What Is Galactose Dehydrogenase?
Galactose Dehydrogenase is an enzyme that helps convert the simple sugar galactose into other useful molecules. It is usually produced through a controlled fermentation process where safe strains of bacteria or yeast are encouraged to create the enzyme, which is then filtered and purified. While it was first studied in food science because of its role in sugar metabolism, cosmetic chemists noticed that the enzyme could improve how skin feels and looks. Today it is added to skin care formulas such as lightweight serums, hydrating masks, daily moisturizers and targeted anti-aging treatments.
Galactose Dehydrogenase’s Cosmetic Benefits/Uses
Galactose Dehydrogenase is valued in skin care for its skin conditioning ability, meaning it helps soften, smooth and maintain the skin’s moisture balance. When blended into a cream or serum it supports a healthier skin barrier, leaving the surface feeling supple and comfortable.
Who Can Use Galactose Dehydrogenase
Galactose Dehydrogenase is gentle enough for most skin types including dry, oily, combination and sensitive skin because it works mainly on the surface to support moisture rather than exfoliate or strip. There are no known reasons it would be unsuitable for any particular skin type, though people with a history of enzyme sensitivities should stay alert to how their skin responds.
The enzyme is typically produced by fermenting plant derived sugars with bacteria or yeast then purifying the finished material, so it is considered suitable for both vegans and vegetarians.
No specific warnings exist for pregnant or breastfeeding women when this ingredient is used topically in cosmetic amounts. That said, this is not medical advice and anyone who is pregnant or nursing should double-check any skin care product with a qualified healthcare provider before adding it to a routine.
Galactose Dehydrogenase does not make skin more reactive to sunlight and it does not interfere with common actives like retinol or vitamin C, so daytime use is fine as long as normal sun protection habits are followed.
Potential Side Effects/Adverse Reactions
Side effects and reactions to the topical use of Galactose Dehydrogenase can vary from person to person. The points below note potential issues that have been reported or are theoretically possible, though most users will not experience them when the ingredient is formulated and used correctly.
- Mild redness or warmth immediately after application
- Temporary itching or tingling in sensitive skin
- Rare allergic contact dermatitis presenting as a rash or swelling
- Eye irritation if the product accidentally gets into the eyes
If any of these side effects occur stop using the product and seek advice from a healthcare professional if symptoms persist or worsen.
Comedogenic Rating
Rating: 0 / 5 – Galactose Dehydrogenase is a water-soluble enzyme that does not leave an oily or waxy residue on the skin, so it has no tendency to block pores. This makes it a safe option for people who are prone to acne or breakouts.
Because the enzyme is usually delivered in lightweight formulations such as gels or serums, any risk of pore clogging generally comes from other ingredients in the same product rather than from Galactose Dehydrogenase itself.
Summary
Galactose Dehydrogenase is used in cosmetics for its skin conditioning ability, helping the skin surface feel softer, smoother and better hydrated by supporting the moisture barrier. It performs this role without exfoliating or stripping, making it gentle for daily use.
The ingredient is still a niche addition in skin care, found mainly in innovative serums and masks rather than mass-market products, but its mild nature and vegan-friendly sourcing are boosting its popularity.
Overall safety is high with very few reported adverse reactions, yet it is always wise to patch test any new product to make sure your skin tolerates the full formula.