What Is Dipeptide-7?
Dipeptide-7 is a lab made two-amino-acid chain built from lysine and threonine. Because it does not occur naturally in plants or animals it is produced entirely in controlled laboratory settings. Chemists link the two amino acids together through a process called solid phase peptide synthesis, then purify the result so it can be mixed safely into skincare formulas.
Peptides began turning heads in beauty labs in the early 2000s when research showed they could signal the skin to behave in a healthier way. Dipeptide-7 soon joined the line-up thanks to its small size and skin friendly building blocks. Its clean, consistent makeup also makes it less likely to cause irritation compared with larger, more complex molecules.
You will most often see Dipeptide-7 in lightweight anti-aging serums, eye creams, daily moisturizers, sheet masks and leave-on gels meant to calm freshly treated skin. Brands favor it when they want to add a touch of soothing support without weighing the formula down.
Dipeptide-7’s Cosmetic Benefits/Uses
Dipeptide-7 is valued mainly for one key job in skincare.
Skin conditioning: This peptide helps keep the surface of the skin soft, smooth and comfortable. By supporting the skin’s natural barrier it can reduce the feeling of dryness, add a supple look and make other moisturizing ingredients work more effectively within the formula.
Who Can Use Dipeptide-7
Dipeptide-7 is considered suitable for all common skin types including normal, dry, oily and combination because it focuses on gentle skin conditioning without adding heavy oils or aggressive actives. Sensitive skin usually tolerates it as well since the peptide is small and highly purified, though individuals with a known sensitivity to peptides or any component in the finished formula should approach with caution.
The ingredient is entirely lab made and contains no animal derived materials which makes it appropriate for both vegans and vegetarians.
No research points to specific concerns for pregnant or breastfeeding women when using Dipeptide-7 topically. That said this is not medical advice and anyone who is pregnant or nursing should review new skincare products with a qualified healthcare professional to be extra safe.
Dipeptide-7 does not make skin more prone to sun damage so it is not considered photosensitising. Standard daily sun protection is still recommended to guard against routine UV exposure.
Potential Side Effects/Adverse Reactions
Responses to topical Dipeptide-7 differ from person to person. The effects listed below are possible but unlikely for most users when the ingredient is formulated correctly and used as directed.
- Mild redness or warmth shortly after application
- Transient stinging or tingling on very sensitive skin
- Localised itching or dryness if the formula also contains strong preservatives or fragrances
- Allergic contact dermatitis in individuals with a peptide allergy
If any of these reactions occur stop using the product and consult a healthcare professional for personalised guidance.
Comedogenic Rating
Rating: 0/5
Dipeptide-7 is a tiny, water soluble peptide with no oils, waxes or heavy silicones that could clog pores. Because it sits lightly on the skin and rinses away easily during cleansing, it earns the lowest possible comedogenic score. This makes it a comfortable choice for people prone to acne or frequent breakouts. No studies or case reports link the ingredient to increased comedones or blackheads, even in leave-on formulas.
Formulators sometimes pair Dipeptide-7 with richer emollients to boost moisture; in that case the overall product, not the peptide itself, could be the pore-clogging culprit. Always check the full ingredient list if you are monitoring comedogenicity closely.
Summary
Dipeptide-7 is a lab crafted two-amino-acid peptide that conditions skin by supporting its natural barrier, helping it stay soft, smooth and comfortably hydrated. Its small size allows it to nestle easily into lightweight serums, creams and masks without adding heft or irritation.
The peptide enjoys modest popularity: it is not as famous as retinol or hyaluronic acid, yet formulators appreciate its gentle touch and compatibility with most skin types so its presence is steadily growing in modern skincare lines.
Safety data show a low risk of side effects, and the ingredient is vegan friendly with no known concerns for pregnancy or photosensitivity. As with any new skincare ingredient it is wise to perform a quick patch test before full use to confirm personal tolerance.