Dinonoxynol-9 Citrate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Dinonoxynol-9 Citrate?

Dinonoxynol-9 Citrate is a lab made ingredient formed when di(polyethylene glycol 450 nonyl phenyl ether) is reacted with citric acid. The result is a large, water loving molecule that mixes oil and water with ease. Its roots trace back to the late 1970s when chemists searched for gentler ways to clean skin without harsh soaps. Over time the compound was refined and adapted for personal care, finding a steady place in modern formulations.

Production starts with nonylphenol, a substance derived from petroleum. Through a process called ethoxylation, many units of ethylene oxide are added to create a long polyethylene glycol chain. This chain is then joined with citric acid to improve water solubility and skin compatibility. The finished material looks like a thick, clear liquid that blends smoothly into creams and gels.

Thanks to its dual love for oil and water, Dinonoxynol-9 Citrate appears in a variety of products. You can spot it in facial cleansers, micellar waters, exfoliating masks, lightweight moisturizers and even leave-on treatments aimed at balancing oily skin. It is favored in formulations where a gentle cleanse and stable texture are needed.

Dinonoxynol-9 Citrate’s Cosmetic Benefits/Uses

This ingredient brings two main technical talents to a formula, both of which improve how a product feels and performs on the skin.

  • Cleansing: Its structure grabs onto dirt, excess oil and makeup then lifts them away when you rinse. This allows formulators to create washes and wipes that clean effectively without leaving skin tight or dry.
  • Emulsifying: By holding oil and water together it keeps creams, lotions and gels from separating. This ensures a smooth, even texture so every pump or scoop delivers the same balanced mix of active ingredients.

Who Can Use Dinonoxynol-9 Citrate

Because this ingredient is both water loving and mild it generally works well for normal, oily and combination skin. Dry or very sensitive skin can also tolerate it in most cases, though those users may prefer formulas where Dinonoxynol-9 Citrate sits lower on the ingredient list to avoid any possible tightness.

The compound is synthetic and contains no materials of animal origin so it is suitable for vegans and vegetarians. It is often made in facilities that follow standard cosmetic good manufacturing practices yet anyone with strict lifestyle rules may still want to confirm brand specific sourcing.

Current data shows no direct risks for women who are pregnant or breastfeeding when this ingredient is applied to intact skin. That said this is not medical advice and anyone expecting or nursing should run all skincare choices by a qualified doctor to be safe.

Dinonoxynol-9 Citrate does not make skin more prone to sunburn so extra photosensitivity is not a concern. It also plays well with most other common skincare ingredients which helps it fit into simple or complex routines alike.

Potential Side Effects/Adverse Reactions

Reactions can vary from person to person. The points below list potential side effects tied to topical use of Dinonoxynol-9 Citrate. These issues are uncommon for the average user when the product has been properly formulated.

  • Mild skin redness or stinging, most likely in very sensitive or damaged skin
  • Transient dryness if used in high amounts or left on for prolonged periods
  • Eye irritation when the product is rinsed off poorly around the eye area
  • Rare allergy presenting as itching or small bumps

If any discomfort or irritation develops stop using the product and consult a healthcare professional if symptoms persist.

Comedogenic Rating

Rating: 1 (very low likelihood of clogging pores)

Dinonoxynol-9 Citrate is a highly water soluble surfactant that rinses clean without leaving a heavy film on skin. Its large hydrophilic structure prevents it from settling into pores which keeps the risk of blockage minimal. Because it is used at modest concentrations and is typically washed off, breakouts are unlikely for most users.

Acne-prone individuals can generally use products containing this ingredient without added concern, especially in rinse-off formulas.

No reports link it to fungal acne flare-ups, and it does not interact with sebum in a way that would fuel Malassezia growth.

Summary

Dinonoxynol-9 Citrate serves mainly as a gentle cleanser and a reliable emulsifier. Its oil-grabbing head binds grime while its water-loving tail lets everything rinse away clean which leaves skin refreshed rather than stripped. In creams and gels it keeps oil and water phases blended so the texture stays smooth throughout a product’s shelf life.

The ingredient is not a household name yet it enjoys steady use in specialty cleansers micellar waters and lightweight moisturizers where a mild touch is prized. Formulators appreciate its versatility but it has not reached the mainstream popularity of classic surfactants like sodium laureth sulfate.

Current safety data label it as low risk with only rare irritation in very sensitive skin. Still, whenever you try a new product it is smart to do a quick patch test to confirm personal compatibility.

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