Dihydroxychalcone Disulfonic Acid: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Dihydroxychalcone Disulfonic Acid?

Dihydroxychalcone Disulfonic Acid is a man-made version of a plant molecule in the chalcone family, a group of compounds naturally found in many fruits and flowers. Chemists added two sulfonic acid groups to the original structure so it could dissolve in water and stay stable in a lotion or serum. First explored by researchers looking for gentle skin care actives in the late 1990s, it soon moved from the lab into commercial products thanks to its calming and conditioning effect on skin.

The ingredient is produced through a series of controlled reactions that link together simple aromatic building blocks, then introduce the sulfonic acid side groups. The final powder is highly water loving, making it easy to blend into water-based phases during manufacturing.

Today you will most often spot Dihydroxychalcone Disulfonic Acid in lightweight moisturizers, soothing masks, after-sun gels, redness relief serums and other leave-on treatments where a brand wants to add a comforting touch without heavy oils.

Dihydroxychalcone Disulfonic Acid’s Cosmetic Benefits/Uses

This ingredient is valued for one main job in skin care formulas

As a skin conditioning agent Dihydroxychalcone Disulfonic Acid helps the skin feel softer and look healthier. It supports the skin’s natural barrier, eases the tight feeling that can follow cleansing and can visibly reduce temporary redness from everyday stressors. Because it is water soluble it delivers this comfort without adding greasiness, so it suits both light gels and richer creams.

Who Can Use Dihydroxychalcone Disulfonic Acid

Dihydroxychalcone Disulfonic Acid is generally well tolerated by all major skin types. Its water-soluble nature means it delivers comfort without an oily residue, so oily and combination skin benefit from the light feel while dry or sensitive skin appreciate the soothing action. There are no known concerns that make it unsuitable for mature or acne-prone skin.

The ingredient is synthesized entirely from non-animal raw materials, so products featuring it are usually compatible with vegan and vegetarian lifestyles. Always check the full formula though, as other components in the finished product may differ.

No published data suggest that topical use poses a specific risk during pregnancy or breastfeeding. Still, this is not medical advice and anyone who is pregnant or nursing should show the complete product label to a qualified healthcare professional before use to be on the safe side.

Dihydroxychalcone Disulfonic Acid is not known to cause photosensitivity, so it does not make skin more prone to sunburn. Standard daytime sun protection habits should still be followed.

Potential Side Effects/Adverse Reactions

Responses to any skincare ingredient vary from person to person. The points below list potential but uncommon side effects of topical Dihydroxychalcone Disulfonic Acid when used in a properly formulated product.

  • Mild stinging or warmth especially on freshly exfoliated or compromised skin
  • Temporary redness which should subside within a few minutes of application
  • Contact dermatitis in the rare event of individual allergy to the molecule or another component in the formula
  • Eye irritation if the product migrates into the eyes

If any of these reactions persist or worsen stop using the product and consult a healthcare professional.

Comedogenic Rating

Rating: 0 / 5

Dihydroxychalcone Disulfonic Acid is a small, water-soluble molecule and contains no oily chains or waxy residues that could block pores, so it is considered non-comedogenic. Products using it usually rely on lightweight gels or emulsions that rinse cleanly from the skin, further reducing the chance of buildup.

That makes this ingredient suitable for people who are prone to acne or frequent breakouts.

Because it is almost always used at low levels and does not alter the viscosity of a formula, its presence will not change the overall pore-clogging potential of a product already designed for acne-prone skin.

Summary

Dihydroxychalcone Disulfonic Acid is included in skincare as a skin-conditioning agent that helps calm visible redness, support the skin barrier and leave the surface feeling soft and comfortable. It does this by binding water to the upper layers of skin and by offering a gentle antioxidant effect that eases signs of daily irritation.

While its benefits are sound, the ingredient is still a bit of a niche choice compared with better known soothers like panthenol or allantoin, so you will mostly find it in targeted calming serums, after-sun gels and a few dermatologist-led brands.

Current research and in-market use show a strong safety profile with very low risk of irritation or sensitization. As with any new cosmetic product it is wise to perform a quick patch test before full-face use just to confirm personal compatibility.

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