Disodium Hydroxyethylamino Bismethylphosphonate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Disodium Hydroxyethylamino Bismethylphosphonate?

Disodium Hydroxyethylamino Bismethylphosphonate is a lab made compound that belongs to the family of phosphonates. Chemically it is the sodium salt of [(2-hydroxyethyl)imino]dimethylene bisphosphonic acid. The molecule carries two phosphonate groups that excel at grabbing on to trace metals such as iron or copper. Because the ingredient is produced entirely through controlled industrial reactions no animal or plant matter is involved.

The material was first explored in the 1970s for water treatment where stopping scale and rust is vital. Formulators soon noticed the same metal binding skill could keep cosmetic products looking fresh and stable. Today it is manufactured by reacting phosphorous acid with formaldehyde and 2-aminoethanol, then neutralizing the result with sodium hydroxide to give the stable disodium salt. Careful filtration and drying steps yield a white to off white powder that dissolves easily in water based formulas.

You will most often find Disodium Hydroxyethylamino Bismethylphosphonate in moisturizers, serums, anti aging creams, sheet masks, sunscreens, hair conditioners and color safe shampoos. Any product that needs to stay clear, avoid discoloration or remain active for a long shelf life can benefit from its presence.

Disodium Hydroxyethylamino Bismethylphosphonate’s Cosmetic Benefits/Uses

Its value in beauty products comes from a single but important job

As a chelating agent it latches on to unwanted metal ions that can sneak into a formula through water, raw materials or packaging. By trapping these metals it helps prevent changes in color, texture or scent, keeps preservatives working as they should and protects delicate ingredients like vitamins from breaking down. The end result is a product that stays effective and pleasant to use for its full intended shelf life.

Who Can Use Disodium Hydroxyethylamino Bismethylphosphonate

This ingredient is considered gentle enough for every skin type including dry, oily, combination, sensitive and mature. Because it does not sit on the skin or form an occlusive film it will not clog pores or worsen acne prone complexions.

Disodium Hydroxyethylamino Bismethylphosphonate is made entirely from synthetic raw materials so it contains no animal derived substances. That makes it a suitable choice for vegans and vegetarians who wish to avoid ingredients sourced from animals.

Current safety data shows no specific risks for women who are pregnant or breastfeeding when the ingredient is used in a finished cosmetic. Systemic absorption is minimal. Still, this is not medical advice and anyone who is pregnant or nursing should ask a qualified doctor before starting any new skincare product just to play it safe.

The molecule does not increase sensitivity to sunlight and can be paired with daytime or nighttime products without raising the risk of sunburn. It also works across a broad pH range so it rarely conflicts with other common actives such as vitamin C, niacinamide or retinoids.

Potential Side Effects/Adverse Reactions

Responses to topical Disodium Hydroxyethylamino Bismethylphosphonate vary from person to person. The effects listed below are possible but uncommon when the ingredient is used at the low percentages found in cosmetics that have been formulated correctly.

  • Mild stinging or itching on very sensitive skin
  • Transient redness that subsides after rinsing
  • Rare cases of contact dermatitis for individuals already allergic to phosphonate compounds
  • Eye irritation if the product accidentally gets into the eyes

If any of these reactions occur discontinue use immediately and consult a healthcare professional for guidance.

Comedogenic Rating

Rating: 0/5

Disodium Hydroxyethylamino Bismethylphosphonate is a water-soluble chelating agent that does not leave an oily or occlusive residue on the skin. Because it is used at very low concentrations and quickly rinses or absorbs away with the rest of the formula it has no tendency to block pores or trap sebum, earning it a solid non-comedogenic score.

This makes the ingredient suitable for people who are prone to acne or breakouts.

No special concerns related to pore clogging have been reported in the available literature or by formulators.

Summary

Disodium Hydroxyethylamino Bismethylphosphonate is a synthetic chelating agent that binds stray metal ions, helping products stay clear, stable and effective throughout their shelf life. By sequestering metals it keeps preservatives potent and protects sensitive actives like vitamins.

While invaluable behind the scenes it remains a niche additive rather than a headline ingredient so most shoppers never notice it on the label, yet formulators rely on its performance to keep many creams and serums from going bad.

Current data shows it is low risk for all skin types including sensitive skin, vegans and those who are pregnant or breastfeeding. As with any new cosmetic it is wise to perform a small patch test when first trying a product that contains this ingredient to confirm personal compatibility.

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