Disodium Cupheamido Mipa-Sulfosuccinate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Disodium Cupheamido Mipa-Sulfosuccinate?

Disodium Cupheamido MIPA-Sulfosuccinate is a plant-derived surfactant made from the fatty acids found in the seed oil of a hybrid Cuphea plant (Cuphea viscosissima crossed with Cuphea lanceolata). Chemists combine these fatty acids with mono-isopropanolamine (MIPA) to create an amide, attach part of a sulfosuccinic acid molecule, then neutralize the mix with sodium to give the final mild, water-soluble salt. The result is a gentle cleansing agent with a touch of natural origin that fits today’s push for biodegradable ingredients.

Cuphea oil entered the cosmetic scene in the early 2000s when formulators looked for sustainable options to replace coconut and palm sources. Its unusual mix of medium-chain fatty acids made it a good backbone for new sulfate-free surfactants. Disodium Cupheamido MIPA-Sulfosuccinate soon found a place in rinse-off products that needed a soft feel without harshness.

You will spot this ingredient most often in sulfate-free or low-foam shampoos, facial cleansers, body washes, bubble baths, micellar waters, makeup removers, baby washes and even some shaving creams. Because it boosts foam while staying mild, it is also added to spa-style masks and scrub cleansers that need a creamy lather.

Disodium Cupheamido Mipa-Sulfosuccinate’s Cosmetic Benefits/Uses

This versatile surfactant supports several key roles in modern formulas

  • Cleansing: Lifts away dirt, excess oil and leftover makeup while keeping the skin’s natural barrier feeling comfortable so users get a clean but not stripped finish
  • Emulsifying: Helps water and oil blend smoothly which stabilizes creamy cleansers and keeps rinse-off masks from separating on the shelf
  • Foam boosting: Improves the quantity and stability of lather letting sulfate-free shampoos and washes satisfy consumers who still want bubbles

Who Can Use Disodium Cupheamido Mipa-Sulfosuccinate

This mild surfactant is generally well tolerated by all skin types including dry sensitive and oily skin because it cleanses without stripping the barrier. Those with compromised or very reactive skin can still benefit thanks to its low irritation potential, though they should check the entire formula for other triggers.

The ingredient is derived from plant seed oil and contains no animal-origin substances or by-products so it is suitable for both vegans and vegetarians.

Current data show no specific risks for pregnant or breastfeeding women when the ingredient is used topically in rinse-off or leave-on products. That said this information is not medical advice and anyone who is pregnant or nursing should review any skincare product with their healthcare provider to be safe.

Disodium Cupheamido MIPA-Sulfosuccinate does not make skin more sensitive to the sun so it is not considered a photosensitiser. It is also biodegradable which appeals to users looking for eco-conscious choices.

Potential Side Effects/Adverse Reactions

Reactions to topical Disodium Cupheamido MIPA-Sulfosuccinate vary from person to person. The effects listed below are possible not probable, and most people will not experience them when the ingredient is used correctly in a finished cosmetic product.

  • Mild skin irritation such as redness or stinging, more likely on compromised or very sensitive skin
  • Eye irritation if the product splashes directly into the eyes
  • Allergic contact dermatitis in individuals with a specific allergy to the compound or other formula components
  • Dryness or tightness if used in a high-foaming formula on already dehydrated skin

If any of these effects occur stop using the product and seek advice from a medical professional or pharmacist.

Comedogenic Rating

Rating: 0 / 5 (non-comedogenic)

Disodium Cupheamido MIPA-Sulfosuccinate is a water-soluble surfactant that rinses off cleanly and leaves no oily residue that could clog pores. Its molecular structure is bulky and charged, meaning it stays in the water phase rather than depositing on skin or inside follicles. Because it is typically used in wash-off products any brief contact it has with the skin is further reduced by dilution and rinsing. For these reasons formulators consider it non-comedogenic.

Suitable for acne-prone or breakout-prone skin.

Formulas that pair this ingredient with heavier oils or butters could still feel occlusive so the total composition of a product matters more than this single surfactant.

Summary

Disodium Cupheamido MIPA-Sulfosuccinate acts as a gentle cleanser, emulsifier and foam booster. Its plant-derived fatty acid tail grabs oil and debris while the sulfosuccinate head bonds with water, allowing grime to lift away easily. In emulsions it keeps oil and water evenly mixed and in shampoos or washes it adds a satisfying creamy lather without harsh sulfates.

The ingredient is not as mainstream as coconut or palm-based surfactants but its mildness and sustainable backstory have earned it a steady following in sulfate-free shampoos, baby washes and sensitive skin cleansers.

Overall safety data show low irritation potential with virtually no comedogenic risk. As with any new skincare product it is wise to patch test first to make sure the entire formula agrees with your skin.

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