Dioctyldodecyl Lauroyl Glutamate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Dioctyldodecyl Lauroyl Glutamate?

Dioctyldodecyl Lauroyl Glutamate is a specialty ester derived from the amino acid L-glutamic acid, lauric acid obtained from coconut or palm kernel oil, and long chain branched alcohols made from vegetable sources. The finished molecule is an oil-soluble powder or wax that melts easily into cosmetic bases, giving it versatility in both waterless and emulsion formulas.

The ingredient emerged in the early 2000s when formulators began looking for gentle plant-based alternatives to traditional fatty alcohols and silicones. By combining glutamic acid with lauric acid, chemists created a molecule that mimics parts of the skin’s natural lipids while delivering a soft velvety feel. Today it is produced through a two-step process: first lauric acid is reacted with glutamic acid to form lauroyl glutamate, then two octyldodecyl groups are esterified onto the molecule to boost its spreading and conditioning performance.

You will most often see Dioctyldodecyl Lauroyl Glutamate in creamy cleansers, hydrating toners, lightweight moisturizers, hair conditioners, leave-in treatments, solid cleansing bars, makeup primers and some sunscreen bases. Its ability to enhance texture and replenish surface lipids makes it popular in both rinse-off and leave-on products aimed at sensitive or dry skin.

Dioctyldodecyl Lauroyl Glutamate’s Cosmetic Benefits/Uses

This ingredient brings several complementary benefits that improve the feel and performance of personal care formulas.

  • Hair conditioning: Forms a thin lubricating layer along the hair shaft that smooths cuticles, reduces static and makes detangling easier without weighing strands down
  • Skin conditioning: Acts as a surface lipid replenisher that softens rough patches, enhances suppleness and leaves a silky afterfeel
  • Emollient: Fills in microscopic gaps in the skin barrier to prevent moisture loss while giving formulas a plush slip that rivals lightweight silicones
  • Cleansing: Helps dissolve makeup oils and daily grime yet remains mild, so it supports a gentle cleansing action that does not strip skin or hair

Who Can Use Dioctyldodecyl Lauroyl Glutamate

This multitasking ester is considered friendly to nearly all skin types. Dry and mature skin benefit from its emollient cushioning, sensitive skin appreciates its mildness, and oily or combination skin enjoy its light non greasy finish that will not clog pores. There are no inherent qualities that make it unsuitable for particular skin types, though individuals with a known intolerance to fatty acids should proceed with caution.

The raw materials come from plant sources and the molecule contains no animal derived components, so products formulated with it are generally suitable for vegans and vegetarians. As always, check the full ingredient list because other ingredients in the same product may not meet vegan standards.

No data suggest a specific risk for pregnant or breastfeeding women when this ingredient is applied topically in cosmetic concentrations. Still, this is not medical advice and anyone who is pregnant or nursing should review any new skincare product with a qualified healthcare professional to be safe.

Dioctyldodecyl Lauroyl Glutamate is not known to cause photosensitivity and can be used in both day and night routines without heightening sun sensitivity. It is also color safe, making it appropriate for chemically treated hair.

Potential Side Effects/Adverse Reactions

Reactions to topical Dioctyldodecyl Lauroyl Glutamate differ from person to person. The points below outline potential side effects that are uncommon and should not represent the typical experience when the ingredient is used at approved levels in well formulated products.

  • Mild skin irritation such as slight redness or itching, mainly in individuals with highly reactive skin
  • Rare allergic contact dermatitis for those specifically sensitized to glutamate based compounds
  • Transient eye stinging if the product accidentally gets into the eyes
  • Build up on very fine hair that may lead to a weighed down feel if used in heavy leave in conditioners without periodic clarifying

If you notice any discomfort or unexpected reaction discontinue use and seek guidance from a medical professional or dermatologist.

Comedogenic Rating

Rating: 1 / 5. Dioctyldodecyl Lauroyl Glutamate has a branched structure that spreads thinly on skin and absorbs without leaving a heavy film, so it is far less likely to block pores than straight chain oils or waxes. Current lab and consumer data report very few instances of pore clogging or acne flare-ups, making it generally suitable for people prone to breakouts. Because it is oil soluble it can mingle with sebum yet its lightweight nature and rapid absorbency keep it from sitting in pores long enough to harden or trap debris.

No noteworthy interactions with common acne treatments like benzoyl peroxide or salicylic acid have been flagged, and it rinses off readily with standard cleansers.

Summary

Dioctyldodecyl Lauroyl Glutamate acts as a skin and hair conditioner, emollient and mild cleanser all in one. Its amino acid backbone mimics natural skin lipids, while the lauric and octyldodecyl groups give it slip that softens surfaces and reduces moisture loss. When used in shampoo or face wash it lifts away grime without stripping, and in creams or serums it leaves a silky veil that smooths rough patches and calms flyaways.

The ingredient enjoys a quiet but steady popularity, especially in Japanese and Korean formulations that prize elegant textures. It has not hit the mainstream buzz of hyaluronic acid or niacinamide yet seasoned formulators value it for its gentle performance and plant based origin.

Safety profiles show a low irritation risk and minimal comedogenic potential. Still, whenever you introduce a new product that contains this ester it is wise to patch test first to make sure your skin agrees with the full formula.

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