Dimethicone/Aminopropyl Silsesquioxane Copolymer: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Dimethicone/Aminopropyl Silsesquioxane Copolymer?

Dimethicone/Aminopropyl Silsesquioxane Copolymer is a silicone-based ingredient created by linking three building blocks: methyl triethoxysilane, aminopropyl triethoxysilane and dimethyl siloxane. These pieces join together in a branched network that feels light and silky to the touch. Silicones first entered the beauty world in the 1950s for their smooth, water-resistant finish. Over time chemists tweaked basic dimethicone to add extra benefits, and this copolymer is one of those upgrades. Its production involves controlled hydrolysis and condensation of the silane monomers followed by blending with dimethyl siloxane, forming a stable polymer that disperses well in water-based or oil-based formulas. You will usually spot it in rinse-off and leave-on hair products such as conditioners, masks, serums, smoothing creams and color-protecting treatments where a soft feel and lasting slip are desired.

Dimethicone/Aminopropyl Silsesquioxane Copolymer’s Cosmetic Benefits/Uses

This ingredient is prized for its hair conditioning ability. It forms a thin film along each strand that smooths rough cuticles, reduces frizz, adds shine and makes detangling easier. The film stays flexible so hair does not feel weighed down, and its mild water resistance helps lock in moisture for a softer, healthier look after styling or washing.

Who Can Use Dimethicone/Aminopropyl Silsesquioxane Copolymer

This ingredient is considered gentle enough for all skin and scalp types including dry, oily and sensitive because its molecules sit on the surface rather than penetrating deeply. On hair it suits every texture from fine and straight to coarse and tightly curled since the flexible film it forms is lightweight and non stiffening. People following vegan or vegetarian lifestyles can typically use it because it is produced synthetically from silica-derived sources with no animal by-products involved; however cruelty policies vary by brand so checking a company’s stance on animal testing is still worthwhile.

Current research shows no reproductive toxicity and practically zero systemic absorption so products containing this copolymer are generally viewed as safe for women who are pregnant or breastfeeding. This is not medical advice and anyone who is expecting or nursing should clear any new personal care item with a qualified physician to be safe.

Dimethicone/Aminopropyl Silsesquioxane Copolymer does not increase photosensitivity and can be used day or night without extra sun precautions. It is also color safe and will not strip dyes or chemical treatments.

Potential Side Effects/Adverse Reactions

Reactions to topical Dimethicone/Aminopropyl Silsesquioxane Copolymer vary from person to person. The points below outline potential but uncommon issues. When the ingredient is formulated correctly most people experience none of these effects.

Mild scalp irritation or redness in sensitive individuals

Rare allergic contact dermatitis triggered by the amino functional group

Product buildup that can make hair appear dull or heavy if used in excess or without clarifying shampoos

Breakouts along the hairline for very acne-prone users when residue is not cleansed properly

Eye stinging or watering if the product accidentally runs into the eyes before rinsing

If any negative reaction occurs stop using the product and seek advice from a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 1/5. Dimethicone/Aminopropyl Silsesquioxane Copolymer is a large, inert silicone molecule that sits on the surface and is highly unlikely to clog pores. The slight presence of an amino group could make it marginally more interactive than plain dimethicone, yet the overall molecule remains too big and too non-greasy to lodge inside follicles. It is generally suitable for acne-prone or breakout-prone skin, especially when rinsed off as part of a hair product. Only in rare cases of heavy residue left on the skin might it contribute to congestion, so thorough cleansing around the hairline is wise.

Summary

Dimethicone/Aminopropyl Silsesquioxane Copolymer is a silicone-based hair conditioner that smooths cuticles, reduces frizz, boosts shine and helps hair retain moisture by forming a flexible, breathable film. Chemists blend methyl and aminopropyl silanes with dimethyl siloxane to create a branched polymer that disperses easily in both water and oil phases, giving formulators versatility without weighing hair down.

The ingredient is fairly popular in modern conditioners, masks and leave-ins although it flies under the radar because its name rarely appears on front labels. It offers salon-level slip and softness with minimal buildup when used as directed.

Current safety data show low irritation potential, negligible absorption and no known reproductive or photo-reactive concerns. As with any cosmetic ingredient individual sensitivities vary so patch testing a new product is a smart precaution.

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