Dihydroxypropyltrimonium Chloride: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Dihydroxypropyltrimonium Chloride?

Dihydroxypropyltrimonium Chloride is a water-loving ingredient made from propylene glycol that has been reacted with trimethylamine to give it a positive charge. The result is a clear liquid that blends easily with water-based formulas. It first appeared in hair and skin products in the early 2000s when chemists were searching for milder alternatives to older conditioning agents that could feel heavy. Today it is produced in large batches through a simple reaction and purification process that keeps costs low and quality consistent.

You will spot it in leave-in hair conditioners, rinse-off masks, daily facial moisturizers, after-shave balms, light body lotions and soothing gel creams. Because it attracts water and holds it at the surface, brands often add it to formulas marketed for dry or dehydrated skin as well as products that promise a soft, smooth hair finish.

Dihydroxypropyltrimonium Chloride’s Cosmetic Benefits/Uses

This ingredient is valued for one main job in personal care products.

As a humectant, Dihydroxypropyltrimonium Chloride pulls moisture from the air and draws it toward the skin or hair. By locking in that water it helps keep skin feeling plump and supple and leaves hair looking smoother with less static. Its lightweight feel means it delivers hydration without the greasy after-feel some heavier ingredients create, making it a popular choice in modern, fast-absorbing formulas.

Who Can Use Dihydroxypropyltrimonium Chloride

This humectant is gentle enough for most skin types including dry, oily and combination skin. Its light texture makes it a good pick for acne-prone complexions that shy away from heavy creams while its water-binding ability helps relieve tight, flaky areas on very dry or mature skin. Sensitive skin generally tolerates it well because it lacks fragrance and harsh solvents.

Dihydroxypropyltrimonium Chloride is synthesized from petrochemical sources not animal by-products, so it is suitable for vegans and vegetarians. Most manufacturers also list it as cruelty-free since its safety data come from established in-vitro and human patch studies rather than ongoing animal tests.

The molecule is not known to interfere with pregnancy or lactation but because hormonal skin shifts can make reactions less predictable, pregnant or breastfeeding individuals should still review any new skincare with their healthcare provider. This information is educational and not medical advice.

The ingredient does not absorb UV light or make skin more prone to sunburn, so it is not considered photosensitizing. It works well alongside common actives like niacinamide and panthenol and does not affect sunscreen performance.

Potential Side Effects/Adverse Reactions

  • Mild redness or stinging on very compromised skin
  • Transient itching or tightness if layered with multiple strong actives
  • Contact dermatitis in individuals with a specific allergy to quaternary ammonium compounds
  • Eye irritation if the product accidentally runs into the eyes
  • Build-up on fine hair leading to a weighed-down feel if used in high-concentration leave-ins

If you experience any of the above discontinue use and seek medical advice if symptoms persist or worsen.

Comedogenic Rating

Rating: 0 (non-comedogenic). Dihydroxypropyltrimonium Chloride is a small water-soluble molecule that rinses off easily and leaves no oily residue behind, so it does not clog pores or trap dead skin cells. Its positive charge helps it bind to the surface then rinse clean without forming a film that could block follicles. Because of this it is generally suitable for acne-prone or breakout-prone skin. In leave-on products very high concentrations are uncommon and even then the lightweight nature of the ingredient makes pore blockage unlikely.

Summary

Dihydroxypropyltrimonium Chloride works as a humectant, drawing water from the air and binding it to skin or hair to improve softness suppleness and static control. It carries a positive charge that helps it deposit lightly on the surface while its water solubility prevents buildup, which is why formulators use it in light lotions gels and conditioners.

The ingredient is reasonably popular in modern hair care and growing in skincare although it has not reached the mainstream status of glycerin or hyaluronic acid. Brands appreciate its low cost and gentle sensory feel which makes it easy to slip into everyday products.

Overall safety data show a low risk of irritation or sensitization when used at cosmetic levels. As with any new product it is wise to perform a quick patch test first to make sure your individual skin tolerates the full formula.

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