Disodium Azelate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Disodium Azelate?

Disodium Azelate is the sodium salt of azelaic acid, a nine-carbon dicarboxylic acid that occurs naturally in grains such as wheat rye and barley. In its cosmetic grade form the ingredient appears as a white powder that dissolves in water, creating a solution that helps chemists fine-tune the texture of a formula.

Azelaic acid itself has been studied since the 1970s for skin applications. As formulators looked for ways to harness its properties in water-based products they developed salt forms like disodium azelate that are easier to work with, have a higher pH compatibility and are less likely to crystallize in finished products.

Commercial production starts with plant-derived fatty acids that are oxidatively cleaved to yield azelaic acid. The acid is then neutralized with sodium carbonate or sodium hydroxide producing disodium azelate. The resulting ingredient is highly purified filtered then dried into a free-flowing powder.

You will typically find disodium azelate in lightweight moisturizers, gel creams, face masks, clarifying toners and leave-on treatments aimed at refining skin texture. Because of its ability to influence thickness it is also used in sunscreens, serums and body lotions where a silky non-greasy feel is desired.

Disodium Azelate’s Cosmetic Benefits/Uses

In skin care formulations disodium azelate serves one main purpose that can make a noticeable difference in how a product feels and performs on the skin.

Function: Viscosity controlling. By adjusting the thickness of a formula this ingredient helps brands create textures that spread easily yet stay put once applied. A properly balanced viscosity makes a serum drip-proof keeps a lotion from feeling runny and ensures suspended actives remain evenly distributed throughout the product for consistent results with every use.

Who Can Use Disodium Azelate

Disodium Azelate is generally well tolerated by all skin types, including normal, dry, oily, combination and acne prone. Its salt form is less likely to cause irritation than free azelaic acid making it a gentle option for sensitive skin too. Those with extremely compromised or broken skin should proceed cautiously because any salt can sting on open lesions.

The ingredient is synthetically produced from plant derived fatty acids and is not processed with animal byproducts which makes it suitable for both vegans and vegetarians.

Pregnant and breastfeeding women can usually use products containing Disodium Azelate since current research has found no link between topical application and systemic risk. This is not medical advice and anyone who is pregnant or nursing should confirm product choices with their healthcare provider just to be safe.

Disodium Azelate does not increase photosensitivity. Daily sun protection is still recommended for overall skin health but the ingredient itself does not make skin more reactive to sunlight.

Potential Side Effects/Adverse Reactions

Responses to topical Disodium Azelate differ from person to person. The following are potential side effects that could occur even though most users will not experience them when the ingredient is used at appropriate levels in a well formulated product.

  • Mild stinging or burning
  • Temporary redness
  • Dryness or flaky patches
  • Itching
  • Contact dermatitis in individuals with a known sensitivity to azelaic compounds

If irritation or any other adverse reaction develops discontinue use immediately and consult a healthcare professional

Comedogenic Rating

Rating: 0 / 5

Disodium Azelate is highly water-soluble and does not leave an oily or waxy residue on the skin, making it very unlikely to block pores. Its molecular structure is similar to azelaic acid, which is considered non-comedogenic in clinical literature. Because it functions mainly as a viscosity controller and is used at low concentrations, its ability to contribute to breakouts is virtually nil.

That means the ingredient is generally suitable for acne-prone or congestion-prone skin types.

Keep in mind overall pore-clogging potential depends on the full formula. A product packed with heavy oils could still cause breakouts even if Disodium Azelate itself does not.

Summary

Disodium Azelate is the sodium salt of azelaic acid that formulators rely on to fine-tune texture and thickness. By modulating viscosity it helps creams feel silky, stops serums from dripping and keeps active ingredients evenly distributed so each pump delivers consistent performance.

It is a behind-the-scenes workhorse rather than a headline-grabbing active, so you will not see it called out on many product labels. Still, its compatibility with a wide pH range and skin-friendly profile have made it a quiet favorite in lightweight moisturizers, sunscreens and leave-on treatments.

Safety data shows a very low risk of irritation or comedogenicity when used as intended, even for sensitive or acne-prone skin. As with any new skincare ingredient, do a simple patch test when trying a fresh product to make sure your skin responds well.

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