Dihydroxypropyl Dehydrolatanoprostamide: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Dihydroxypropyl Dehydrolatanoprostamide?

Dihydroxypropyl Dehydrolatanoprostamide is a lab made cousin of natural prostaglandins, a group of fat based compounds that occur in the body. Chemists first developed this analogue while exploring ingredients that could gently support hair growth and scalp comfort without the strength or rules that come with prescription drugs. The ingredient is created through a multi step process that links a dihydroxypropyl group to a modified latanoprostamide backbone. Each step is carried out in carefully controlled reactors, followed by purification so the final material meets cosmetic grade standards.

Because it is fully synthetic there is no need for animal or plant harvesting, which keeps supply steady and helps avoid allergen concerns. Brands include it in rinse off and leave in hair masks, scalp serums, targeted brow and lash boosters and high end conditioners where extra softening or a feeling of fullness is desired.

Dihydroxypropyl Dehydrolatanoprostamide’s Cosmetic Benefits/Uses

In everyday beauty items this ingredient shines in one clear role.

Hair conditioning: Dihydroxypropyl Dehydrolatanoprostamide smooths the cuticle so strands feel softer and look glossier. It can also give fine or thinning hair a slightly thicker appearance by helping each fiber hold on to moisture. When used in brow or lash formulas it coats the hairs, making them feel flexible instead of brittle which supports daily grooming and keeps breakage at bay.

Who Can Use Dihydroxypropyl Dehydrolatanoprostamide

This ingredient is considered suitable for all skin and scalp types because it is non greasy and lightweight. Dry or fragile strands benefit most from its conditioning effect while oily scalps usually tolerate it without feeling heavy. People prone to sensitivities can also use it since it contains no common fragrance or protein allergens but as always individual tolerance can vary.

Dihydroxypropyl Dehydrolatanoprostamide is made entirely in a lab and has no animal derived components so it fits vegan and vegetarian lifestyles.

No human pregnancy or lactation studies exist for this cosmetic ingredient. Although absorption through the scalp is expected to be minimal it is best for anyone who is pregnant or breastfeeding to show the full product ingredient list to a healthcare professional before use. This is informational content only and not medical advice.

The molecule does not make skin or hair more prone to sun damage so it is considered non photosensitising. It also plays nicely with common hair care actives like peptides, panthenol and plant oils so layering is straightforward.

Potential Side Effects/Adverse Reactions

Reactions to topical Dihydroxypropyl Dehydrolatanoprostamide differ from person to person. The points below outline possible but uncommon effects when the ingredient is used as directed in a finished product. Most users will not notice any of these issues.

  • Mild scalp or skin redness
  • Temporary darkening of the skin at the application site
  • Unwanted hair growth on areas that come into repeated contact with the product
  • Eye irritation if formula accidentally drips into the eyes

If any persistent discomfort or unusual change occurs stop using the product and consult a healthcare professional.

Comedogenic Rating

Rating: 1 / 5

Dihydroxypropyl Dehydrolatanoprostamide has a very low tendency to clog pores because it is used in tiny amounts, is lightweight and is often paired with water based carriers rather than heavy oils. Its molecule is designed to sit on hair shafts rather than sink into facial follicles so buildup is minimal.

Because of this low score it is generally considered suitable for acne-prone or breakout-prone skin.

Formulas that combine it with richer plant butters or waxes could raise the overall comedogenic load of the finished product, so the full ingredient list still matters.

Summary

Dihydroxypropyl Dehydrolatanoprostamide is a lab crafted prostaglandin analogue that conditions hair, lashes and brows by smoothing the cuticle, boosting moisture retention and leaving strands glossier and more flexible. It pulls off these benefits without a greasy feel and without relying on animal sourcing.

The ingredient is still something of a niche player, found mainly in premium scalp serums and targeted brow or lash treatments rather than mass market shampoos. As awareness of gentle hair-thickening actives grows its presence is expected to rise.

Current safety data shows a low risk of irritation or pore clogging for most users. As with any new cosmetic it is wise to patch test a product that contains Dihydroxypropyl Dehydrolatanoprostamide before full use, just to be on the safe side.

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