What Is Ethyl Carbazido Hyaluronate Rh-Polypeptide-7?
Ethyl Carbazido Hyaluronate Rh-Polypeptide-7 is a hybrid molecule created by linking ethyl carbazido hyaluronate, a modified form of the moisture binding favorite hyaluronic acid, to rh-Polypeptide-7, a lab produced chain of seven amino acids modeled after naturally occurring skin peptides. The pairing unites the deep hydration talent of hyaluronic acid with the skin nurturing signals of a peptide, giving formulators a two-in-one active.
Hyaluronic acid itself was first purified from rooster comb in the 1930s but is now most often made through plant based fermentation. Scientists later discovered that attaching small chemical groups like an ethyl carbazido arm can help the molecule bind to other actives. Recombinant peptide technology arrived in skin care in the early 2000s, offering precise chains that speak the skin’s language without animal sourcing. By coupling the two, researchers created an ingredient that offers longer surface stay time and targeted activity compared with either part on its own.
Manufacturing starts with fermenting non-GMO bacteria to produce pharmaceutical-grade hyaluronic acid. This acid is reacted with ethyl carbazide to add the ethyl carbazido group. Separately, rh-Polypeptide-7 is generated in a controlled bioreactor, then purified. Finally, the two pieces are blended under specific pH and temperature conditions so the peptide bonds to the modified hyaluronate, forming a stable conjugate ready for cosmetic use.
You will usually spot Ethyl Carbazido Hyaluronate Rh-Polypeptide-7 in water-based serums, sheet masks, eye creams, anti aging moisturizers, hydrating primers and after-sun gels where brands want both quick plumping moisture and ongoing antioxidant support.
Ethyl Carbazido Hyaluronate Rh-Polypeptide-7’s Cosmetic Benefits/Uses
This dual-action ingredient brings more than hydration to a formula
- Antioxidant: Helps neutralize free radicals generated by UV rays and pollution which can lead to dullness and early fine lines. By lowering oxidative stress it supports a fresher, more even-toned look.
- Humectant: Attracts water from the environment and deeper skin layers then locks it at the surface, giving an instant plumping effect and smoothing the appearance of fine dehydration lines.
Who Can Use Ethyl Carbazido Hyaluronate Rh-Polypeptide-7
The moisture drawing nature of hyaluronic acid plus the gentle profile of small peptides makes this ingredient friendly for virtually all skin types including dry, normal, combination and oily. Even sensitive skin usually tolerates it because it is free of common irritants like fragrance and alcohol. Those with very reactive or barrier compromised skin should still check the full product formula for other triggers, but the active itself is regarded as low risk.
Ethyl Carbazido Hyaluronate Rh-Polypeptide-7 is produced through plant fermentation and recombinant biotechnology without animal derivatives, so it fits vegan and vegetarian lifestyles.
No data suggest that the molecule interferes with pregnancy or breastfeeding. It stays on the skin’s surface, is not known to penetrate into the bloodstream and has no documented hormonal activity. This is not medical advice and pregnant or nursing individuals should review any skincare they plan to use with their healthcare provider.
The ingredient does not increase photosensitivity and can be applied morning or night. Standard daytime sun protection is still recommended to guard against UV damage overall.
Potential Side Effects/Adverse Reactions
Responses to topical Ethyl Carbazido Hyaluronate Rh-Polypeptide-7 vary from person to person. The points below outline potential issues that could appear in rare cases. When the ingredient is properly formulated most users will not encounter these problems.
- Temporary redness or flushing
- Mild itching or tingling following application
- Contact dermatitis in individuals allergic to hyaluronate or peptide fragments
- Increased water loss if layered under very occlusive products that trap heat
If any persistent irritation or discomfort occurs discontinue use and seek guidance from a qualified healthcare professional.
Comedogenic Rating
Rating: 0 / 5
Ethyl Carbazido Hyaluronate Rh-Polypeptide-7 is water soluble, lightweight and does not form an oily film so it cannot clog pores. Both its hyaluronate and peptide parts sit on the skin surface and rinse away easily, which keeps the risk of blockage at zero.
That makes it a safe pick for acne-prone or breakout-prone skin.
Because it attracts water, pairing it with very heavy occlusive oils could in theory trap sweat and debris underneath but on its own the molecule remains fully non-comedogenic.
Summary
Ethyl Carbazido Hyaluronate Rh-Polypeptide-7 acts as a humectant by pulling moisture into the top layers of skin then holding it there for a plumper smoother look. At the same time its peptide arm offers antioxidant power that mops up free radicals before they can dull or age the complexion.
Right now the ingredient is more of an insider favorite than a household name. Its cost and high-tech production keep it in mid to premium formulas though that may change as demand grows.
Current research and consumer reports show a low risk of irritation or pore clogging. Still, every skin is unique so doing a small patch test with any new product is the easiest way to stay safe and comfortable.