Dodecylhexadecanol: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Dodecylhexadecanol?

Dodecylhexadecanol, also known as 2-dodecylhexadecanol, is a long-chain fatty alcohol made of 28 carbon atoms. It is often sourced from plant oils that are rich in fatty acids such as coconut or palm. Chemists reduce these natural oils in a process called hydrogenation, which turns the fatty acids into stable, waxy alcohols. This gives the ingredient its smooth texture and keeps it solid at room temperature.

The use of fatty alcohols in beauty products dates back to the mid-1900s when formulators were looking for natural options to soften creams and keep oil and water mixed. Dodecylhexadecanol gained attention for its balance of richness and spreadability, making it easier to apply than thicker waxes yet more nourishing than lighter alcohols.

Today it appears in a wide range of products: moisturizers that aim to lock in hydration, night creams and anti-aging formulas that need a plush finish, face masks that rely on a stable emulsion, and body lotions meant for very dry skin. It can also pop up in hair conditioners where extra slip and softness are desired.

Dodecylhexadecanol’s Cosmetic Benefits/Uses

This multitasking ingredient adds performance and a pleasant feel to many personal care products.

  • Emulsion stabilising: Helps keep oil and water phases from separating so creams stay smooth from the first use to the last
  • Skin conditioning: Leaves a soft supple feel on the skin surface and can reduce roughness over time
  • Emollient: Forms a light protective layer that slows moisture loss making skin feel hydrated and comfortable

Who Can Use Dodecylhexadecanol

Dodecylhexadecanol suits most skin types, especially normal to very dry or mature skin that enjoys a richer feel. People with extremely oily or blemish-prone skin might find it a bit heavy if used in high amounts, so lighter formulas are a better pick for them.

The ingredient is usually sourced from coconut or palm oil which makes it suitable for vegans and vegetarians. If the product also carries a certified vegan logo you can be confident no animal-derived additives were used.

Current safety data shows no known risks for women who are pregnant or breastfeeding when the ingredient is applied to skin. That said this is not medical advice and anyone expecting or nursing should run any skincare product past a qualified doctor to be on the safe side.

Dodecylhexadecanol does not cause photosensitivity so it will not make skin more likely to burn in the sun. It also plays well with most other cosmetic ingredients so compatibility issues are rare.

Potential Side Effects/Adverse Reactions

Side effects and reactions to topical Dodecylhexadecanol can vary from person to person. The points below list potential issues only and most users will not experience them when the ingredient is used in a properly formulated product.

  • Mild skin irritation: A small number of people may notice temporary redness stinging or itching
  • Allergic contact dermatitis: Very rare but possible if someone is sensitive to fatty alcohols
  • Clogged pores: Heavy leave-on products with high levels of the ingredient may contribute to breakouts in acne-prone skin
  • Build-up on hair: In conditioners overuse can leave strands feeling heavy or greasy

If any unwanted reaction occurs stop using the product and consult a healthcare professional for advice.

Comedogenic Rating

Rating: 2 out of 5

Dodecylhexadecanol is a long chain fatty alcohol that stays mostly on the skin surface rather than sinking deeply into pores. Its waxy nature gives it mild occlusive properties that can trap some sebum if used at high levels, yet the molecule is too bulky to penetrate easily which keeps the clogging risk on the lower side. Because of this balance formulators generally consider it mildly comedogenic but not a top offender.

People who are prone to acne can usually tolerate it in lightweight or rinse off products, though very rich leave on formulas may still feel heavy for oily skin.

Worth noting: the final comedogenic impact depends heavily on the entire formula, application amount, and how often you layer other occlusive products on top.

Summary

Dodecylhexadecanol works as an emollient, skin conditioner and emulsion stabiliser. Its long carbon chain melts into a soft film that locks in moisture while giving creams a smooth glide. At the same time the waxy structure helps keep oil and water mixed so the product stays uniform during storage and use.

The ingredient is popular in richer moisturisers and overnight masks though it remains less talked about than heavyweight staples like shea butter or jojoba oil.

Current safety data shows it is well tolerated with a low rate of irritation or allergy. As with any new skincare ingredient it is wise to patch test a small area first to make sure your skin agrees with it before applying liberally.

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