpful jobs that improve how a product feels and works on the skin:

  • Film Forming – dries to a weightless veil that locks in moisture keeps actives in place and adds a soft finish
  • Skin Protecting – creates a breathable shield that defends against daily grime and helps reduce irritation from external stress
  • Viscosity Controlling – thickens water-based systems without a heavy feel allowing lotions and serums to glide on smoothly

Who Can Use Cyclodextrin Crosspolymer

This ingredient is generally well tolerated by all skin types, including sensitive and acne prone skin, because it forms a breathable lightweight film rather than a heavy occlusive layer. Very dry skin may still need a richer moisturizer on top, but the polymer itself poses no special concerns.

Cyclodextrin Crosspolymer is produced from plant starch and synthetic linkers, with no animal derivatives, making it suitable for vegans and vegetarians.

The polymer is considered inert and non-penetrating so it is unlikely to pose a risk to women who are pregnant or breastfeeding. This is not medical advice; anyone who is expecting or nursing should clear new skincare products with a doctor first, just to be safe.

Cyclodextrin Crosspolymer does not cause photosensitivity so it can be worn day or night without increasing the skin’s reaction to sunlight.

Potential Side Effects/Adverse Reactions

Responses to topical Cyclodextrin Crosspolymer vary from person to person. The points below outline potential, though uncommon, side effects. When properly formulated most users will not experience these issues.

  • Mild transient redness or itching
  • Temporary feeling of tightness if applied without additional moisture
  • Rare allergic contact dermatitis in individuals sensitive to acrylate chemistry
  • Eye irritation if the product migrates into the eyes
  • Enhanced potency of trapped actives leading to unexpected tingling or warmth

If any negative reaction occurs stop using the product and seek advice from a qualified healthcare professional.

Comedogenic Rating

Rating: 0 / 5

Cyclodextrin Crosspolymer is a large water loving polymer that stays on the surface and forms a porous film instead of sinking into pores, so it does not trap sebum or foster the buildup that can lead to blackheads. For that reason it is considered non comedogenic and is generally suitable for skin prone to acne or breakouts. As with any ingredient the finished formula, the presence of oils, and individual skin chemistry can influence real world results.

Summary

Cyclodextrin Crosspolymer works as a film former, skin protectant and viscosity controller. Its ring shaped sugar units link into a flexible mesh that dries down to a sheer veil locking in moisture, shielding skin from daily grime and lending lotions a silky glide without heaviness.

The ingredient sits in a niche corner of cosmetic chemistry, not as ubiquitous as hyaluronic acid yet increasingly popular in modern sheet masks, primers and targeted serums where lightweight texture is a priority.

Safety studies and practical use show it to be low risk for irritation or clogging, making it a gentle option for most skin types. As always patch test any new product to ensure your skin agrees with the full formula.

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