Glucosyl Pentagallate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 27, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Glucosyl Pentagallate?

Glucosyl Pentagallate is a plant based compound built from glucose linked to five gallic acid groups. Gallic acid is a natural substance found in oak bark, tea leaves and some fruits, and attaching it to a sugar unit makes the whole molecule more water friendly so it can mix easily into creams and serums. The ingredient first caught the attention of cosmetic chemists in the early 2000s when researchers looked for strong yet stable antioxidants that would not turn products brown or lose power once exposed to air. Today manufacturers make Glucosyl Pentagallate by combining purified glucose with gallic acid through an enzymatic process that avoids harsh solvents and keeps the final powder food grade. Because it dissolves well and stays clear, brands add it to lightweight lotions, anti aging emulsions, soothing sheet masks, brightening essences and after sun gels where long term protection against environmental stress is desired.

Glucosyl Pentagallate’s Cosmetic Benefits/Uses

In skincare formulas Glucosyl Pentagallate works as a potent antioxidant. It helps neutralize free radicals produced by UV light, pollution and daily stress so the skin’s own proteins and lipids stay healthier for longer. This protection can translate to a more even tone, fewer fine lines and less dullness over time while also helping the product itself keep its color and scent fresh.

Who Can Use Glucosyl Pentagallate

Glucosyl Pentagallate is gentle enough for most skin types. Its water-loving nature means it sits lightly on oily skin without feeling greasy, yet it also adds an extra shield for dry or mature skin that needs help fighting daily damage. Sensitive complexions usually tolerate it well because the molecule is stable and has a low chance of causing stinging or redness. There are no known issues for darker skin tones or acne-prone skin.

The ingredient is made from plant sugar and gallic acid sourced from botanical feedstocks, with no animal-derived steps, so it meets vegan and vegetarian standards.

Current research shows no specific risks for people who are pregnant or breastfeeding. It is not absorbed deeply, does not act on hormones and is used in very low amounts. Still, this is not medical advice and anyone who is pregnant or nursing should show the full ingredient list of any product to a doctor before use, just to be safe.

Glucosyl Pentagallate does not make skin more sensitive to sunlight, so there is no added risk of sunburn beyond normal exposure. It can be paired with sunscreen and other antioxidants without trouble.

Potential Side Effects/Adverse Reactions

Reactions to topical Glucosyl Pentagallate vary from person to person. The points below list potential issues, but most users will not notice any problems when the product is made and used as intended.

  • Mild redness or warmth – rare and usually short-lived if it happens
  • Temporary itching – typically linked to very sensitive skin or broken skin barriers
  • Contact dermatitis – uncommon allergic response that may include rash or swelling
  • Eye irritation – possible if the product is accidentally rubbed into the eyes

If you experience any of these effects stop using the product and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 0 / 5

Glucosyl Pentagallate is fully water soluble and lacks heavy oils or waxes that can block pores, so it does not linger on the skin surface or mix with sebum. Lab and consumer reports show no link between this molecule and the formation of blackheads or pimples, giving it a non-comedogenic score of 0.

Because of this low score the ingredient is considered suitable for people prone to acne or breakouts.

Keep in mind that the overall pore-friendliness of a product also depends on the rest of the formula, so check the full ingredient list if congestion is a concern.

Summary

Glucosyl Pentagallate is a plant derived antioxidant that helps neutralize free radicals, shields skin proteins and lipids from daily damage, and stabilizes the color and scent of cosmetic formulas. It achieves these benefits through the five gallic acid groups attached to a glucose core, a structure that gives strong radical scavenging ability while staying water friendly and clear in solution.

Although it is not a buzzword ingredient like vitamin C or niacinamide it is quietly gaining ground in modern creams, serums and sheet masks thanks to its stability and gentle profile.

Current research and user feedback place it among the safer skincare additives, with very low rates of irritation or clogging. As with any new product though it is wise to perform a quick patch test to see how your own skin responds.

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