Endomyces/Sodium Hyaluronate Ferment Filtrate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Endomyces/Sodium Hyaluronate Ferment Filtrate?

Endomyces/Sodium Hyaluronate Ferment Filtrate is a skin care ingredient created when the yeast Endomyces ferments sodium hyaluronate, the salt form of hyaluronic acid. During fermentation the yeast breaks the large hyaluronic acid molecules into smaller pieces and releases amino acids, peptides and sugars that stay in the liquid. The finished filtrate is a clear lightweight fluid rich in low-molecular-weight hyaluronic fragments that are easier for skin to absorb.

Fermentation technology gained popularity in Japan and Korea in the 1990s for its ability to produce gentler, more bio-available actives. As brands searched for new ways to boost hydration without heavy oils, chemists turned to fermenting sodium hyaluronate with friendly yeasts like Endomyces. The process is straightforward: dissolve pharmaceutical-grade sodium hyaluronate in water, add a starter culture of Endomyces, let it ferment in a temperature-controlled tank for several days, then filter out the yeast cells and sterilize the liquid.

Because the filtrate delivers light yet lasting moisture it shows up in water-based products such as serums, essences, sheet masks, gel moisturizers, eye creams, anti-aging ampoules and after-sun treatments. Brands often spotlight it in formulations marketed for dull, dehydrated or mature skin.

Endomyces/Sodium Hyaluronate Ferment Filtrate’s Cosmetic Benefits/Uses

This fermented hydrator offers two main functions in topical products:

  • Humectant – attracts water from the environment and draws it into the upper layers of skin which helps plump fine lines and smooth rough texture
  • Skin conditioning – supports a soft, supple feel by reinforcing the moisture barrier and improving overall skin comfort without adding greasiness

Who Can Use Endomyces/Sodium Hyaluronate Ferment Filtrate

This lightweight ferment is generally well tolerated across all skin types. Oily or acne-prone skin benefits from its water based texture that hydrates without adding oil while dry or mature skin appreciates its ability to pull moisture into the surface layers. Sensitive skin usually handles the ingredient well because it is low in fragrance and alcohol, though anyone with a known yeast allergy should proceed carefully.

The raw materials come from plant sourced glucose and pharmaceutical grade yeast so the final filtrate is considered suitable for both vegans and vegetarians. No animal derived substances are involved at any stage of production.

Current safety data shows no issues for topical use during pregnancy or breastfeeding. That said this information is not medical advice and anyone expecting or nursing should run new products by a qualified physician to be safe.

The filtrate does not increase photosensitivity so it will not make skin more prone to sunburn. Normal daily sun protection is still recommended for overall skin health.

Potential Side Effects/Adverse Reactions

Responses to any cosmetic ingredient differ from person to person. The points below list potential side effects of Endomyces/Sodium Hyaluronate Ferment Filtrate when applied to skin. These outcomes are uncommon and most users will not notice problems if the formula has been made correctly.

  • Redness or mild irritation in extremely reactive skin
  • Itching or stinging when applied to broken or compromised skin
  • Allergic contact dermatitis in individuals sensitive to yeast derivatives
  • Malassezia folliculitis style breakouts (fungal acne) in people highly prone to this condition
  • Increased absorption of other actives in the same product which may amplify their own irritation potential

If any unwanted reaction occurs stop using the product immediately and seek advice from a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 0 / 5

Endomyces/Sodium Hyaluronate Ferment Filtrate is a water-based, oil-free ingredient that does not leave residues capable of clogging pores. Its molecules are hydrophilic, meaning they bind to water rather than sebum, so they rinse away cleanly and do not block follicular openings. For these reasons it is considered non-comedogenic.

Suitable for acne-prone or breakout-prone skin.

As always, the finished product’s overall formula can affect pore-clogging potential, so check the full ingredient list if congestion is a concern.

Summary

Endomyces/Sodium Hyaluronate Ferment Filtrate acts mainly as a humectant and skin-conditioning agent. The fermentation process chops standard sodium hyaluronate into smaller fragments and surrounds them with amino acids, peptides and sugars that boost water binding. Once applied these tiny molecules pull moisture into the upper skin layers, plump fine lines and leave the surface soft and comfortable without heaviness.

The ingredient is growing in popularity thanks to the K-beauty wave but it is still less common than classic hyaluronic acid. Brands that focus on lightweight hydration, microbiome care or fermented actives tend to showcase it in serums, essences and gel moisturizers.

Safety data shows a low risk of irritation or allergy except in people sensitive to yeast derivatives. Overall it is considered safe for regular use by most skin types. As with any new cosmetic it is wise to perform a quick patch test first to rule out individual sensitivity.

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