Enterococcus Faecalis/Amylase/Glucose/Papaya Fruit/Protease Ferment Filtrate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Enterococcus Faecalis/Amylase/Glucose/Papaya Fruit/Protease Ferment Filtrate?

Enterococcus Faecalis/Amylase/Glucose/Papaya Fruit/Protease Ferment Filtrate is a skin care ingredient obtained by fermenting a mix of papaya fruit, the enzymes amylase and protease and simple glucose sugar with the probiotic bacterium Enterococcus faecalis. During fermentation the microorganism breaks down the fruit sugars and enzyme proteins into smaller compounds, releasing beneficial peptides, amino acids and antioxidant molecules. The liquid that results is then filtered to remove any solid residue, leaving a clear watery filtrate ready for cosmetic use.

Fermented plant extracts have been part of traditional beauty rituals in many cultures, and the South Korean skin care boom helped bring modern biotech fermentation into mainstream cosmetics. Brands began pairing fruit enzymes with probiotics to create gentle actives that support skin health. This particular filtrate delivers the well known exfoliating and nourishing potential of papaya enzymes in a milder, more stable form while adding antioxidant benefits.

Production starts with ripe papaya pulp blended with food grade glucose and the naturally occurring enzymes amylase and protease. The blend is inoculated with a lab-cultured strain of Enterococcus faecalis and kept under controlled temperature and pH so the bacteria can ferment the mixture over several days. Afterward the batch is micro-filtered and sterilized to ensure safety and shelf stability before being shipped to cosmetic manufacturers.

You will most often find this ingredient in lightweight serums, essences, sheet masks, brightening lotions, anti-aging creams and rinse-off masks aimed at dull or stressed skin that needs extra radiance.

Enterococcus Faecalis/Amylase/Glucose/Papaya Fruit/Protease Ferment Filtrate’s Cosmetic Benefits/Uses

The filtrate is included in formulas mainly for its antioxidant ability, which helps neutralize free radicals generated by UV exposure and pollution. By limiting oxidative stress it supports a more even tone, keeps the skin’s surface looking fresh and works in synergy with other actives such as vitamins C and E to boost their stability and overall effectiveness.

Who Can Use Enterococcus Faecalis/Amylase/Glucose/Papaya Fruit/Protease Ferment Filtrate

This filtrate suits most skin types, including oily, combination, normal and mildly dry skin because its watery texture absorbs quickly without leaving residue while its antioxidant compounds are gentle and non-sensitising. People with very dry, eczema-prone or highly reactive skin can usually still tolerate it thanks to its low acidity, but they may prefer formulas that pair the filtrate with richer emollients to avoid tightness.

The ingredient is derived from plant matter, enzymes and a probiotic culture with no animal by-products, so it fits vegan and vegetarian lifestyles.

No data link the ferment to hormonal disruption, so it is generally considered safe for pregnant or breastfeeding women when used topically. This is not medical advice and anyone who is pregnant or nursing should show the full ingredient list of any product to a healthcare professional before using it.

The filtrate does not make skin more sensitive to sunlight, so it is not classified as photosensitising. Daily sunscreen is still recommended as part of any routine focused on antioxidant protection.

Potential Side Effects/Adverse Reactions

Side effects from topical use of Enterococcus Faecalis/Amylase/Glucose/Papaya Fruit/Protease Ferment Filtrate vary from person to person. The issues listed below are only potential outcomes and are unlikely for most users when the ingredient is formulated and applied correctly.

  • Mild stinging or tingling on very sensitive skin
  • Temporary redness or flushing, especially if layered with other exfoliating acids or retinoids
  • Allergic reaction such as itching or small hives in individuals sensitive to papaya or enzyme residues
  • Contact dermatitis triggered by other formula components rather than the ferment itself
  • Rare imbalance of the skin microbiome leading to increased breakouts if overused in high concentrations

If any persistent irritation or unexpected reaction occurs discontinue use and seek advice from a qualified healthcare provider.

Comedogenic Rating

Rating: 0 / 5. The filtrate is a thin water-like liquid with no oils, waxes or fatty alcohols that could block pores. Its active compounds are mainly soluble peptides and antioxidants that rinse or absorb away without leaving residue, so it poses virtually no risk of clogging. This makes the ingredient well suited to skin that is prone to acne or breakouts. Only the finished product’s overall formula could alter pore-clogging potential, for example if the brand combines the ferment with richer emollients.

Summary

Enterococcus Faecalis/Amylase/Glucose/Papaya Fruit/Protease Ferment Filtrate serves chiefly as an antioxidant shield. The probiotic fermentation process breaks down papaya enzymes and sugars into small bioactive molecules that scavenge free radicals, supporting brighter, healthier looking skin while helping other antioxidants stay stable. Although not as famous as vitamin C or niacinamide, the ferment has gained quiet popularity in K-beauty inspired serums and masks for its gentle nature and light feel.

Current data show it to be very safe for topical use with a low risk of irritation or pore blockage. As with any new skincare ingredient a quick patch test is wise before applying a full-face layer, just to see how your own skin responds.

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