What Is Disodium Sebacoyl Bis-Lauramidolysine?
Disodium Sebacoyl Bis-Lauramidolysine is a lab crafted ingredient that joins parts of natural building blocks found in our bodies and in plants. Chemists start with lysine, an amino acid that gives proteins their strength, and couple it with sebacic acid, a plant based compound often sourced from castor oil. They then attach lauric acid chains, neutralize the mix with a pinch of sodium and end up with a water friendly powder that blends smoothly into creams and liquids.
This amino acid-based conditioner showed up in cosmetic labs in the early 2000s when formulators were hunting for gentle substitutes for silicone and animal derived proteins. Because the molecule is built to mimic the way natural proteins hug hair and skin, it quickly earned a spot in premium personal care lines.
You will spot Disodium Sebacoyl Bis-Lauramidolysine in rinse off and leave in hair conditioners, shampoos, treatment masks, styling creams, facial moisturizers, anti-aging serums and soothing body lotions. Its touch of protein like care makes it welcome in products that promise softness and a healthy glow.
Disodium Sebacoyl Bis-Lauramidolysine’s Cosmetic Benefits/Uses
This ingredient steps in as a multitasker that smooths, softens and supports the skin’s barrier while leaving hair sleek and easy to manage.
- Hair conditioning: Forms a light film that helps seal the cuticle, reduces frizz and adds slip for easier detangling. Because it is water dispersible it rinses clean without heavy buildup, leaving hair soft and bouncy.
- Skin conditioning: Binds to the skin’s surface to boost moisture retention, gives a silky after-feel and can improve the look of rough or dry patches. Its protein like structure may also support a smoother texture over time.
Who Can Use Disodium Sebacoyl Bis-Lauramidolysine
This conditioning agent is generally well tolerated by all skin and hair types, including dry, normal, combination and oily. Because the molecule is lightweight and water friendly it does not clog pores, so even those prone to breakouts can usually enjoy it without worry. Sensitive skin users also tend to do well since the ingredient is considered low irritant, though anyone with a known allergy to amino acid derivatives should remain cautious.
Disodium Sebacoyl Bis-Lauramidolysine is synthesized entirely from plant sourced or mineral components and contains no animal by-products, making it suitable for both vegans and vegetarians.
No data suggest problems for women who are pregnant or breastfeeding when the ingredient is used topically at cosmetic levels. Still, this is not medical advice and expecting or nursing mothers should run any skincare or haircare product past a qualified health professional to be on the safe side.
The ingredient does not absorb UV light and is not known to increase photosensitivity. It also plays well with common actives such as vitamin C, niacinamide and mild exfoliating acids, so you can layer it without special precautions.
Potential Side Effects/Adverse Reactions
Side effects and reactions to the topical application of Disodium Sebacoyl Bis-Lauramidolysine can vary from person to person. The points below list potential issues and are unlikely to be the typical user experience. When the ingredient has been formulated correctly most people will not notice any negative effects.
- Mild skin irritation – rare tingling or redness in very sensitive individuals
- Contact dermatitis – isolated reports of localized rash in users with preexisting allergies to amino acid derivatives
- Eye stinging – temporary discomfort if a high concentration rinse off product accidentally gets into the eyes
If any of these reactions occur discontinue use and consult a healthcare professional or dermatologist for guidance.
Comedogenic Rating
Rating: 0–1 (very low)
Disodium Sebacoyl Bis-Lauramidolysine is water dispersible, lightweight and forms a breathable micro film rather than an oily coat, so it is unlikely to block pores. Its amino acid based backbone helps it rinse clean without residue which keeps the chance of congestion low.
Because of this low rating it is generally suitable for people who are prone to acne or frequent breakouts.
As with any conditioning agent, a formula packed with heavy butters or waxes could still trigger blemishes so the overall product matters as much as the single ingredient.
Summary
Disodium Sebacoyl Bis-Lauramidolysine is a plant derived amino acid conditioner that smooths hair, boosts skin hydration and supports a softer barrier by laying down a thin protein like veil that holds moisture while rinsing away clean. Its ability to mimic natural keratin makes it a handy silicone alternative in premium shampoos, masks, serums and lotions.
Though not as famous as big name humectants or silicones, brands that lean into gentle science backed ingredients have been adopting it more often, especially in products that promise a lightweight feather feel.
Current data show it is safe for topical use with a very low irritation and comedogenic profile. Still, skin can be unpredictable so it is wise to patch test any new product that contains this ingredient before making it a daily staple.