What Is Cyclotetrapeptide-24 Aminocyclohexane Carboxylate Hcl?
Cyclotetrapeptide-24 Aminocyclohexane Carboxylate HCl is a lab made peptide, meaning it is built from a short chain of amino acids that are joined together in a very specific order. Chemists link four amino acids into a tight ring, attach an aminocyclohexane carboxylate group for extra stability, then finish the molecule as a hydrochloride salt so it dissolves easily in water based formulas.
The peptide was first explored in the early 2000s when researchers were looking for small molecules that could prompt skin to act younger. It showed promise at supporting the way skin rebuilds collagen and keeps its surface smooth, so cosmetic labs quickly adopted it for age fighting products.
Production relies on solid phase peptide synthesis, a step by step process carried out on a resin bead. Each amino acid is added, the ring is closed, the side group is attached and, finally, the finished peptide is cleaved from the resin and converted to its HCl form. This controlled, small batch method keeps impurities low and activity high.
You will most often spot Cyclotetrapeptide-24 Aminocyclohexane Carboxylate HCl in serums, firming or lifting creams, rich night moisturizers, eye creams, sheet masks and treatment ampoules aimed at smoothing lines and improving skin elasticity.
Cyclotetrapeptide-24 Aminocyclohexane Carboxylate Hcl’s Cosmetic Benefits/Uses
Its main role in a formula is skin conditioning. It helps skin feel softer and look more even by supporting natural collagen creation, boosting surface hydration and encouraging a firmer texture over time.
Who Can Use Cyclotetrapeptide-24 Aminocyclohexane Carboxylate Hcl
This peptide suits most skin types, including dry, normal, combination and oily skin, because it is lightweight and non greasy. Sensitive skin generally tolerates it well thanks to its low irritation profile, though anyone with a known allergy to peptides should proceed with caution.
The ingredient is synthetically produced so it contains no animal derivatives, making it appropriate for both vegetarians and vegans.
Current research shows no specific risk for pregnant or breastfeeding women when this peptide is applied topically in cosmetic amounts. That said, this is not medical advice and anyone who is pregnant or nursing should ask a doctor before adding new skincare products to their routine.
Cyclotetrapeptide-24 Aminocyclohexane Carboxylate Hcl does not make skin more sensitive to sunlight, so it is safe for daytime use without creating extra risk of sunburn. As always, daily sunscreen remains important for overall skin health.
Potential Side Effects/Adverse Reactions
Responses to topical Cyclotetrapeptide-24 Aminocyclohexane Carboxylate Hcl differ from person to person. The points below outline potential side effects, yet most users should not expect to experience them when the ingredient is formulated and used properly.
- Mild redness or warmth shortly after application
- Transient itching or tingling in very sensitive skin
- Rare allergic contact dermatitis in individuals reactive to peptides or formulation preservatives
- Increased sensitivity when layered with highly acidic exfoliants or strong retinoids
If any of these effects occur and persist discontinue use and seek guidance from a healthcare professional.
Comedogenic Rating
Rating: 0 / 5 – Cyclotetrapeptide-24 Aminocyclohexane Carboxylate Hcl is a tiny water soluble peptide with no oily or waxy components so it does not clog pores. It disperses evenly in aqueous bases and rinses away cleanly, leaving no residue that could trap dead skin or sebum. Because of this it is considered suitable for acne prone or breakout prone skin. In formulas that also contain heavy emollients the overall product could still feel occlusive, but the peptide itself remains non comedogenic.
Summary
Cyclotetrapeptide-24 Aminocyclohexane Carboxylate Hcl is a lab crafted four amino acid ring that conditions skin by encouraging collagen renewal, supporting surface hydration and helping skin look firmer. It does this by signaling skin cells to behave more like they did in youth which in turn smooths texture and softens fine lines.
While not as famous as peptides like Matrixyl it has carved out a niche in high end serums and eye treatments where brands want a lightweight yet active ingredient that pairs well with other anti aging staples.
Safety data shows a low risk of irritation or allergy for most users and its comedogenic rating of 0 makes it friendly for nearly all skin types. As with any new skincare ingredient it is smart to perform a small patch test before full use especially if you have a history of sensitivity.