Dipropylene Glycol Salicylate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Dipropylene Glycol Salicylate?

Dipropylene Glycol Salicylate is a synthetically produced ester that combines salicylic acid with dipropylene glycol. On a chemistry chart it appears as 2-(2-hydroxypropyl)-1-methylethyl salicylate, but in everyday terms it is a clear liquid that blends easily with both water and oil. The ingredient does not come from a plant or animal source; it is made in a lab through an esterification process where salicylic acid reacts with dipropylene glycol under controlled heat and the presence of a catalyst. This method lets chemists tailor purity levels so the final material is gentle enough for skin care.

Salicylate esters have been explored for personal care since the mid 1900s when formulators noticed their smooth glide and light scent helped improve the feel of creams and lotions. Over time Dipropylene Glycol Salicylate stood out for offering the conditioning qualities of salicylates without the strong medicinal odor of classic salicylic acid. Today you may spot it in moisturizers, lightweight lotions, sheet masks, rinse off cleansers, toners, after shave balms and even some hair conditioners where it helps the formula stay silky and stable.

Dipropylene Glycol Salicylate’s Cosmetic Benefits/Uses

This versatile ester plays several roles in modern skin and hair care formulas

  • Skin Conditioning: Leaves a soft hydrated feel on the surface which can make the skin appear smoother and more supple
  • Emollient: Forms a light layer that fills in tiny cracks in the skin barrier helping reduce water loss and improving overall comfort without a greasy finish
  • Cleansing: Acts as a mild solvent that helps lift away dirt oil and leftover makeup allowing cleansers to rinse more thoroughly
  • Tonic: Provides a refreshing sensation that can leave skin feeling revived after application useful in toners and after shave products
  • Viscosity Controlling: Helps fine tune thickness so lotions stay pumpable, serums flow smoothly and masks spread evenly across the face

Who Can Use Dipropylene Glycol Salicylate

Because it is a light, non-occlusive ester, Dipropylene Glycol Salicylate tends to agree with normal, dry and combination skin. It offers slip and softness without leaving a heavy film so mildly oily skin often tolerates it as well. People with very reactive or salicylate-allergic skin should approach with caution since any salicylate derivative can trigger redness or itching in that small group.

The ingredient is made entirely in a laboratory using petrochemical feedstocks so it contains no animal material. This makes it suitable for vegans and vegetarians when used in a formula that is otherwise free of animal-derived additives.

Current cosmetic safety reviews have found no evidence that topical Dipropylene Glycol Salicylate poses a risk to pregnant or breastfeeding women at the tiny levels used in skincare. That said, research during pregnancy is limited. This is not medical advice and anyone who is expecting or nursing should check with a healthcare professional before adding new products, just to be safe.

Unlike some essential oils or citrus extracts, Dipropylene Glycol Salicylate does not cause photosensitivity. Normal sun protection habits are still recommended because healthy skin always benefits from daily sunscreen but extra precautions are not needed solely because a product contains this ester.

Potential Side Effects/Adverse Reactions

Side effects from topical Dipropylene Glycol Salicylate vary from person to person. The points below describe potential reactions yet most users will not experience them when the ingredient is formulated and used as intended.

  • Skin irritation – mild stinging or burning, usually in very sensitive complexions
  • Redness or flushing – temporary increased blood flow to the area after application
  • Dry patches – overuse can disrupt the moisture barrier in some individuals
  • Allergic contact dermatitis – rare rash, swelling or itching in people with salicylate or aspirin allergy
  • Increased sensitivity when combined with strong acids or retinoids – layering multiple active ingredients may heighten irritation

If any of these reactions develop, stop using the product and seek advice from a qualified healthcare provider.

Comedogenic Rating

Rating: 1 / 5

Dipropylene Glycol Salicylate is a small, water- and oil-miscible ester that sinks in quickly rather than sitting on the surface and clogging pores. It lacks the long fatty chains that usually drive up comedogenicity scores, so it is unlikely to trap sebum or dead cells inside follicles. Its solvent nature can even help thin out thicker oils in a formula, lowering the overall pore-blocking potential of the finished product.

Because of this low score, the ingredient is generally considered suitable for those who are prone to acne or breakouts.

Real-world results still depend on the entire formula, the percentage used, and individual skin chemistry, so a product containing this ester could feel heavier or lighter based on the other ingredients around it.

Summary

Dipropylene Glycol Salicylate works as a skin conditioner, emollient, mild cleanser, tonic and viscosity controller. Its light ester structure smooths rough patches, forms a thin comfort layer that limits water loss, helps dissolve grime for cleaner rinsing, adds a refreshing feel to toners and aftershaves, and keeps lotions and serums flowing at just the right thickness.

Although not a headline ingredient, it shows up quietly in moisturizers, cleansers and masks where formulators need a gentle multitasker that will not change the scent or weight of the product. Its behind-the-scenes role means it is not as famous as hyaluronic acid or niacinamide, but it is valued for adding slip and stability without fuss.

Safety reviews find it well tolerated at the low levels used in cosmetics with irritation or allergy being uncommon and mostly limited to people sensitive to salicylates. As with any new skincare product, patch test on a small area first to confirm your skin gets along with the full formula.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search