Di-C12-15 Alkyl Dimonium Chloride: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Di-C12-15 Alkyl Dimonium Chloride?

Di-C12-15 Alkyl Dimonium Chloride is a quaternary ammonium compound made by joining two medium-chain fatty alcohols—usually derived from coconut or palm oils—to a nitrogen-based backbone, then neutralizing the mixture with hydrochloric acid to form a chloride salt. This design gives the molecule a positive charge that helps it cling to negatively charged hair fibers.

Quats like this one first appeared in hair care during the mid-20th century when chemists were looking for gentler alternatives to soap-based rinses. The C12-15 chain length was found to strike a balance between strong conditioning power and a light feel, so it quickly gained ground in salon products before moving into mass-market lines.

Manufacturing starts with fatty alcohols sourced from plant oils. These alcohols react with dimethylamine, producing a tertiary amine. The amine is then reacted with methyl chloride to “quaternize” it, locking in the permanent positive charge. The final paste or liquid can be added straight into water-based formulations.

You will most often see Di-C12-15 Alkyl Dimonium Chloride in rinse-off conditioners, deep-treatment masks, leave-in sprays, anti-frizz creams and 2-in-1 shampoos. It may also appear in some styling products that promise softness or detangling.

Di-C12-15 Alkyl Dimonium Chloride’s Cosmetic Benefits/Uses

This ingredient is valued mainly for one key role in hair care products

As a hair conditioning agent Di-C12-15 Alkyl Dimonium Chloride smooths the cuticle, reduces static, makes combing easier and leaves hair feeling softer without weighing it down. Its positive charge allows it to bind to damaged spots along the hair shaft, offering targeted conditioning that lasts through rinsing yet does not build up quickly, which helps hair look glossy and manageable

Who Can Use Di-C12-15 Alkyl Dimonium Chloride

Because it rinses away easily and does not clog pores the ingredient is generally suitable for all scalp and hair types, including oily, dry and color-treated hair. People with very sensitive or allergy-prone skin may still prefer a more minimal formula since quaternary ammonium compounds can occasionally provoke irritation on compromised skin

Most commercial grades are made from plant-derived fatty alcohols so they are usually acceptable for vegans and vegetarians. If animal origin feedstocks were used the label or supplier should specify that, so anyone following a strictly plant-based lifestyle may want to confirm the source

No data suggest that topical use during pregnancy or breastfeeding poses a risk, as the molecule is large and stays on the hair shaft rather than penetrating skin. This is not medical advice and anyone who is pregnant or nursing should show the full ingredient list of any new hair product to their healthcare provider just to be safe

Di-C12-15 Alkyl Dimonium Chloride does not make skin more sensitive to sunlight and it has no known interactions with UV exposure

Potential Side Effects/Adverse Reactions

Individual reactions to topical Di-C12-15 Alkyl Dimonium Chloride can vary. The issues listed below are possible but uncommon when the ingredient is used at standard levels in well-formulated products

  • Mild scalp irritation or redness
  • Eye stinging if the product accidentally drips into the eyes
  • Contact allergy presenting as itch or rash in people already sensitized to quaternary ammonium compounds
  • Dryness or dullness when very high concentrations are left on fine hair for extended periods

If you experience any of these effects discontinue use and consult a healthcare professional if symptoms persist

Comedogenic Rating

Rating: 0 / 5

Di-C12-15 Alkyl Dimonium Chloride is highly water dispersible and is designed to sit on hair strands rather than skin pores. It is usually used in rinse-off conditioners at low levels, so it has little chance to linger on the skin or mix with sebum. For these reasons it is considered non-comedogenic.

Suitable for those prone to acne or breakouts.

As with any hair product, residue can transfer to facial skin if not rinsed thoroughly, so a quick rinse after letting conditioner run off the face can help keep pores clear.

Summary

Di-C12-15 Alkyl Dimonium Chloride is a hair conditioning agent that smooths cuticles, cuts static and makes detangling easier. Its positive charge attracts it to damaged areas of the hair shaft, creating a thin, even layer that leaves hair soft and shiny without heavy build-up.

The ingredient is common in mainstream and salon hair care but not as famous as silicones or oils, partly because it hides in the fine print while quietly doing its job.

Overall safety data show it is well tolerated on healthy skin and scalp, with irritation or allergy being rare. As with any new product it is wise to patch test first and listen to your skin.

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